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  1. Review

    Methods for analyzing observational longitudinal prognosis studies for rheumatic diseases: a review & worked example using a clinic-based cohort of juvenile dermatomyositis patients

    Most outcome studies of rheumatic diseases report outcomes ascertained on a single occasion. While single assessments are sufficient for terminal or irreversible outcomes, they may not be sufficiently informat...

    Lily Siok Hoon Lim, Eleanor Pullenayegum, Rahim Moineddin, Dafna D Gladman, Earl D Silverman and Brian M Feldman

    Pediatric Rheumatology 2017 15:18

    Published on: 29 March 2017

  2. Research article

    Missed opportunities for timely diagnosis of pediatric lupus in South Africa: a qualitative study

    Systemic Lupus Erythematosus (SLE) is a serious multisystem autoimmune disease, which is more aggressive in children and people of African descent. In South Africa, pediatric SLE (pSLE) patients are at high ri...

    Laura B. Lewandowski, Melissa H. Watt, Laura E. Schanberg, Nathan M. Thielman and Christiaan Scott

    Pediatric Rheumatology 2017 15:14

    Published on: 23 February 2017

  3. Research article

    Psoriasis and associated variables in classification and outcome of juvenile idiopathic arthritis - an eight-year follow-up study

    To study the impact of psoriasis and features associated with psoriasis on classification and outcome in a population-based follow-up cohort of children with juvenile idiopathic arthritis (JIA).

    Maria Ekelund, Kristiina Aalto, Anders Fasth, Troels Herlin, Susan Nielsen, Ellen Nordal, Suvi Peltoniemi, Marite Rygg, Marek Zak and Lillemor Berntson

    Pediatric Rheumatology 2017 15:13

    Published on: 22 February 2017

  4. Research article

    TLR4 rs41426344 increases susceptibility of rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in a central south Chinese Han population

    The aim of the study was to determine whether polymorphisms in toll-like receptor 4 (TLR4) confer susceptibility to rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in a central south Chinese Han...

    Yan Wang, Lianghui Chen, Fang Li, Meihua Bao, Jie Zeng, Ju Xiang, Huaiqing Luo, Jianming Li and Liang Tang

    Pediatric Rheumatology 2017 15:12

    Published on: 21 February 2017

  5. Short report

    A comparison of three treatment strategies in recent onset non-systemic Juvenile Idiopathic Arthritis: initial 3-months results of the BeSt for Kids-study

    Combination therapy with prednisone or etanercept may induce earlier and/or more improvement in disease activity in Disease Modifying Anti Rheumatic Drug (DMARD) naïve non-systemic Juvenile Idiopathic Arthriti...

    P. C. E. Hissink Muller, D. M. C. Brinkman, D. Schonenberg, Y. Koopman-Keemink, I. C. J. Brederije, W. P. Bekkering, T. W. Kuijpers, M. A. J. van Rossum, L. W. A. van Suijlekom-Smit, J. M. van den Berg, C. F. Allaart and R. ten Cate

    Pediatric Rheumatology 2017 15:11

    Published on: 6 February 2017

  6. Research article

    “HLA-G 3′UTR gene polymorphisms and rheumatic heart disease: a familial study among South Indian population”

    Rheumatic heart disease (RHD) is an autoimmune disease where cross reactive CD4+ T cells are involved in the pathogenesis of valvular damage. Human Leukocyte Antigen-G (HLA-G), an immunosuppressive molecule playi...

    Maheshkumar Poomarimuthu, Sivakumar Elango, Sambath Soundrapandian and Jayalakshmi Mariakuttikan

    Pediatric Rheumatology 2017 15:10

    Published on: 1 February 2017

  7. Research article

    Establishing percentile charts for hip joint capsule and synovial cavity thickness in apparently healthy children

    The usefulness of musculoskeletal ultrasonography (MSUS) in paediatric population is limited by lack of reference values. One of such parameters is hip joint capsule thickness, postulated as an early measure f...

    Zbigniew Żuber, Aleksander Owczarek, Małgorzata Sobczyk, Agata Migas-Majoch, Dorota Turowska-Heydel, Agnieszka Sternal, Justyna Michalczak and Jerzy Chudek

    Pediatric Rheumatology 2017 15:8

    Published on: 31 January 2017

  8. Research article

    Spectrum of paediatric rheumatic diseases in Nigeria

    Paediatric rheumatology service in Sub-Sahara African is virtually not available as there is a shortage of paediatric rheumatologists and other rheumatology health professionals. We aim to describe the clinica...

    Babatunde Hakeem Olaosebikan, Olufemi Oladipo Adelowo, Barakat Adeola Animashaun and Richard Oluyinka Akintayo

    Pediatric Rheumatology 2017 15:7

    Published on: 31 January 2017

  9. Research article

    Endothelial function in children with a history of henoch schonlein purpura

    Although Henoch-Schonlein purpura (HSP) is the most common form of systemic vasculitis in children, the long term effect of HSP on endothelial function is still not clear. The aim of our study was to evaluate ...

    Yonatan Butbul Aviel, Lotem Dafna, Giora Pilar and Riva Brik

    Pediatric Rheumatology 2017 15:3

    Published on: 14 January 2017

  10. Research article

    The spectrum of rheumatic in-patient diagnoses at a pediatric hospital in Kenya

    Pediatric rheumatic diseases are chronic illnesses that can cause considerable disease burden to children and their families. There is limited epidemiologic data on these diseases in East Africa. The aim of th...

    Angela Migowa, Inés Colmegna, Carol Hitchon, Eugene Were, Evelyn Ng’ang’a, Thomas Ngwiri, John Wachira, Sasha Bernatsky and Rosie Scuccimarri

    Pediatric Rheumatology 2017 15:4

    Published on: 14 January 2017

  11. Research article

    Childhood Arthritis and Rheumatology Research Alliance consensus clinical treatment plans for juvenile dermatomyositis with skin predominant disease

    Juvenile dermatomyositis (JDM) is the most common form of the idiopathic inflammatory myopathies in children. A subset of children have the rash of JDM without significant weakness, and the optimal treatments ...

    Susan Kim, Philip Kahn, Angela B. Robinson, Bianca Lang, Andrew Shulman, Edward. J. Oberle, Kenneth Schikler, Megan Lea Curran, Lilliana Barillas-Arias, Charles H. Spencer, Lisa G. Rider and Adam M. Huber

    Pediatric Rheumatology 2017 15:1

    Published on: 11 January 2017

  12. Research article

    Disease status, reasons for discontinuation and adverse events in 1038 Italian children with juvenile idiopathic arthritis treated with etanercept

    Data from routine clinical practice are needed to further define the efficacy and safety of biologic medications in children with juvenile idiopathic arthritis (JIA). The aim of this analysis was to investigat...

    Sara Verazza, Sergio Davì, Alessandro Consolaro, Francesca Bovis, Antonella Insalaco, Silvia Magni-Manzoni, Rebecca Nicolai, Denise Pires Marafon, Fabrizio De Benedetti, Valeria Gerloni, Irene Pontikaki, Francesca Rovelli, Rolando Cimaz, Achille Marino, Francesco Zulian, Giorgia Martini…

    Pediatric Rheumatology 2016 14:68

    Published on: 20 December 2016

  13. Research article

    Evidence-based decision support for pediatric rheumatology reduces diagnostic errors

    The number of trained specialists world-wide is insufficient to serve all children with pediatric rheumatologic disorders, even in the countries with robust medical resources. We evaluated the potential of dia...

    Michael M. Segal, Balu Athreya, Mary Beth F. Son, Irit Tirosh, Jonathan S. Hausmann, Elizabeth Y. N. Ang, David Zurakowski, Lynn K. Feldman and Robert P. Sundel

    Pediatric Rheumatology 2016 14:67

    Published on: 13 December 2016

  14. Research article

    Fatigue in patients with Juvenile Idiopathic Arthritis: relationship to perceived health, physical health, self-efficacy, and participation

    Fatigue is common in patients with JIA and affects daily life negatively. We assessed the presence and severity of fatigue in patients with JIA, including factors presumed associated with fatigue (e.g., diseas...

    Wineke Armbrust, Otto H. T. M. Lelieveld, Jolanda Tuinstra, Nico M. Wulffraat, G. J. F. Joyce Bos, Jeannette Cappon, Marion A. J. van Rossum, Pieter J. J. Sauer and Mariët Hagedoorn

    Pediatric Rheumatology 2016 14:65

    Published on: 6 December 2016

  15. Research article

    Monitoring change in volume of calcifications in juvenile idiopathic inflammatory myopathy: a pilot study using low dose computed tomography

    Dystrophic calcifications may occur in patients with J uvenile Idiopathic Inflammatory Myopathy (JIIM) as well as other connective tissue and metabolic diseases, but a reliable method of measuring the volume o...

    Maria Ibarra, Cynthia Rigsby, Gabrielle A. Morgan, Christina L. Sammet, Chiang-Ching Huang, Dong Xu, Ira N. Targoff and Lauren M. Pachman

    Pediatric Rheumatology 2016 14:64

    Published on: 29 November 2016

  16. Case Report

    Juvenile arthritis caused by a novel FAMIN (LACC1) mutation in two children with systemic and extended oligoarticular course

    The pathophysiological origin of juvenile idiopathic arthritis (JIA) is largely unknown. However, individuals with presumably pathogenic mutations in FAMIN have been reported, associating this gene with a rare su...

    Tilmann Kallinich, Anne Thorwarth, Sae-Lim von Stuckrad, Angela Rösen-Wolff, Hella Luksch, Patrick Hundsdoerfer, Kirsten Minden and Peter Krawitz

    Pediatric Rheumatology 2016 14:63

    Published on: 24 November 2016

  17. Research article

    Assessment of left atrial mechanical functions and atrial electromechanical delay in Juvenile idiopathic arthritis by tissue Doppler echocardiography

    Juvenile idiopathic arthritis (JIA) is a systemic chronic inflammatory disease. Studies using tissue Doppler imaging (TDI) for the evaluation of cardiac functions of children with JIA are limited. Thus, this s...

    Azza Z. El Eraky, Nesrin M. Handoka, Mona Sayed Ghaly, Samah Ismail Nasef, Nahed A. Eldahshan, Ahmed M. Ibrahim and Sherein Shalaby

    Pediatric Rheumatology 2016 14:62

    Published on: 24 November 2016

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