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  1. This is a comprehensive characteristic study of Kawasaki disease (KD) and Multi system inflammatory syndrome in children (MIS-C) in the Middle East that creates a formula to differentiate between the two.

    Authors: Lemis Yavuz, Sarmad AlHamdani, Samah Alasrawi, Deena Wafadari, Ali Al-Fraihat, Marwa A. Bebars, Jaidev Nath, Diego Arango, Marco Pallavidino, Ruchi Jain, Sinan Yavuz, Mohamed AlAwadhi, Abdulla Alkhayat, Ahmad Abou Tayoun and Walid Mohammad Abuhammour
    Citation: Pediatric Rheumatology 2023 21:64
  2. Juvenile Dermatomyositis (JDM) is a rare, chronic, and life-threatening childhood autoimmune disease. Currently, there are recommended, reliable and validated measurement tools for assessment of skin disease a...

    Authors: Alexander Gebreamlak, Katherine M. Sawicka, Rose Garrett, Y. Ingrid Goh, Kayla M. Baker and Brian M. Feldman
    Citation: Pediatric Rheumatology 2023 21:63
  3. Childhood-onset Systemic Lupus Erythematosus (cSLE) is an autoimmune disease associated with fatigue, mood symptoms, and pain. Fortunately, these symptoms are potentially modifiable with psychological interven...

    Authors: Natoshia R. Cunningham, Alaina Miller, Samantha L. Ely, Mallet R. Reid, Ashley Danguecan, Sarah I. Mossad, Luana Flores Pereira, Khalid Abulaban, Elizabeth Kessler, Natalie Rosenwasser, Kabita Nanda, Tamar Rubinstein, Mathew Reeves, Sara Ahola Kohut, Jennifer Stinson, Tala El Tal…
    Citation: Pediatric Rheumatology 2023 21:61
  4. Joint acoustic emissions from knees have been evaluated as a convenient, non-invasive digital biomarker of inflammatory knee involvement in a small cohort of children with Juvenile Idiopathic Arthritis (JIA). ...

    Authors: Quentin Goossens, Miguel Locsin, Sevda Gharehbaghi, Priya Brito, Emily Moise, Lori A Ponder, Omer T Inan and Sampath Prahalad
    Citation: Pediatric Rheumatology 2023 21:59
  5. Children with juvenile idiopathic arthritis (JIA) are at higher risk of decreased bone mineral density (BMD) compared with healthy children due to genetic, disease and medication-related causes. This study aim...

    Authors: Riham Eid, Maha Abdelsalam, Aya Ahmed Fathy, Hadil M. Abolenein, Eman Bakr Elmarghany, Aya Ahmed El-Hanafy, Nashwa Hamdy, Dina Salama Abd-Elmagid, Nermeen A. Niazy and Dina M. Abd-El Ghaffar
    Citation: Pediatric Rheumatology 2023 21:58
  6. Pain is one of the most frequently reported experiences amongst children with Juvenile Idiopathic Arthritis (JIA); however, the management of JIA pain remains challenging. As pain is a multidimensional experi...

    Authors: Yvonne N. Brandelli, Christine T. Chambers, Sean P. Mackinnon, Jennifer A. Parker, Adam M. Huber, Jennifer N. Stinson, Emily M. Wildeboer, Jennifer P. Wilson and Olivia Piccolo
    Citation: Pediatric Rheumatology 2023 21:57
  7. Pediatric uveitis is typically asymptomatic and may become chronic affecting ocular structures and vision. We evaluated visual outcomes, clinical features, medication, and uveitis activity in children with eit...

    Authors: Mira Siiskonen, Iida Hirn, Roosa Pesälä, Pasi Ohtonen and Nina Hautala
    Citation: Pediatric Rheumatology 2023 21:56
  8. Deficiency of adenosine deaminase 2 (DADA2) is an autosomal recessive autoinflammatory disease caused by mutations in the ADA2 gene. DADA2 has a broad spectrum of clinical presentations. Apart from systemic ma...

    Authors: Kosar Asna Ashari, Nahid Aslani, Nima Parvaneh, Raheleh Assari, Morteza Heidari, Mohammadreza Fathi, Fatemeh Tahghighi Sharabian, Alireza Ronagh, Mohammad Shahrooei, Alireza Moafi, Nima Rezaei and Vahid Ziaee
    Citation: Pediatric Rheumatology 2023 21:55
  9. Cogan´s syndrome is a rare, presumed autoimmune vasculitis of various vessels characterized by interstitial keratitis and vestibular impairment accompanied by sensorineural hearing loss. Due to the rarity of C...

    Authors: Kristina Rücklová, Thekla von Kalle, Assen Koitschev, Katrin Gekeler, Miriam Scheltdorf, Anita Heinkele, Friederike Blankenburg, Ina Kötter and Anton Hospach
    Citation: Pediatric Rheumatology 2023 21:54
  10. Juvenile Idiopathic Arthritis (JIA) is the most prevalent chronic pediatric rheumatic disorder. In joints of JIA patients, aggressive phenotypic changes in fibroblast-like synoviocytes (FLS) of the synovial li...

    Authors: Claire H. Bullock, Sarah M. McAlpine, Sarah E. Roberts and Beata Derfalvi
    Citation: Pediatric Rheumatology 2023 21:53
  11. To determine the influence of HLA-B27 positivity on risk of developing chronic nonbacterial osteomyelitis (CNO).

    Authors: Daire O’Leary, Dalila Ali Al Julandani, Muhammad Zia, Jens Klotsche, Kirsten Minden, Marion Roderick, Athimalaipet V. Ramanan, Orla G. Killeen and Anthony G. Wilson
    Citation: Pediatric Rheumatology 2023 21:52
  12. Given the impact of psychological factors on rheumatic disease, pediatric psychologists serve a vital role in promoting quality of life and managing common problems among youth with rheumatic disease. The aim ...

    Authors: Alana Goldstein-Leever, Christine Bearer, Vidya Sivaraman, Shoghik Akoghlanian, James Gallup and Stacy Ardoin
    Citation: Pediatric Rheumatology 2023 21:51
  13. To determine the clinical and laboratory differences between leukemic arthritis (LA) and juvenile idiopathic arthritis (JIA) at the onset of the disease.

    Authors: Alfonso Ragnar Torres Jimenez, Eunice Solis Vallejo, Adriana Ivonne Cespedes Cruz, Julia Veronica Ramirez Miramontes, Guadalupe del Consuelo Cortina Olvera, Alejandra Velazquez Cruz and Berenice Sanchez Jara
    Citation: Pediatric Rheumatology 2023 21:50
  14. Reliable biomarkers in the early stages of idiopathic arthritis (JIA) are scarce and the disease heterogeneity makes it clinically challenging to predict the risk of joint damage. Biomarkers with prognostic po...

    Authors: Per Lewander, Lina Wirestam, Charlotte Dahle, Jonas Wetterö and Christopher Sjöwall
    Citation: Pediatric Rheumatology 2023 21:49
  15. Primary Hypertrophic Osteoarthropathy (PHO), also known as Touraine-Solente-Gole Syndrome, is a rare, multisystemic autosomal recessive disorder caused by pathogenic variants in the 15-hydroxyprostaglandin deh...

    Authors: Rafaela Nicolau, Tiago Beirão, Francisca Guimarães, Francisca Aguiar, Sara Ganhão, Mariana Rodrigues, Ana Grangeia and Iva Brito
    Citation: Pediatric Rheumatology 2023 21:48

    The Correction to this article has been published in Pediatric Rheumatology 2023 21:62

  16. This study aimed to describe the prevalence of the various clinical features and severity of juvenile systemic lupus erythematosus (jSLE) and to assess predictors of AQP4-Ab positivity in jSLE. In addition, we...

    Authors: Yasmeen Shaaban, Hala EL-Marsafawy, Reham M El-Farahaty, Sherine El-Ziny and Ahmed M EL-Refaey
    Citation: Pediatric Rheumatology 2023 21:47
  17. Paediatric patients with autoimmune rheumatic diseases (pARD) are often immunocompromised because of the disease and/or the therapy they receive. At the beginning of COVID-19 pandemic there was a great concern...

    Authors: Tjaša Šinkovec Savšek, Mojca Zajc Avramovič, Tadej Avčin, Miša Korva, Tatjana Avšič Županc and Nataša Toplak
    Citation: Pediatric Rheumatology 2023 21:46
  18. Epidemiological studies have demonstrated a wide, unexplained disparity in the prevalence of juvenile idiopathic arthritis (JIA) subtypes depending on geographical location, ethnicity and other factors. Enthes...

    Authors: Oi Man Chan, Billy Ming-Hei Lai, Agnes Sze-Yin Leung, Ting Fan Leung and Assunta Chi-Hang Ho
    Citation: Pediatric Rheumatology 2023 21:45
  19. Oligoarticular juvenile idiopathic arthritis (oligo-JIA) is considered as an antigen-driven lymphocyte-mediated autoimmune disease. Natural antibodies (NAbs) are pre-immune antibodies produced in the absence o...

    Authors: Elena Tsitsami, Ioannis Sarrigeorgiou, Maria Tsinti, Erasmia C. Rouka, Sotirios G. Zarogiannis and Peggy Lymberi
    Citation: Pediatric Rheumatology 2023 21:44
  20. To summarize the clinical characteristics and identify the risk factors for pediatric Takayasu arteritis (TAK) with coronary artery lesions (CALs).

    Authors: Yingjie Xu, Lingfeng Luo, Gaixiu Su, Jia Zhu, Min Kang, Dan Zhang, Jianming Lai and Xiaohui Li
    Citation: Pediatric Rheumatology 2023 21:42
  21. Juvenile localized scleroderma (LS) and systemic sclerosis (SSc) are rare pediatric conditions often associated with severe morbidities. Delays in diagnosis are common, increasing the risk for permanent damage...

    Authors: Leigh A. Stubbs, Andrew M. Ferry, Danielle Guffey, Christina Loccke, Erin Moriarty Wade, Pamela Pour, Kaveh Ardalan, Peter Chira, Ingrid M. Ganske, Daniel Glaser, Gloria Higgins, Nadia Luca, Katharine F. Moore, Vidya Sivaraman, Katie Stewart, Natalia Vasquez-Canizares…
    Citation: Pediatric Rheumatology 2023 21:39
  22. This study evaluated the efficacy and safety of baricitinib (Janus kinase-1/2 inhibitor), in adult and pediatric Japanese patients with Nakajo-Nishimura syndrome/chronic atypical neutrophilic dermatosis with l...

    Authors: Nobuo Kanazawa, Taeko Ishii, Yasushi Takita, Atsushi Nishikawa and Ryuta Nishikomori
    Citation: Pediatric Rheumatology 2023 21:38
  23. To determine whether and how often the information to measure a set of key performance indicators (KPIs) in juvenile idiopathic arthritis (JIA) is found in data collected routinely in a Pediatric Rheumatology ...

    Authors: Sarah M. Cooper, Gillian R. Currie, Seija Kromm, Marinka Twilt and Deborah A. Marshall
    Citation: Pediatric Rheumatology 2023 21:37
  24. Sarcoidosis is characterized by non-caseating epithelioid granulomas in various tissues throughout the body, most commonly the lung. Non-caseating granulomas may be seen in skeletal muscle, though typically as...

    Authors: Meagan E. Chriswell, Robert C. Fuhlbrigge, Mark A. Lovell, Matthew Monson and Jessica L. Bloom
    Citation: Pediatric Rheumatology 2023 21:36
  25. The ten-joint juvenile arthritis disease activity score (JADAS10) is designed to measure the level of disease activity in non-systemic juvenile idiopathic arthritis by providing a single numeric score. The cli...

    Authors: M. Backström, H. Salo, J. Kärki, K. Aalto, K. Rebane, T. Levälampi, M-M. Grönlund, L. Kröger, H. Pohjankoski, M. Hietanen, K. Korkatti, L. Kuusalo, V. Rantalaiho, J. Huhtakangas, H. Relas, T. Pääkkö…
    Citation: Pediatric Rheumatology 2023 21:35
  26. Kawasaki disease (KD) is a systemic inflammatory condition primarily affecting young children. Although 90% of KD patients present with variable head and neck manifestations, especially cervical lymphadenopath...

    Authors: Rim Kasem Ali Sliman, Joris M. van Montfrans, Najwan Nassrallah and Mohamad Hamad Saied
    Citation: Pediatric Rheumatology 2023 21:34
  27. Multisystem inflammatory syndrome in children (MIS-C) is a severe disease with an unpredictable course and a substantial risk of cardiogenic shock. Our objectives were to (a) compare MIS-C phenotypes across th...

    Authors: Thomas Renson, Nils D. Forkert, Kimberly Amador, Paivi Miettunen, Simon J. Parsons, Muhammed Dhalla, Nicole A. Johnson, Nadia Luca, Heinrike Schmeling, Rebeka Stevenson, Marinka Twilt, Lorraine Hamiwka and Susanne Benseler
    Citation: Pediatric Rheumatology 2023 21:33
  28. To evaluate the impact of anti-tumor necrosis factor-alpha (TNFα: etanercept [Etanercept ®]) therapy on adrenal activity in juvenile idiopathic arthritis (JIA) .

    Authors: Yonatan Butbul Aviel, Ariel Keinan, Michaela F. Hartmann, Stefan A. Wudy and Dov Tiosano
    Citation: Pediatric Rheumatology 2023 21:32
  29. To develop and evaluate German versions of the Parent Adherence Report Questionnaire (PARQ) and Child Adherence Report Questionnaire (CARQ) and to evaluate adherence in patients with juvenile idiopathic arthri...

    Authors: Sabine Kirchner, Jens Klotsche, Ina Liedmann, Martina Niewerth, Debbie Feldman, Frank Dressler, Ivan Foeldvari, Dirk Foell, Johannes-Peter Haas, Gerd Horneff, Anton Hospach, Tilmann Kallinich, J. B. Kuemmerle-Deschner, Kirsten Moenkemoeller, Frank Weller-Heinemann, Daniel Windschall…
    Citation: Pediatric Rheumatology 2023 21:31
  30. Kawasaki Disease (KD) is the leading cause of acquired heart disease in children in developed countries with a variable incidence worldwide. Previous studies reported an unexpectedly high incidence of KD in th...

    Authors: Abdulrahman Alkanhal, Joseph Saunders, Fajer Altammar, Adam M. Huber, Andrew Lynk, Alison MacLeod, Oliva Ortiz-Alvarez, Meighan Adams, Suzanne Ramsey, Elizabeth Stringer, Andrew Warren and Bianca Lang
    Citation: Pediatric Rheumatology 2023 21:30
  31. Treatment strategies for juvenile idiopathic arthritis (JIA) have shifted significantly over the last 20 years. We examined the effect of the introduction of government-subsidised TNF inhibitor (TNFi) treatmen...

    Authors: Erin Kelty, Ebony Quintrell, David B. Preen, Prue Manners and Johannes Nossent
    Citation: Pediatric Rheumatology 2023 21:29
  32. Lupus nephritis (LN) is a crucial organ involvement in systemic lupus erythematosus (SLE). Patients with LN have higher morbidity and mortality rates than those without. Among all patients with LN, 20–40% had ...

    Authors: Tzu-Chuan Hsu, Yao-Hsu Yang, Li-Chieh Wang, Jyh-Hong Lee, Hsin-Hui Yu, Yu-Tsan Lin, Ya-Chiao Hu and Bor-Luen Chiang
    Citation: Pediatric Rheumatology 2023 21:28
  33. Etanercept (ETN) is widely used tumour necrosis factor (TNF) blocker in the treatment of juvenile idiopathic arthritis (JIA) when traditional synthetic disease modifying antirheumatic drug (sDMARD) therapy is ...

    Authors: Tiina Levälampi, Johanna Kärki, Katariina Rebane, Paula Vähäsalo, Merja Malin, Liisa Kröger, Minna-Maija Grönlund, Maria Backström, Heini Pohjankoski, Hannu Kautiainen, Sakari Jokiranta and Kristiina Aalto
    Citation: Pediatric Rheumatology 2023 21:27
  34. In recent years, biologic drug therapies have altered the course of juvenile idiopathic arthritis (JIA) possibly also improving the patients’ physical fitness. However, studies measuring both cardiorespiratory...

    Authors: Kati Räsänen, Kati Markula-Patjas, Saija Kantanen, Kalle Sipilä, Timo A. Lakka, Pekka Arikoski and Eija Piippo-Savolainen
    Citation: Pediatric Rheumatology 2023 21:26
  35. Cytomegalovirus (CMV) plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). However, it is not clear whether the anti-CMV treatment has an impact on the prognosis of SLE patients w...

    Authors: Tianyu Zhang, Zhongxun Yu, Sihao Gao, Yuelun Zhang, Changyan Wang, Shan Jian, Lin Wang, Lijuan Gou, Ji Li, Mingsheng Ma and Hongmei Song
    Citation: Pediatric Rheumatology 2023 21:25
  36. Despite guidelines, poor access to appropriate care for juvenile idiopathic arthritis (JIA) patients remains a global issue. Prompt referral to a pediatric rheumatology (PR) center and effective care is known ...

    Authors: Aurélie Chausset, Céline Lambert, Alexandre Belot, Etienne Merlin, Elvira Cannizzaro, Isabelle Kone-Paut, Claire Ballot, Valérie Devauchelle, Sylvaine Poignant, Raffaella Carlomagno, Anne Lohse, Catherine Barbier, Véronique Despert, Aurélia Carbasse, Laetitia Sparsa, Eva Adank…
    Citation: Pediatric Rheumatology 2023 21:24
  37. Blau syndrome is a rare autoinflammatory disease caused by autosomal dominant mutations in the CARD15/NOD2 gene. Vascular involvement is a rare phenotype in Blau syndrome patients. In this study, we aimed to d...

    Authors: Qiaoqian Zeng, Haimei Liu, Guomin Li, Yifan Li, Wanzhen Guan, Tao Zhang, Yinv Gong, Xiaomei Zhang, Qianying Lv, Bingbing Wu, Hong Xu and Li Sun
    Citation: Pediatric Rheumatology 2023 21:23
  38. The relationship between anti-SSA/RO antibodies and pregnancy has been reported previously, and we aim to visualize the rates of maternal and infant outcomes with anti-SSA/RO.

    Authors: Xiangrui Sheng, Xiaohui Song, Yue Xiong, Tian Ren, Xin Chang, Jian Wu, Jing Cao, Tao Cheng and Mingjun Wang
    Citation: Pediatric Rheumatology 2023 21:22
  39. Adalimumab in combination with other disease-modifying antirheumatic drugs (DMARD) such as methotrexate has a proven efficacy in the management of paediatric non-infectious uveitis. However, many children expe...

    Authors: DA Al-Julandani, NK Bagri, N Tsang, S Clarke, A Upadhyay, C Guly and AV Ramanan
    Citation: Pediatric Rheumatology 2023 21:21
  40. A systematic literature review was conducted to summarize efficacy and safety data from studies that evaluated tumor necrosis factor inhibitors in patients with juvenile idiopathic arthritis (JIA).

    Authors: Gerd Horneff, Kirsten Minden, Catherine Rolland, Ana C. Hernandez Daly, Cecilia Borlenghi and Nicolino Ruperto
    Citation: Pediatric Rheumatology 2023 21:20
  41. Little is known about the association between juvenile idiopathic arthritis (JIA) and autoimmune thyroid disease (AITD) and therefore there are no indications for AITD screening in this population, which is po...

    Authors: Joeri W. van Straalen, Laurie Baas, Gabriella Giancane, Lyudmila Grebenkina, Jurgen Brunner, Gabriel Vega-Cornejo, Vyacheslav G. Chasnyk, Liora Harel, Simone Appenzeller, Elisabeth Gervais, Sytze de Roock, Nico M. Wulffraat, Nicolino Ruperto and Joost F. Swart
    Citation: Pediatric Rheumatology 2023 21:19
  42. To evaluate the efficacy of levofolinic acid (LVF) administered 48 h before methotrexate (MTX) in reducing gastrointestinal side effects without interference with drug efficacy.

    Authors: Giorgia Martini, Alessandra Meneghel, Michele Fastiggi, Filippo Dell’Apa, Fabio Vittadello and Francesco Zulian
    Citation: Pediatric Rheumatology 2023 21:18
  43. Juvenile Idiopathic Arthritis (JIA) is an autoimmune disease with a heterogenous clinical presentation and unpredictable response to available therapies. This personalized transcriptomics study sought proof-of...

    Authors: Kathleen J. Imbach, Nicole J. Treadway, Vaishali Prahalad, Astrid Kosters, Dalia Arafat, Meixue Duan, Talia Gergely, Lori A. Ponder, Shanmuganathan Chandrakasan, Eliver E. B. Ghosn, Sampath Prahalad and Greg Gibson
    Citation: Pediatric Rheumatology 2023 21:17
  44. IgG4-related disease (IgG4-RD) is a progressive and sometimes fatal disease that rarely affects pediatric age group. It may affect the orbits, lacrimal and salivary glands, pancreas, kidneys, peritoneum and ot...

    Authors: Moustafa Ali Saad, Hamdy Ahmed, Rasmia Elgohary and Hala Ibrahem El Gendy
    Citation: Pediatric Rheumatology 2023 21:16
  45. Cryopyrin-associated periodic syndrome (CAPS), a rare genetic autoimmune disease, is composed of familial cold autoinflammatory syndrome (FCAs), Muckle-Wells syndrome (MWS), and neonatal onset multisystem infl...

    Authors: Jia Liu, Ranran Zhang, Zhi Yi, Yi Lin, Hong Chang and Qiuye Zhang
    Citation: Pediatric Rheumatology 2023 21:15

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