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  1. Content type: Review

    The Paediatric Rheumatology European Society (PReS) has over many years, developed a portfolio of educational activities to address increasing educational needs of workforce and support young clinicians to acq...

    Authors: Helen E. Foster, Jelena Vojinovic, Tamas Constantin, Alberto Martini, Pavla Dolezalova, Yosef Uziel, E.M.D Smith, Lovro Lamot, Carine Wouters, Tadej Avcin and Nico Wulffraat

    Citation: Pediatric Rheumatology 2018 16:77

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  2. Content type: Research article

    Patient recruitment can be very challenging in paediatric studies, especially in relatively uncommon conditions, such as juvenile idiopathic arthritis (JIA). However, involving children and young people (CYP) ...

    Authors: Frances C. Sherratt, Louise Roper, Simon R. Stones, Flora McErlane, Matthew Peak, Michael W. Beresford, Helen Foster, Athimalaipet V. Ramanan, Madeleine Rooney, Eileen Baildam and Bridget Young

    Citation: Pediatric Rheumatology 2018 16:76

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  3. Content type: Research article

    Non-adherence is a prevalent and modifiable issue in juvenile idiopathic arthritis (JIA) that currently lacks provider-based intervention. Education surrounding disease status is one way in which families rema...

    Authors: Leslie A. Favier, Tracy V. Ting and Avani C. Modi

    Citation: Pediatric Rheumatology 2018 16:75

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  4. Content type: Research article

    To understand the demographics, clinical features and treatment outcomes of Chronic Non-bacterial Osteitis (CNO) from three tertiary paediatric rheumatology services in the United Kingdom.

    Authors: Chandrika S. Bhat, Catriona Anderson, Aoibhinn Harbinson, Liza J. McCann, Marion Roderick, Adam Finn, Joyce E. Davidson and Athimalaipet V. Ramanan

    Citation: Pediatric Rheumatology 2018 16:74

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  5. Content type: Research article

    To quantify the impact of inflammatory brain diseases in the pediatric population on health-related quality of life, including the subdomains of physical, emotional, school and social functioning.

    Authors: Elina Liu, Marinka Twilt, Pascal N. Tyrrell, Anastasia Dropol, Shehla Sheikh, Mark Gorman, Susan Kim, David A. Cabral, Rob Forsyth, Heather Van Mater, Suzanne Li, Adam M. Huber, Elizabeth Stringer, Eyal Muscal, Dawn Wahezi, Mary Toth…

    Citation: Pediatric Rheumatology 2018 16:73

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  6. Content type: Research article

    To follow up the refractory juvenile dermatomyositis (JDM) with autologous hematopoietic stem cell transplantation (AHSCT) in a long time and to investigate whether AHSCT is effective and safe to treat refract...

    Authors: Jia Zhu, Gaixiu Su, Jianming Lai, Boya Dong, Min Kang, Shengnan Li, Zhixuan Zhou and Fengqi Wu

    Citation: Pediatric Rheumatology 2018 16:72

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  7. Content type: Research article

    Henoch-Schonlein purpura (HSP) is a small vessel vasculitis that is characterized by non-thrombocytopenic purpura, abdominal pain, arthritis, and glomerulonephritis. Typically, HSP is self-limited requiring on...

    Authors: Courtney B. Crayne, Esraa Eloseily, Melissa L. Mannion, Saji P. Azerf, Peter Weiser, Timothy Beukelman, Matthew L. Stoll, Daniel I. Feig, T. Prescott Atkinson and Randy Quentin Cron

    Citation: Pediatric Rheumatology 2018 16:71

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  8. Content type: Research article

    The advent of new treatments for Juvenile Idiopathic Arthritis (JIA) has prompted interest in systematically studying the outcomes of patients treated in the ‘modern era’. Such data provide both benchmarks for...

    Authors: Georgina Tiller, Joanne Buckle, Roger Allen, Jane Munro, Peter Gowdie, Angela Cox and Jonathan Akikusa

    Citation: Pediatric Rheumatology 2018 16:69

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  9. Content type: Research article

    Juvenile Idiopathic Arthritis (JIA) affects over 1000 children and adolescents in Ireland, potentially impacting health-related quality-of-life. Accessible self-management strategies, including Internet-based int...

    Authors: Grace O’Sullivan, Siobhán O’Higgins, Line Caes, Sophia Saetes, Brian E. McGuire and Jennifer Stinson

    Citation: Pediatric Rheumatology 2018 16:68

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  10. Content type: Research article

    To reduce treatment variability and facilitate comparative effectiveness studies, the Childhood Arthritis and Rheumatology Research Alliance (CARRA) published consensus treatment plans (CTPs) including one for...

    Authors: Jennifer C Cooper, Kelly Rouster-Stevens, Tracey B Wright, Joyce J Hsu, Marisa S Klein-Gitelman, Stacy P Ardoin, Laura E Schanberg, Hermine I Brunner, B Anne Eberhard, Linda Wagner-Weiner, Jay Mehta, Kathleen Haines, Deborah K McCurdy, Thomas A Phillips, Zhen Huang and Emily von Scheven

    Citation: Pediatric Rheumatology 2018 16:65

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  11. Content type: Research article

    Arthritis in childhood can be associated with muscle weakness around affected joints, low bone mass and low bone strength. Exercise is recognized as an important part of management of children with juvenile id...

    Authors: Kristin M. Houghton, Heather M. Macdonald, Heather A. McKay, Jaime Guzman, Ciarán Duffy and Lori Tucker

    Citation: Pediatric Rheumatology 2018 16:67

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  12. Content type: Research article

    Children and adolescents with juvenile idiopathic arthritis (JIA) are less physically active than their healthy peers and are at high risk of missing out on the general health benefits of physical activity. We...

    Authors: Liane D. Heale, Saunya Dover, Y. Ingrid Goh, Victoria A. Maksymiuk, Greg D. Wells and Brian M. Feldman

    Citation: Pediatric Rheumatology 2018 16:66

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  13. Content type: Research article

    Knowledge about objectively measured levels of physical activity (PA) and PA participation (included facilitators and barriers for PA) in patients with juvenile idiopathic arthritis (JIA) diagnosed in the era ...

    Authors: Kristine Risum, Bjørge Herman Hansen, Anne Marit Selvaag, Øyvind Molberg, Hanne Dagfinrud and Helga Sanner

    Citation: Pediatric Rheumatology 2018 16:64

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  14. Content type: Research article

    Adherence to treatment for chronic diseases is lower in children than in adults, less extensively studied in children and is associated with multiple related factors. The aim of this study is to perform a desc...

    Authors: Livia de Freitas Keppeke, Juliana Molina, Vanessa Bugni Miotto e Silva, Maria Teresa de Sande e Lemos Ramos Ascensão Terreri, Gerson Dierley Keppeke, Teresa Helena Schoen and Claudio Arnaldo Len

    Citation: Pediatric Rheumatology 2018 16:63

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  15. Content type: Research article

    Morbidity and mortality in childhood onset systemic lupus erythematosus (SLE) is more severe than adult onset SLE. Long-term follow up is needed to determine the prognosis. The objectives of this study are to ...

    Authors: Pondtip Jongvilaikasem, Edward B. McNeil, Pornsak Dissaneewate and Prayong Vachvanichsanong

    Citation: Pediatric Rheumatology 2018 16:62

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  16. Content type: Case Report

    We previously described an endogamous Pakistani kindred in whom we identified a novel homozygous missense mutation in the PRKCD gene encoding for protein kinase C δ (PKCδ) as a cause of monogenic systemic lupus e...

    Authors: Linda Lei, Sabina Muhammad, Muthana Al-Obaidi, Neil Sebire, Iek Leng Cheng, Despina Eleftheriou and Paul Brogan

    Citation: Pediatric Rheumatology 2018 16:61

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  17. Content type: Research article

    Diagnosis of Periodic Fever, Aphthous stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) syndrome is currently based on the modified Marshall’s criteria, but no validated evidence based classification crite...

    Authors: Federica Vanoni, Roberta Caorsi, Sandra Aeby, Marie Cochard, Jordi Antón, Stefan Berg, Riva Brik, Pavla Dolezalova, Isabelle Koné-Paut, Benedicte Neven, Seza Ozen, Pascal Pillet, Silvia Stojanov, Carine Wouters, Marco Gattorno and Michaël Hofer

    Citation: Pediatric Rheumatology 2018 16:60

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  18. Content type: Research article

    Physical activity is essential for ensuring optimal physical function and fitness in children with juvenile idiopathic arthritis (JIA). Although exercise intervention trials informed current clinical practice,...

    Authors: Joanie Sims-Gould, Douglas L. Race, Heather Macdonald, Kristin M. Houghton, Ciarán M. Duffy, Lori B. Tucker and Heather A. McKay

    Citation: Pediatric Rheumatology 2018 16:59

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  19. Content type: Research article

    Musculoskeletal Ultrasonography (MSUS) is an important tool for the clinical assessment in Juvenile Idiopathic Arthritis (JIA). The objective of this study was to evaluate the reliability of MSUS to detect ele...

    Authors: Lucio Ventura-Ríos, Enrique Faugier, Laura Barzola, L. B. De la Cruz-Becerra, Guadalupe Sánchez-Bringas, Andrés Rodríguez García, Rocío Maldonado, Johannes Roth and Cristina Hernández-Díaz

    Citation: Pediatric Rheumatology 2018 16:58

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  20. Content type: Review

    Research on Juvenile Idiopathic Arthritis (JIA) should support patients, caregivers/parents (carers) and clinicians to make important decisions in the consulting room and eventually to improve the lives of pat...

    Authors: Casper G. Schoemaker, Wineke Armbrust, Joost F. Swart, Sebastiaan J. Vastert, Jorg van Loosdregt, Anouk Verwoerd, Caroline Whiting, Katherine Cowan, Wendy Olsder, Els Versluis, Rens van Vliet, Marlous J. Fernhout, Sanne L. Bookelman, Jeannette Cappon, J. Merlijn van den Berg, Ellen Schatorjé…

    Citation: Pediatric Rheumatology 2018 16:57

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  21. Content type: Research article

    Accumulated damage is an important prognostic factor in systemic lupus erythematous. However, the pattern of disease damage and its risk factors have not been well studied in childhood-onset systemic lupus ery...

    Authors: Jacqueline K. K. Sit and Winnie K. Y. Chan

    Citation: Pediatric Rheumatology 2018 16:56

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  22. Content type: Case Report

    As one kind of osteochondrodysplasia, progressive pseudorheumatoid dysplasia (PPD) is also known as spondyloepiphyseal dysplasia tarda with progressive arthropathy or arthropathy progressive pseudorheumatoid o...

    Authors: Wenji Chen, Shiyan Mo, Gui Luo, Yanyan Wang, Xiaohu Deng, Jian Zhu and Wei Zhao

    Citation: Pediatric Rheumatology 2018 16:55

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  23. Content type: Case Report

    Henoch-Schonlein Purpura (HSP) is one of the most common vasculitides of childhood, with 10–20 cases per 100,000 children. It frequently occurs following an infectious trigger and involves IgA and C3 depositio...

    Authors: Jessica L. Bloom, Jeffrey R. Darst, Lori Prok and Jennifer B. Soep

    Citation: Pediatric Rheumatology 2018 16:54

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  24. Content type: Correction

    Following publication of the original article [1], the authors reported an error in the data of their article: one girl was by mistake scored as a boy. The authors have made new analyses of the corrected data....

    Authors: Veronica Lundberg, Viveca Lindh, Catharina Eriksson, Solveig Petersen and Eva Eurenius

    Citation: Pediatric Rheumatology 2018 16:53

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    The original article was published in Pediatric Rheumatology 2012 10:33

  25. Content type: Research article

    There is a paucity of data on the ocular outcomes in paediatric non-infectious uveitis since the introduction of the biologic agents. The purpose of this study was to outline the clinical characteristics of ch...

    Authors: Megan Cann, Athimalaipet V. Ramanan, Andrew Crawford, Andrew D. Dick, Sarah L. N. Clarke, Fatima Rashed and Catherine M. Guly

    Citation: Pediatric Rheumatology 2018 16:51

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  26. Content type: Research article

    In 2008 a clinical transition pathway for young people with juvenile-onset rheumatic and musculoskeletal diseases (jRMD) aiming at improving transitional care was instituted. Historical data on drop-out rate i...

    Authors: Margot Walter, Sylvia Kamphuis, Philomine van Pelt, Annemarie de Vroed and Johanna M. W. Hazes

    Citation: Pediatric Rheumatology 2018 16:50

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  27. Content type: Case Report

    Chronic recurrent multifocal osteomyelitis (CRMO) is a rare auto-inflammatory bone disorder that primarily affects young girls, with a mean age of 10 years at onset. Generally, it is a self-limited disease. Ho...

    Authors: Ausra Snipaitiene, Rima Sileikiene, Justina Klimaite, Edita Jasinskiene, Rimantas Uktveris and Lina Jankauskaite

    Citation: Pediatric Rheumatology 2018 16:49

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  28. Content type: Research article

    Kawasaki disease (KD) is an acute febrile systemic vasculitis that affects small and medium blood vessels. Intensified treatments for the most severely affected patients have been proposed recently, and the ea...

    Authors: Dima Chbeir, Jean Gaschignard, Ronan Bonnefoy, Constance Beyler, Isabelle Melki, Albert Faye and Ulrich Meinzer

    Citation: Pediatric Rheumatology 2018 16:48

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  29. Content type: Research article

    Little is known about the chronicity of orofacial symptoms and how this influences the oral health-related quality of life in juvenile idiopathic arthritis (JIA). Therefore, our objectives were to study the lo...

    Authors: Hanna Rahimi, Marinka Twilt, Troels Herlin, Lynn Spiegel, Thomas Klit Pedersen, Annelise Küseler and Peter Stoustrup

    Citation: Pediatric Rheumatology 2018 16:47

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  30. Content type: Review

    Specialized research networks are essential to achieve drug approvals for rare pediatric diseases. Such networks help realize the potential of global legislation enacted upon the recognition that most children...

    Authors: Hermine I. Brunner, Lisa G. Rider, Daniel J. Kingsbury, Dominic Co, Rayfel Schneider, Ellen Goldmuntz, Karen B. Onel, Edward H. Giannini and Daniel J. Lovell

    Citation: Pediatric Rheumatology 2018 16:45

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  31. Content type: Review

    Conventional pharmacological therapies for the treatment of juvenile idiopathic arthritis (JIA) consist of non-biological, disease-modifying antirheumatic drugs, among which methotrexate (MTX) is the most comm...

    Authors: Giovanna Ferrara, Greta Mastrangelo, Patrizia Barone, Francesco La Torre, Silvana Martino, Giovanni Pappagallo, Angelo Ravelli, Andrea Taddio, Francesco Zulian and Rolando Cimaz

    Citation: Pediatric Rheumatology 2018 16:46

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  32. Content type: Research article

    To understand the relationship between regulatory B cells (Bregs) and juvenile idiopathic arthritis (JIA), we analyzed the percentages of Bregs and their function in peripheral blood (PB) and synovial fluid (S...

    Authors: Qianzi Zhao and Lawrence K. Jung

    Citation: Pediatric Rheumatology 2018 16:44

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  33. Content type: Research article

    Juvenile idiopathic arthritis (JIA) is an inflammatory arthritis of unknown etiology, which lasts for greater than 6 weeks with onset before 16 years of age. JIA is the most common chronic rheumatic disease in...

    Authors: Daniel J. Lovell, Jason A. Dare, Megan Francis-Sedlak, Julie Ball, Brian D. LaMoreaux, Emily Von Scheven, Adam Reinhardt, Rita Jerath, Oral Alpan, Ramesh Gupta, Donald Goldsmith, Andrew Zeft, Henry Naddaf, Beth Gottlieb, Lawrence Jung and Robert J. Holt

    Citation: Pediatric Rheumatology 2018 16:41

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  34. Content type: Research article

    Juvenile dermatomyositis (JDM) is the most common inflammatory myopathy in childhood and a major cause of morbidity among children with pediatric rheumatic diseases. The management of JDM is very heterogeneous...

    Authors: Claas H. Hinze, Prasad T. Oommen, Frank Dressler, Andreas Urban, Frank Weller-Heinemann, Fabian Speth, Elke Lainka, Jürgen Brunner, Heike Fesq, Dirk Foell, Wolfgang Müller-Felber, Ulrich Neudorf, Christoph Rietschel, Tobias Schwarz, Ulrike Schara and Johannes-Peter Haas

    Citation: Pediatric Rheumatology 2018 16:40

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  35. Content type: Research article

    Juvenile Dermatomyositis (JDM) is a rare pediatric autoimmune disease with broad variations of the individual course. Data on the optimal management are mostly lacking. Currently treatment decisions are often ...

    Authors: Claas H. Hinze, Fabian Speth, Prasad T. Oommen and Johannes-Peter Haas

    Citation: Pediatric Rheumatology 2018 16:38

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  36. Content type: Research article

    Inflammatory effector T cells trigger inflammation despite increased numbers of Treg cells in the synovial joint of patients suffering from juvenile idiopathic arthritis (JIA). The cAMP response element (CREM)...

    Authors: Kim Ohl, Helge Nickel, Halima Moncrieffe, Patricia Klemm, Anja Scheufen, Dirk Föll, Viktor Wixler, Angela Schippers, Norbert Wagner, Lucy R. Wedderburn and Klaus Tenbrock

    Citation: Pediatric Rheumatology 2018 16:39

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  37. Content type: Research article

    Bisphosphonates are recommended for use as first-line therapy for the prevention and treatment of glucocorticoid-induced osteoporosis in adults. However, the appropriate usage of bisphosphonates for the preven...

    Authors: Yuzaburo Inoue, Kanako Mitsunaga, Takeshi Yamamoto, Koki Chiba, Fumiya Yamaide, Taiji Nakano, Yoshinori Morita, Akiko Yamaide, Shuichi Suzuki, Takayasu Arima, Ken-ichi Yamaguchi, Minako Tomiita, Naoki Shimojo and Yoichi Kohno

    Citation: Pediatric Rheumatology 2018 16:36

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  38. Content type: Short Report

    To assess reliability of the two indexes of Localized Scleroderma Cutaneous Assessment Tool (LoSCAT), the modified Localized Scleroderma Skin Severity Index (mLoSSI) and the Localized Scleroderma Skin Damage I...

    Authors: Anna Agazzi, Gloria Fadanelli, Fabio Vittadello, Francesco Zulian and Giorgia Martini

    Citation: Pediatric Rheumatology 2018 16:37

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  39. Content type: Research article

    Involving people of all ages in health research is now widely advocated. To date, no studies have explored whether and how young people with chronic rheumatic conditions want to be involved in influencing heal...

    Authors: Suzanne Parsons, Wendy Thomson, Katharine Cresswell, Bella Starling and Janet E. McDonagh

    Citation: Pediatric Rheumatology 2018 16:35

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  40. Content type: Review

    Vitamin D has been implicated in the pathogenesis of autoimmune diseases. While the roles of vitamin D in other autoimmune diseases have been investigated, less is known about the role of vitamin D in chronic ...

    Authors: Sarah L. Finch, Alan M. Rosenberg and Hassan Vatanparast

    Citation: Pediatric Rheumatology 2018 16:34

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  41. Content type: Research article

    The pathogenesis of Kawasaki disease are still not well understood. It was designed to investigate the relationship between adipokines including chemerin, omentin-1, adiponectin and acute Kawasaki disease.

    Authors: Xin-yan Zhang, Ting-ting Yang, Xiu-fen Hu, Yu Wen, Feng Fang and Hui-ling Lu

    Citation: Pediatric Rheumatology 2018 16:33

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  42. Content type: Research article

    To compare final height to mid-parental target height among adults with childhood-onset systemic lupus erythematosus (cSLE) versus adult-onset SLE (aSLE), and to evaluate the impact of age at SLE onset on fina...

    Authors: Merav Heshin-Bekenstein, Liat Perl, Aimee O. Hersh, Emily von Scheven, Ed Yelin, Laura Trupin, Jinoos Yazdany and Erica F. Lawson

    Citation: Pediatric Rheumatology 2018 16:30

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  43. Content type: Correction

    Following publication of the original article [1], the authors reported that the names of two institutional authors – EUROFEVER and the Paediatric Rheumatology International Trials Organisation (PRINTO) – had ...

    Authors: Romina Gallizzi, Caterina Pidone, Luca Cantarini, Martina Finetti, Marco Cattalini, Giovanni Filocamo, Antonella Insalaco, Donato Rigante, Rita Consolini, Maria Cristina Maggio, Adele Civino, Silvana Martino, Alma Nunzia Olivieri, Giovanna Fabio, Serena Pastore, Angela Mauro…

    Citation: Pediatric Rheumatology 2018 16:29

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    The original article was published in Pediatric Rheumatology 2017 15:84

  44. Content type: Research article

    A standardized set of quality measures for juvenile idiopathic inflammatory myopathies (JIIM) is not in use. Discordance has been shown between the importance ascribed to quality measures between patients and ...

    Authors: Heather O. Tory, Ruy Carrasco, Thomas Griffin, Adam M. Huber, Philip Kahn, Angela Byun Robinson, David Zurakowski and Susan Kim

    Citation: Pediatric Rheumatology 2018 16:28

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