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  1. Content type: Research article

    Kawasaki disease (KD) is an acute febrile systemic vasculitis that affects small and medium blood vessels. Intensified treatments for the most severely affected patients have been proposed recently, and the ea...

    Authors: Dima Chbeir, Jean Gaschignard, Ronan Bonnefoy, Constance Beyler, Isabelle Melki, Albert Faye and Ulrich Meinzer

    Citation: Pediatric Rheumatology 2018 16:48

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  2. Content type: Research article

    Little is known about the chronicity of orofacial symptoms and how this influences the oral health-related quality of life in juvenile idiopathic arthritis (JIA). Therefore, our objectives were to study the lo...

    Authors: Hanna Rahimi, Marinka Twilt, Troels Herlin, Lynn Spiegel, Thomas Klit Pedersen, Annelise Küseler and Peter Stoustrup

    Citation: Pediatric Rheumatology 2018 16:47

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  3. Content type: Review

    Specialized research networks are essential to achieve drug approvals for rare pediatric diseases. Such networks help realize the potential of global legislation enacted upon the recognition that most children...

    Authors: Hermine I. Brunner, Lisa G. Rider, Daniel J. Kingsbury, Dominic Co, Rayfel Schneider, Ellen Goldmuntz, Karen B. Onel, Edward H. Giannini and Daniel J. Lovell

    Citation: Pediatric Rheumatology 2018 16:45

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  4. Content type: Review

    Conventional pharmacological therapies for the treatment of juvenile idiopathic arthritis (JIA) consist of non-biological, disease-modifying antirheumatic drugs, among which methotrexate (MTX) is the most comm...

    Authors: Giovanna Ferrara, Greta Mastrangelo, Patrizia Barone, Francesco La Torre, Silvana Martino, Giovanni Pappagallo, Angelo Ravelli, Andrea Taddio, Francesco Zulian and Rolando Cimaz

    Citation: Pediatric Rheumatology 2018 16:46

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  5. Content type: Research article

    To understand the relationship between regulatory B cells (Bregs) and juvenile idiopathic arthritis (JIA), we analyzed the percentages of Bregs and their function in peripheral blood (PB) and synovial fluid (S...

    Authors: Qianzi Zhao and Lawrence K. Jung

    Citation: Pediatric Rheumatology 2018 16:44

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  6. Content type: Research article

    Juvenile idiopathic arthritis (JIA) is an inflammatory arthritis of unknown etiology, which lasts for greater than 6 weeks with onset before 16 years of age. JIA is the most common chronic rheumatic disease in...

    Authors: Daniel J. Lovell, Jason A. Dare, Megan Francis-Sedlak, Julie Ball, Brian D. LaMoreaux, Emily Von Scheven, Adam Reinhardt, Rita Jerath, Oral Alpan, Ramesh Gupta, Donald Goldsmith, Andrew Zeft, Henry Naddaf, Beth Gottlieb, Lawrence Jung and Robert J. Holt

    Citation: Pediatric Rheumatology 2018 16:41

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  7. Content type: Research article

    Juvenile dermatomyositis (JDM) is the most common inflammatory myopathy in childhood and a major cause of morbidity among children with pediatric rheumatic diseases. The management of JDM is very heterogeneous...

    Authors: Claas H. Hinze, Prasad T. Oommen, Frank Dressler, Andreas Urban, Frank Weller-Heinemann, Fabian Speth, Elke Lainka, Jürgen Brunner, Heike Fesq, Dirk Foell, Wolfgang Müller-Felber, Ulrich Neudorf, Christoph Rietschel, Tobias Schwarz, Ulrike Schara and Johannes-Peter Haas

    Citation: Pediatric Rheumatology 2018 16:40

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  8. Content type: Research article

    Juvenile Dermatomyositis (JDM) is a rare pediatric autoimmune disease with broad variations of the individual course. Data on the optimal management are mostly lacking. Currently treatment decisions are often ...

    Authors: Claas H. Hinze, Fabian Speth, Prasad T. Oommen and Johannes-Peter Haas

    Citation: Pediatric Rheumatology 2018 16:38

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  9. Content type: Research article

    Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)...

    Authors: Kim Ohl, Helge Nickel, Halima Moncrieffe, Patricia Klemm, Anja Scheufen, Dirk Föll, Viktor Wixler, Angela Schippers, Norbert Wagner, Lucy R. Wedderburn and Klaus Tenbrock

    Citation: Pediatric Rheumatology 2018 16:39

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  10. Content type: Research article

    Bisphosphonates are recommended for use as first-line therapy for the prevention and treatment of glucocorticoid-induced osteoporosis in adults. However, the appropriate usage of bisphosphonates for the preven...

    Authors: Yuzaburo Inoue, Kanako Mitsunaga, Takeshi Yamamoto, Koki Chiba, Fumiya Yamaide, Taiji Nakano, Yoshinori Morita, Akiko Yamaide, Shuichi Suzuki, Takayasu Arima, Ken-ichi Yamaguchi, Minako Tomiita, Naoki Shimojo and Yoichi Kohno

    Citation: Pediatric Rheumatology 2018 16:36

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  11. Content type: Short Report

    To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage I...

    Authors: Anna Agazzi, Gloria Fadanelli, Fabio Vittadello, Francesco Zulian and Giorgia Martini

    Citation: Pediatric Rheumatology 2018 16:37

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  12. Content type: Research article

    Involving people of all ages in health research is now widely advocated. To date, no studies have explored whether and how young people with chronic rheumatic conditions want to be involved in influencing heal...

    Authors: Suzanne Parsons, Wendy Thomson, Katharine Cresswell, Bella Starling and Janet E. McDonagh

    Citation: Pediatric Rheumatology 2018 16:35

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  13. Content type: Review

    Vitamin D has been implicated in the pathogenesis of autoimmune diseases. While the roles of vitamin D in other autoimmune diseases have been investigated, less is known about the role of vitamin D in chronic ...

    Authors: Sarah L. Finch, Alan M. Rosenberg and Hassan Vatanparast

    Citation: Pediatric Rheumatology 2018 16:34

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  14. Content type: Research article

    The pathogenesis of Kawasaki disease are still not well understood. It was designed to investigate the relationship between adipokines including chemerin, omentin-1, adiponectin and acute Kawasaki disease.

    Authors: Xin-yan Zhang, Ting-ting Yang, Xiu-fen Hu, Yu Wen, Feng Fang and Hui-ling Lu

    Citation: Pediatric Rheumatology 2018 16:33

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  15. Content type: Research article

    To compare final height to mid-parental target height among adults with childhood-onset systemic lupus erythematosus (cSLE) versus adult-onset SLE (aSLE), and to evaluate the impact of age at SLE onset on fina...

    Authors: Merav Heshin-Bekenstein, Liat Perl, Aimee O. Hersh, Emily von Scheven, Ed Yelin, Laura Trupin, Jinoos Yazdany and Erica F. Lawson

    Citation: Pediatric Rheumatology 2018 16:30

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  16. Content type: Correction

    Following publication of the original article [1], the authors reported that the names of two institutional authors – EUROFEVER and the Paediatric Rheumatology International Trials Organisation (PRINTO) – had ...

    Authors: Romina Gallizzi, Caterina Pidone, Luca Cantarini, Martina Finetti, Marco Cattalini, Giovanni Filocamo, Antonella Insalaco, Donato Rigante, Rita Consolini, Maria Cristina Maggio, Adele Civino, Silvana Martino, Alma Nunzia Olivieri, Giovanna Fabio, Serena Pastore, Angela Mauro…

    Citation: Pediatric Rheumatology 2018 16:29

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    The original article was published in Pediatric Rheumatology 2017 15:84

  17. Content type: Research article

    A standardized set of quality measures for juvenile idiopathic inflammatory myopathies (JIIM) is not in use. Discordance has been shown between the importance ascribed to quality measures between patients and ...

    Authors: Heather O. Tory, Ruy Carrasco, Thomas Griffin, Adam M. Huber, Philip Kahn, Angela Byun Robinson, David Zurakowski and Susan Kim

    Citation: Pediatric Rheumatology 2018 16:28

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  18. Content type: Research article

    Diagnosis of Periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) is currently based on a set of criteria proposed in 1999 modified from Marshall’s criteria. Nevertheless no validated...

    Authors: Federica Vanoni, Silvia Federici, Jordi Antón, Karyl S. Barron, Paul Brogan, Fabrizio De Benedetti, Fatma Dedeoglu, Erkan Demirkaya, Veronique Hentgen, Tilmann Kallinich, Ronald Laxer, Ricardo Russo, Natasa Toplak, Yosef Uziel, Alberto Martini, Nicolino Ruperto…

    Citation: Pediatric Rheumatology 2018 16:27

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  19. Content type: Research article

    The recurrence rate of Henoch-Schönlein purpura (HSP) is 2.7%–30%, with varied average intervals between the first and second episodes. Few studies have explored the incidence and risk factors for recurrent HSP.

    Authors: Wei-Te Lei, Po-Li Tsai, Szu-Hung Chu, Yu-Hsuan Kao, Chien-Yu Lin, Li-Ching Fang, Shyh-Dar Shyur, Yu-Wen Lin and Shu-I Wu

    Citation: Pediatric Rheumatology 2018 16:25

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  20. Content type: Research article

    Pregnant women with systemic lupus erythematosus (SLE) have increased risk of adverse outcomes including disease flare, spontaneous abortion, preeclampsia/eclampsia, premature birth and maternal death. However...

    Authors: Nicole Ling, Erica Lawson and Emily von Scheven

    Citation: Pediatric Rheumatology 2018 16:26

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  21. Content type: Research article

    Rheumatic fever (RF) is the result of an autoimmune response to pharyngitis caused by infection with Streptococcus pyogenes. RF is most prevalent in Africa and the Middle East. Rheumatic heart disease (RHD) is th...

    Authors: Maher Hassan Gomaa, Shawkey Sadik Ali, Aya Mohamed Fattouh, Hala Salah Hamza and Mohamed Mohamed Badr

    Citation: Pediatric Rheumatology 2018 16:24

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