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  1. Childhood leukemia with musculoskeletal (MSK) involvement mimics various conditions, which consequently leads to diagnostic delays. The clinical implication of MSK involvement in this disease on survival outco...

    Authors: Sirinthip Kittivisuit, Pornpun Sripornsawan, Natsaruth Songthawee, Shevachut Chavananon, Edward B. McNeil and Thirachit Chotsampancharoen
    Citation: Pediatric Rheumatology 2022 20:34
  2. This retrospective, cross-sectional study aimed to assess the pharyngeal airway dimensions of patients with juvenile idiopathic arthritis (JIA) and moderate/severe JIA-related dentofacial deformity (mandibular...

    Authors: Xiaowen Niu, Julianne Moland, Thomas Klit Pedersen, Anders Ellern Bilgrau, Paolo M. Cattaneo, Mia Glerup and Peter Stoustrup
    Citation: Pediatric Rheumatology 2022 20:32
  3. A higher prevalence of celiac disease (CD) has been reported in patients with juvenile idiopathic arthritis (JIA) compared to the general population. Factors related to the increased risk of co-occurrence and ...

    Authors: Roberta Naddei, Simona Di Gennaro, Alfredo Guarino, Riccardo Troncone, Maria Alessio and Valentina Discepolo
    Citation: Pediatric Rheumatology 2022 20:31
  4. Environmental exposures have been associated with the juvenile idiopathic inflammatory myopathies (JIIM). We undertook a questionnaire-based study to evaluate patient-reported exposures as possible risk factor...

    Authors: Jonathan C. Scalabrini, Adam I. Schiffenbauer, Payam Noroozi Farhadi, Rita Volochayev, Nastaran Bayat, Anna Jansen, Ira N. Targoff, Frederick W. Miller and Lisa G. Rider
    Citation: Pediatric Rheumatology 2022 20:28
  5. In Oman, the ““transition” of health care of adolescents to adult care occurs at a young age, like many other GCC countries for cultural reasons. In order to address this concern, this study was conducted to d...

    Authors: Reem Abdwani, Rumaitha Al Sabri, Zawan Al Hasni, Seyad Rizvi, Humaid Al Wahshi, Batool Al Lawati, Safiya Al Abrawi, Yassir Wali and Mona Al Sadoon
    Citation: Pediatric Rheumatology 2022 20:27
  6. The plasticity of T helper-17 (Th17) and regulatory T (Treg) cells may be a clue to pathogenesis of Juvenile Idiopathic Arthritis (JIA). It is still unclear, whether targeted suppression of Interleukin (IL)-17...

    Authors: Marie-Therese Holzer, Giovanni Almanzar, Robert Woidich, Boris Hügle, Johannes-Peter Haas and Martina Prelog
    Citation: Pediatric Rheumatology 2022 20:26
  7. Pharmacological treatment is a cornerstone of care for children with juvenile idiopathic arthritis (JIA). The objective of this study is to evaluate prescription patterns of conventional and biologic disease m...

    Authors: Luiza R. Grazziotin, Gillian Currie, Marinka Twilt, Maarten J. Ijzerman, Michelle M. A. Kip, Hendrik Koffijberg, Susanne M. Benseler, Joost F. Swart, Sebastiaan J. Vastert, Nico M. Wulffraat, Rae S. M. Yeung and Deborah A. Marshall
    Citation: Pediatric Rheumatology 2022 20:25
  8. Singleton-Merten syndrome 1 (SGMRT1) is a rare type I interferonopathy caused by heterozygous mutations in the IFIH1 gene. IFIH1 encodes the pattern recognition receptor MDA5 which senses viral dsRNA and activate...

    Authors: Philip Broser, Ursula von Mengershausen, Katrin Heldt, Deborah Bartholdi, Dominique Braun, Christine Wolf and Min Ae Lee-Kirsch
    Citation: Pediatric Rheumatology 2022 20:24
  9. Core sets, while widely adopted for clinical assessment in juvenile dermatomyositis (JDM), have some drawbacks – they are time consuming, were developed primarily for research, and require an experienced multi...

    Authors: Saunya Dover, Samantha Stephens, Hayyah Clairman, Andrew Abesamis, Omidali Aghababaei Jazi, Stephanie Babij, Jo-Anne Marcuz, Natasha Naraidoo, Jing Pan, Eleanor Pullenayegum, Dax Rumsey, Kristi Whitney and Brian M. Feldman
    Citation: Pediatric Rheumatology 2022 20:21
  10. Our aims were to clinically and epidemiologically characterize rheumatic fever (RF) in the current era in Israel. Although there has been a steady decline in the incidence of RF in the western world, evidence ...

    Authors: Rotem Tal, Mohamad Hamad Saied, Razi Zidani, Yoel Levinsky, Rachel Straussberg, Jacob Amir, Gil Amarilyo and Liora Harel
    Citation: Pediatric Rheumatology 2022 20:20
  11. Social determinants of health (SDH) greatly influence outcomes during the first year of treatment in rheumatoid arthritis, a disease similar to polyarticular juvenile idiopathic arthritis (pJIA). We investigat...

    Authors: William Daniel Soulsby, Nayimisha Balmuri, Victoria Cooley, Linda M. Gerber, Erica Lawson, Susan Goodman, Karen Onel and Bella Mehta
    Citation: Pediatric Rheumatology 2022 20:18
  12. Pediatric antiphospholipid syndrome (APS) is a thromboinflammatory disease characterized by the presence of circulating antiphospholipid antibodies and either thrombotic events or pregnancy morbidity. The obje...

    Authors: Jacqueline A. Madison, Kelsey Gockman, Claire Hoy, Ajay Tambralli, Yu Zuo and Jason S. Knight
    Citation: Pediatric Rheumatology 2022 20:17
  13. Macrophage activation syndrome (MAS) is a severe and under-recognized complication of rheumatologic diseases. We describe a patient who presented with rapidly progressive, refractory MAS found to have anti-MD...

    Authors: J. Alex Stewart, Theresa Price, Sam Moser, Dolores Mullikin and Angela Bryan
    Citation: Pediatric Rheumatology 2022 20:16
  14. Patients with juvenile chronic inflammatory systemic diseases (jCID) are vulnerable to many circumstances when transitioning to adult-centered healthcare; this increases the burden of disease and worsen their ...

    Authors: Fernando García-Rodríguez, Karina Raygoza-Cortez, Lesli Moreno-Hernandez, Rodrigo García-Pérez, Leticia Elizabeth Garza Lopez, Ana Cecilia Arana-Guajardo, Joel Omar Jáquez-Quintana, Ana Victoria Villarreal-Treviño, Manuel Enrique de la O-Cavazos and Nadina Rubio-Pérez
    Citation: Pediatric Rheumatology 2022 20:15
  15. While the general relationship between ACEs and the development of chronic pain has become increasingly clear, how ACEs may shape a child’s clinical presentation with regards to chronic pain has yet to be full...

    Authors: Maitry Sonagra, Jeremy Jones, Mackenzie McGill and Sabrina Gmuca
    Citation: Pediatric Rheumatology 2022 20:14
  16. Describe the frequency of thrombotic and non-thrombotic clinical manifestations, laboratory, treatment and prognosis in patients with pediatric primary antiphospholipid syndrome.

    Authors: Alfonso-Ragnar Torres-Jimenez, Virginia Ramirez-Nova, Adriana Ivonne Cespedes-Cruz, Berenice Sanchez-Jara, Alejandra Velazquez-Cruz, Vilma Carolina Bekker-Méndez and Francisco Xavier Guerra-Castillo
    Citation: Pediatric Rheumatology 2022 20:13
  17. In comparison with the general population, adolescents with juvenile idiopathic arthritis (JIA) are at higher risk for morbidity and mortality. However, limited evidence is available about this condition’s und...

    Authors: Kimberly A. Lewis, Nico Osier, Ruy Carrasco, Jennifer Chiou, Patricia Carter, Alexandra Garcia, Elena Flowers, Efstathios D. Gennatas, Christina Nguyen, Ambreen Rana, Sharon A. Brown and Stefano Tiziani
    Citation: Pediatric Rheumatology 2022 20:12
  18. Nailfold capillary microscopy (NCM) is a cornerstone in the diagnosis of Systemic Sclerosis (SSc) in adulthood. Although Raynaud’s phenomenon (RP) is very common in childhood, studies on diagnostic methods to ...

    Authors: Claudette A. Farenhorst, Anniek M. Roon, Anne I. Gessel, Alja J. Stel, Hendrika Bootsma, Wineke Armbrust and Douwe J. Mulder
    Citation: Pediatric Rheumatology 2022 20:11
  19. The translation of research findings into clinical practice is challenging, especially fields like in pediatric rheumatology, where the evidence base is limited, there are few clinical trials, and the conditio...

    Authors: Cagri Yildirim-Toruner, Rajdeep Pooni, Y. Ingrid Goh, Emily Becker-Haimes, James W. Dearing, Maria E. Fernandez, Esi M. Morgan, Gareth Parry, Jon M. Burnham, Stacy P. Ardoin, Fatima Barbar-Smiley, Joyce C. Chang, Peter Chiraseveenuprapund, Vincent Del Gaizo, Guy Eakin, Lisa C. Johnson…
    Citation: Pediatric Rheumatology 2022 20:10
  20. An association of different autoimmune diseases is suspected. In juvenile idiopathic arthritis (JIA), only few and partially conflicting data on the co-existence of other autoimmune disorders are available. Th...

    Authors: Caroline Schulz, Sabrina Fuehner, Bernhard Schlüter, Manfred Fobker, Claudia Sengler, Jens Klotsche, Martina Niewerth, Kirsten Minden and Dirk Foell
    Citation: Pediatric Rheumatology 2022 20:8
  21. In women with autoimmune rheumatic disorders (ARD), pregnancy complications or postpartum events are more frequent compared to the general population. Transplacental autoantibodies or cytokines influence vario...

    Authors: Soo Yeun Sim, Hye Yeon Choi, Min Ho Jung, Soo Young Lee, Jung Woo Rhim, Hyun Mi Kang and Dae Chul Jeong
    Citation: Pediatric Rheumatology 2022 20:7
  22. Few published data describe how joint involvement, the most prevalent extraintestinal manifestation, affects quality of life (QoL) of children with Crohn’s disease (CD). Arthritis and arthralgia rates in pedia...

    Authors: Beata Derfalvi, Kriszta Katinka Boros, Doloresz Szabo, Gabor Bozsaki, Aron Cseh, Gabor Rudas, Katalin Eszter Muller and Gabor Veres
    Citation: Pediatric Rheumatology 2022 20:6
  23. Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease. Intra-articular corticosteroids joint injection (IAJI), with triamcinolone hexacetonide (TH) or triamcinolone acetonide (TA),...

    Authors: Shiri Rubin, Orly Ohana, Ori Goldberg, Orit Peled, Yulia Gendler, Zohar Habot-Wilner, Yoel Levinsky, Rotem Tal, Liora Harel and Gil Amarilyo
    Citation: Pediatric Rheumatology 2022 20:5
  24. Growth impairment is the most common complication in patients with childhood-onset systemic lupus erythematosus (cSLE). There are limited data on risk factors affecting growth development in Asian patients wit...

    Authors: Lalita Ponin, Preamrudee Poomthavorn, Kwanchai Pirojsakul, Butsabong Lerkvaleekul, Sirisucha Soponkanaporn, Niyata Chitrapazt and Soamarat Vilaiyuk
    Citation: Pediatric Rheumatology 2022 20:4
  25. Juvenile idiopathic arthritis (JIA) is a cluster of autoimmune rheumatic diseases occurring in children 16 years of age or less. While it is well-known that pain may be experienced during inflammatory and non-...

    Authors: Hanne Van Der Heijden, Benoit Fatou, Diana Sibai, Kacie Hoyt, Maria Taylor, Kin Cheung, Jordan Lemme, Mariesa Cay, Benjamin Goodlett, Jeffery Lo, Melissa M. Hazen, Olha Halyabar, Esra Meidan, Rudy Schreiber, Camilo Jaimes, Kirsten Ecklund…
    Citation: Pediatric Rheumatology 2022 20:3
  26. The aim of this study was to evaluate demographic, clinical, laboratory, imaging, histopathology characteristics, and treatment responses of children with Chronic nonbacterial osteomyelitis (CNO).

    Authors: Le Ma, Haimei Liu, Hanyun Tang, Zhiyong Zhang, Lixia Zou, Haiguo Yu, Li Sun, Xiaozhong Li, Xuemei Tang and Meiping Lu
    Citation: Pediatric Rheumatology 2022 20:1
  27. This study aimed to perform an immunoprofiling of systemic juvenile idiopathic arthritis (sJIA) in order to define biomarkers of clinical use as well as reveal new immune mechanisms.

    Authors: Heshuang Qu, Erik Sundberg, Cecilia Aulin, Manoj Neog, Karin Palmblad, Anna Carin Horne, Fredrik Granath, Alexandra Ek, Erik Melén, Mia Olsson and Helena Erlandsson Harris
    Citation: Pediatric Rheumatology 2021 19:173
  28. Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare hyperinflammatory condition that occurs following SARS-CoV-2 infection. There is a paucity of research describing risk factors, optimal managemen...

    Authors: Jonathan Shabab, Allysen Dubisky, Ambaris Singh, Megan Crippen, Khalid Abulaban and Aileen Aldrich
    Citation: Pediatric Rheumatology 2021 19:172
  29. During the Coronavirus disease 2019 pandemic, ambulatory pediatric rheumatology healthcare rapidly transformed to a mainly telehealth model. However, pediatric patient and caregiver satisfaction with broadly d...

    Authors: Lindsay N. Waqar-Cowles, John Chuo, Pamela F. Weiss, Sabrina Gmuca, Marianna LaNoue and Jon M. Burnham
    Citation: Pediatric Rheumatology 2021 19:170
  30. Precision health in adolescents relies on the successful collection of data and biospecimens from an adequately sized sample of cases and comparison group(s), often healthy controls, to answer the research que...

    Authors: Kimberly A. Lewis, Shelby Brooks, Ruy Carrasco, Patricia Carter, Alexandra Garcia, Jennifer Chiou, Christina Nguyen, Ambreen Rana, Sharon A. Brown, Stefano Tiziani and Nico Osier
    Citation: Pediatric Rheumatology 2021 19:169
  31. Childhood Polyarteritis nodosa (PAN) is a systemic vasculitis with necrotizing inflammation of medium- and small-sized arteries. Disease evolution may be severe and refractory to standard treatment including p...

    Authors: Margaux Boistault, Mireia Lopez Corbeto, Pierre Quartier, Laura Berbel Arcobé, Ariadna Carsi Durall and Florence A. Aeschlimann
    Citation: Pediatric Rheumatology 2021 19:168
  32. The objective of this work was to describe magnetic resonance imaging (MRI) changes over time in inflammatory and structural lesions at the sacroiliac joint (SIJ) in children with spondyloarthritis (SpA) expos...

    Authors: Timothy G. Brandon, Rui Xiao, Rosemary G. Peterson, Nancy A. Chauvin, Michael L. Francavilla, David M. Biko, Dax G. Rumsey, Matthew L. Stoll and Pamela F. Weiss
    Citation: Pediatric Rheumatology 2021 19:167
  33. Juvenile Idiopathic Arthritis (JIA) is a group of chronic heterogenous disorders that manifests as joint inflammation in patients aged <16 years. Globally, approximately 3 million children and young adults are...

    Authors: Sulaiman M. Al-Mayouf, Muna Al Mutairi, Kenza Bouayed, Sara Habjoka, Djohra Hadef, Hala M. Lotfy, Cristiaan Scott, Elsadeg M. Sharif and Nouran Tahoun
    Citation: Pediatric Rheumatology 2021 19:166
  34. The transition of health care from Pediatric to Adult providers for adolescents and young adults with chronic disease is associated with poor outcomes. Despite the importance of this transition, over 80% of th...

    Authors: Rebecca S. Overbury, Kelly Huynh, John Bohnsack, Tracy Frech and Aimee Hersh
    Citation: Pediatric Rheumatology 2021 19:164
  35. Flares of juvenile idiopathic arthritis (JIA) have been described in the context of various infections. Flares of rheumatic diseases in adults have been described following infection with SARS-CoV-2 in several...

    Authors: Boris Hügle, Manuela Krumrey-Langkammerer and Johannes-Peter Haas
    Citation: Pediatric Rheumatology 2021 19:163
  36. This study aimed to assess the baseline characteristics and clinical outcomes of coronavirus disease 2019 (COVID-19) in pediatric patients with rheumatic and musculoskeletal diseases (RMD) and identify the ris...

    Authors: Daniel Clemente, Clara Udaondo, Jaime de Inocencio, Juan Carlos Nieto, Pilar Galán del Río, Antía García Fernández, Jaime Arroyo Palomo, Javier Bachiller-Corral, Juan Carlos Lopez Robledillo, Claudia Millán Longo, Leticia Leon, Lydia Abasolo and Alina Boteanu
    Citation: Pediatric Rheumatology 2021 19:162
  37. Mevalonate kinase deficiency (MKD) is a rare autoinflammatory condition caused by biallelic loss-of-function (LOF) mutations in mevalonate kinase (MVK) gene encoding the enzyme mevalonate kinase. Patients with MK...

    Authors: Ebun Omoyinmi, Dorota Rowczenio, Neil Sebire, Paul A. Brogan and Despina Eleftheriou
    Citation: Pediatric Rheumatology 2021 19:161

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