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Gastroparesis associated with Juvenile Dermatomyositis
Pediatric Rheumatology volume 6, Article number: P217 (2008)
Gastrointestinal involvement is well recognised in juvenile dermatomyositis (JDM) Dysphagia due to pharyngeal and upper oesophageal dysmotility occurs in 33% of UK patients . Gastrointestinal vasculitis with ulceration and intestinal perforation is also described. There is only one previous report highlighting gastric dysmotility associated with juvenile dermatomyositis .
We present two cases where gastroparesis was associated with JDM and improved with immunosuppression. Clinical features and investigations are summarised in table 1.
Gastric dysmotility may complicate JDM. In both these cases it presented with intractable vomiting and otherwise normal gastrointestinal investigations. Neither had evidence of otherwise active JDM at the time of onset of their vomiting but both responded to immunosuppression.
McCann LJ, Juggins AD, Maillard SM, Wedderburn LR, Davidson JE, Murray KJ, Pilkington CA: Juvenile Dermatomyositis Research Group. The Juvenile Dermatomyositis National Registry and Repository (UK and Ireland)–clinical characteristics of children recruited within the first 5 yr. Rheumatology. 2006, 45 (10): 1255-1260. 10.1093/rheumatology/kel099.
Laskin BL, Choyke P, Keenan GF, Miller FW, Rider LG: Novel gastrointestinal tract manifestations in juvenile dermatomyositis. Journal of Pediatrics. 1999, 135 (3): 371-374. 10.1016/S0022-3476(99)70137-X.
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Martin, N., Davidson, J., Harris, H. et al. Gastroparesis associated with Juvenile Dermatomyositis. Pediatr Rheumatol 6, P217 (2008). https://doi.org/10.1186/1546-0096-6-S1-P217
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