- Poster presentation
- Open Access
8.3 Disease patterns in Danish Juvenile Dermatomyositis patients
© Mathiesen et al; licensee BioMed Central Ltd. 2008
- Published: 15 September 2008
- Disease Onset
- Unknown Status
- Retrospective Assessment
Retrospective assessment of disease characteristics and outcome for the Danish cohort of Juvenile Dermatomyositis (JDM) patients, 1977 – 2005.
Evaluation of the Myositis disease activity assessment tool (MYOACT) and Myositis intention to treat activity index (MITAX) as prognostic tools.
Hospital records from Danish JDM patients (1977 – 2005) were reviewed. The parameters of the MYOACT and MITAX were used for the database.
Most frequent symptoms at disease onset
% of patients
Proximal muscle weakness
At the 5-years follow-up 34% were in remission, 30% had ongoing disease and disease- or treatment-induced damage was present in 36%. In the total follow-up period (2–30 years) 3 patients (6%) had died, 68% were in full remission, 13% had ongoing disease and 13% had unknown status.
Most patients had a favourable outcome; however irreversible damage was found in 36% at 5-years follow-up
Baseline predictors of unfavourable disease outcome could not be identified
Due to frequently missing chart data MYOACT and MITAX could not be used as a scoring tool in this retrospective set-up
A clinical long-term follow-up study is warranted and now carried out by the authors.
This article is published under license to BioMed Central Ltd.