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  1. Enthesitis/spondylitis-related arthritis (ERA) is a type of juvenile idiopathic arthritis (JIA) frequently associated with HLA-B27. In sub-Saharan Africa, HLA-B27-positive ERA hasn’t been the subject of a spec...

    Authors: Mounib M. Sabounji, Aïssatou Ndiaye and Saïdou Diallo
    Citation: Pediatric Rheumatology 2024 22:31
  2. Stress in patients with Juvenile Idiopathic Arthritis (JIA) has been found to be associated with orofacial pain, psychological distress, jaw dysfunction and loss of daily activities in a cross-sectional study....

    Authors: Alexandra Dimitrijevic Carlsson, Kerstin Wahlund, Erik Kindgren, Martina Frodlund and Per Alstergren
    Citation: Pediatric Rheumatology 2024 22:30
  3. Eosinophilic fasciitis (EF) is a rare disease characterized by skin induration and musculoskeletal abnormalities. Diagnostic criteria for EF are based on adult populations. There is a need to expand the litera...

    Authors: Leigh A. Stubbs, Oluwaseun Ogunbona, Emily Beil, Vibha Szafron, Adekunle Adesina, Sara Anvari, Jamie Lai, Andrea Ramirez, Matthew G. Ditzler and Marietta DeGuzman
    Citation: Pediatric Rheumatology 2024 22:29
  4. A structured transition of adolescents and young adults with chronic autoinflammatory and autoimmune disorders from the pediatric to the adult health care system is important. To date, data on the time, proces...

    Authors: Daniela Choukair, Christian Patry, Ronny Lehmann, Dorothea Treiber, Georg F. Hoffmann, Corinna Grasemann, Normi Bruck, Reinhard Berner, Peter Burgard, Hanns-Martin Lorenz and Burkhard Tönshoff
    Citation: Pediatric Rheumatology 2024 22:28
  5. Authors: Oluwatunmise A. Fawole, Michelle V. Reed, Julia G. Harris, Aimee Hersh, Martha Rodriguez, Karen Onel, Erica Lawson, Tamar Rubinstein, Kaveh Ardalan, Esi Morgan, Anne Paul, Judy Barlin, R. Paola Daly, Mitali Dave, Shannon Malloy, Shari Hume…
    Citation: Pediatric Rheumatology 2024 22:27

    The original article was published in Pediatric Rheumatology 2021 19:19

  6. There is a growing interest concerning the relationship between obesity and several medical conditions and inflammation. Nevertheless, there is a lack of studies regarding body mass index (BMI) among patients ...

    Authors: Anna-Kaisa Tuomi, Katariina Rebane, Ellen Dalen Arnstad, Lillemor Berntson, Anders Fasth, Mia Glerup, Troels Herlin, Hannu Kautiainen, Ellen Nordal, Suvi Peltoniemi, Marite Rygg, Veronika Rypdal, Marek Zak and Kristiina Aalto
    Citation: Pediatric Rheumatology 2024 22:25
  7. Germline heterozygous gain-of-function (GOF) mutations in the PIK3CD gene lead to a rare primary immunodeficiency disease known as activated phosphoinositide 3-kinase (PI3K) δ syndrome type 1(APDS1). Affected pat...

    Authors: Peiwei Zhao, Juan Huang, Huicong Fu, Jiali Xu, Tianhong Li, Xiankai Zhang, Qingjie Meng, Lei Zhang, Li Tan, Wen Zhang, Hebin Chen, Xiaoxia Lu, Yan Ding and Xuelian He
    Citation: Pediatric Rheumatology 2024 22:24
  8. Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology that affects infants and young children but is extremely rare in neonates, especially afebrile KD. We present a case of KD without feve...

    Authors: Mingjun Shen, Die Liu, Fang Ye, Jing Zhang and Jun Wang
    Citation: Pediatric Rheumatology 2024 22:23
  9. Juvenile Idiopathic Arthritis (JIA) Associated Uveitis (JIA-U) remains one of the most serious complications of JIA in children. Historically, pediatric JIA is diagnosed by an Optometrist or Ophthalmologist; h...

    Authors: Kaleo Ede, Michael Shishov, Elisa Wershba, Nikita Goswami, Sabrina Gorry, Malin Joseph, Lucia Mirea and James O’Neil
    Citation: Pediatric Rheumatology 2024 22:22
  10. H Syndrome is a rare genetic condition caused by biallelic pathogenic variants in the SLC29A3 gene. It is characterized by a wide range of clinical manifestations, many of which are related to the immune-rheum...

    Authors: Alessandra Tesser, Erica Valencic, Valentina Boz, Gianluca Tornese, Serena Pastore, Manuela Zanatta and Alberto Tommasini
    Citation: Pediatric Rheumatology 2024 22:21
  11. The defective clearance of apoptotic bodies in juvenile-onset systemic lupus erythematosus (jSLE) potentially leads to the persistence of autoreactive lymphocytes and the perpetuation of the autoimmune respons...

    Authors: Eman Eissa, Rania Kandil, Dalia Dorgham, Raghda Ghorab and Naglaa Kholoussi
    Citation: Pediatric Rheumatology 2024 22:20
  12. Hypertension caused by vascular Behcet’s disease (BD) is an important prognostic factor of paediatric BD. However, much less is known about its clinical features. The objective of this study was to investigate...

    Authors: Xinning Wang, Zhixuan Zhou, Jianguo Li, Gaixiu Su and Xiaohui Li
    Citation: Pediatric Rheumatology 2024 22:19
  13. Systemic juvenile idiopathic arthritis (SJIA) is a form of childhood arthritis with clinical features such as fever, lymphadenopathy, arthritis, rash, and serositis. It seriously affects the growth and develop...

    Authors: Pan Ding, Yi Du, Xinyue Jiang, Huajian Chen and Li Huang
    Citation: Pediatric Rheumatology 2024 22:18
  14. Childhood systemic lupus erythematosus (cSLE) has been considered as a polygenic autoimmune disease; however, a monogenic lupus-like phenotype is emerging with the recent recognition of several related novel h...

    Authors: Patricia Morán-Álvarez, Alessandra Gianviti, Francesca Diomedi-Camassei, Monia Ginevrino, Fabrizio de Benedetti and Claudia Bracaglia
    Citation: Pediatric Rheumatology 2024 22:17
  15. Overlap autoimmune syndromes (OAS) and mixed connective tissue disease (MCTD) are rare in children. We performed a retrospective, longitudinal and descriptive study of Afro-Caribbean patients from the French W...

    Authors: Arthur Felix, Lindsay Osei, Frederique Delion, Benoit Suzon, Aurore Abel, Moustapha Drame, Yves Hatchuel, Christophe Deligny and Fabienne Louis-Sidney
    Citation: Pediatric Rheumatology 2024 22:13
  16. Currently, the criteria used to classify patients with SJIA are different from those used for AOSD. However, it has been recognized that the existing terms are too narrow, subdividing the Still’s population un...

    Authors: Peter A. Nigrovic, Fabrizio de Benedetti, Yukiko Kimura, Daniel J. Lovell and Sebastiaan J. Vastert
    Citation: Pediatric Rheumatology 2024 21(Suppl 1):114

    This article is part of a Supplement: Volume 21 Supplement 1

  17. Although the introduction of the IL-1 and IL-6 inhibiting biologics in 2012 has revolutionized the treatment and markedly improved outcomes for many patients with SJIA, about 20% of these patients continue to ...

    Authors: Grant Schulert, Sebastiaan J. Vastert and Alexei A. Grom
    Citation: Pediatric Rheumatology 2024 21(Suppl 1):87

    This article is part of a Supplement: Volume 21 Supplement 1

  18. It has been increasingly recognized that there is a subset of patients with refractory systemic JIA, who have failed all available medications and may benefit from HSCT. The increasing experience with HSCT in ...

    Authors: Alexei A. Grom, Scott W. Canna, Rolla F. Abu-Arja, Rashmi Sinha, Luciana Peixoto, Elvira Cannizzaro, Shanmuganathan Chandrakasan, Kyla Driest, Rebecca Marsh, Bénédicte Neven, Karen Onel, Sampath Prahalad, Susan Prockop, Pierre Quartier, Johannes Roth, Grant Schulert…
    Citation: Pediatric Rheumatology 2024 21(Suppl 1):86

    This article is part of a Supplement: Volume 21 Supplement 1

  19. Since IL-18 has recently emerged as a biomarker associated with refractory disease course in SJIA, the focus of the discussion was the feasibility of the biomarker-driven drug development to SJIA. Overall, the...

    Authors: Scott W. Canna and Fabrizio De Benedetti
    Citation: Pediatric Rheumatology 2024 21(Suppl 1):79

    This article is part of a Supplement: Volume 21 Supplement 1

  20. Mevalonate kinase deficiency (MKD) and TNF receptor-associated periodic syndrome (TRAPS) are categorized as systemic autoinflammatory diseases (SAIDs), which are rare diseases characterized by early onset, sev...

    Authors: Yandie Li and Meiping Lu
    Citation: Pediatric Rheumatology 2024 22:11
  21. Studies on prevalence rates of mental comorbidities in patients with juvenile idiopathic arthritis (JIA) have reported varying results and provided limited information on related drugs. The purpose of this stu...

    Authors: Florian Milatz, Katinka Albrecht, Kirsten Minden, Ursula Marschall, Jens Klotsche and Johanna Callhoff
    Citation: Pediatric Rheumatology 2024 22:10
  22. STING-associated vasculopathy with onset in infancy (SAVI) is a rare type I interferonopathy caused by heterozygous variants in the STING gene. In SAVI, STING variants confer a gain-of-function which causes overa...

    Authors: Sophia Weidler, Sarah Koss, Christine Wolf, Nadja Lucas, Jürgen Brunner and Min Ae Lee-Kirsch
    Citation: Pediatric Rheumatology 2024 22:9
  23. Juvenile idiopathic recurrent parotitis (JIRP) in children is a condition characterized with recurrent episodes of idiopathic parotid gland inflammation. Since there are no definitive guidelines for diagnosis ...

    Authors: Farhad Salehzadeh, Rasol Molatefi, Ali Mardi and Negin Nahanmoghaddam
    Citation: Pediatric Rheumatology 2024 22:8
  24. The substantial morbidity and mortality associated with refractory systemic JIA underlies the need for new treatment approaches. However, progress in this area has been limited by the difficulty of enrolling t...

    Authors: Fabrizio de Benedetti, Alexei A. Grom and Hermine Brunner
    Citation: Pediatric Rheumatology 2024 21(Suppl 1):150

    This article is part of a Supplement: Volume 21 Supplement 1

  25. Juvenile idiopathic arthritis (JIA) is a prevalent childhood chronic arthritis, often persisting into adulthood. Effective transitional care becomes crucial as these patients transition from pediatric to adult...

    Authors: Betül Sözeri, Nihal Şahin, Ceyhun Açarı, Pinar Ozge Avar Aydın, Ozge Baba, Esra Bağlan, Sevcan Bakkaloğlu, Sibel Bakırcı, Yelda Bilginer, Burcu Yücel Bozkaya, Şengül Çağlayan, Mustafa Çakan, Figen Çakmak, Taner Coşkuner, Ferhat Demir, Fatma Gül Demirkan…
    Citation: Pediatric Rheumatology 2024 22:7
  26. Juvenile Idiopathic Arthritis (JIA) induces growth disturbances in affected joints. Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis. FLS overexpress bone morphogenetic protein 4 (BMP...

    Authors: Megan M. Simonds, Samuel T. Freer and Anne Marie C. Brescia
    Citation: Pediatric Rheumatology 2024 22:6
  27. In pediatric rheumatic diseases (PRD), adalimumab is dosed using fixed weight-based bands irrespective of methotrexate co-treatment, disease activity (DA) or other factors that might influence adalimumab pharm...

    Authors: Tatjana Welzel, Klervi Golhen, Andrew Atkinson, Verena Gotta, David Ternant, Jasmin B. Kuemmerle-Deschner, Christine Michler, Gilbert Koch, Johannes N. van den Anker, Marc Pfister and Andreas Woerner
    Citation: Pediatric Rheumatology 2024 22:5
  28. A rare case of coronary artery involvement in a child with Systemic Juvenile Idiopathic Arthritis (sJIA) complicated by Macrophage Activation Syndrome (MAS) is reported. The patient initially received an inacc...

    Authors: Lian Zhang, Yanwen Wei, Ningjing Zeng, Lianyu Wang, Xinying Chen, Jinghua Yang and Xiaolan Xiao
    Citation: Pediatric Rheumatology 2024 22:4
  29. Patients with rheumatological diseases are at high risk of developing irreversible fibrotic changes, both articular and extra-articular, as a result of tissue damage caused by the chronic phase of persistent i...

    Authors: Olga Pavlova, Natalia Shevchenko, Sergey Pavlov, Tetiana Holovko and Liudmyla Bogmat
    Citation: Pediatric Rheumatology 2024 22:3
  30. Juvenile Dermatomyositis (JDM) is a rare autoimmune disorder that primarily affects muscles and skin. One of the severe complications associated with JDM is calcinosis, and treating this condition presents sig...

    Authors: Reza Shiari, Mitra Khalili, Vahide Zeinali, Niloufar Shashaani, Mohammad Samami and Foroughossadat Hosseini Moghaddamemami
    Citation: Pediatric Rheumatology 2024 22:2
  31. Common severe back pain due to disc herniation is rare in the paediatric population which involves children under eighteen years of age. Paediatric lumbar disc herniation (LDH) cannot be considered the same di...

    Authors: Wendlassida Joelle Stéphanie Tiendrebeogo/Zabsonre, Denlewende Sylvain Zabsonre, Fulgence Kabore, Abdoulaye Sanou, Yakouba Haro, Inoussa Zoungrana and Dieu-Donné Ouedraogo
    Citation: Pediatric Rheumatology 2024 22:1
  32. With chronic diseases, the responsibility for care transfers to adult clinics at some point. Juvenile idiopathic arthritis (JIA) is the most common persistent rheumatic condition in children. A successful tran...

    Authors: Katriina Mikola, Katariina Rebane, Hannu Kautiainen and Kristiina Aalto
    Citation: Pediatric Rheumatology 2023 21:149

    The Correction to this article has been published in Pediatric Rheumatology 2024 22:14

  33. Adalimumab is currently considered the most efficacious anti-TNFα agent for childhood noninfectious uveitis (NIU). The objective of this study was to define a therapeutic range for adalimumab trough levels in...

    Authors: Jo L. Dehoorne, Helena Groth, Emma Carlé, Ilse De Schrijver, Celine Sys, Patricia Delbeke, Elke O. Kreps, Thomas Renson and Carolien Bonroy
    Citation: Pediatric Rheumatology 2023 21:148
  34. Septic arthritis is an important differential diagnosis of hip joint pain. Joint aspiration analysis is a necessary diagnostic measure for septic arthritis. In order to reduce the need for joint aspiration, we...

    Authors: Seyed Ali Alamdaran, Mohadeseh Taheri-nezhad, Ahmad Nouri, Farzaneh Khoroushi, Mohammad Hasan Aalami, Abdoreza Malek, Arezou Mohtasham and Mohamadreza Alizadeh
    Citation: Pediatric Rheumatology 2023 21:146
  35. Much has been written and spoken about telemedicine since about two decades including an article in this journal at the start of the pandemic. It took a global catastrophe to enforce its usage across the world...

    Authors: Raju Khubchandani, Tadej Avčin and Angelo Ravelli
    Citation: Pediatric Rheumatology 2023 21:145
  36. Due to the paucity of paediatric rheumatologists in Kenya, it is paramount that we explore strategies to bridge clinical care gaps for paediatric rheumatology patients in order to promote early diagnosis, prom...

    Authors: Angela Migowa, Sasha Bernatsky, Anthony K. Ngugi, Helen E. Foster, Peterrock Muriuki, Roselyter M. Riang’a and Stanley Luchters
    Citation: Pediatric Rheumatology 2023 21:144
  37. Juvenile idiopathic arthritis (JIA) is a broad term used to describe arthritis of unknown origin. JIA commonly persists into adulthood, often causing substantial morbidity such as restricted joint function, wh...

    Authors: Yun Liu and Xuemei Tang
    Citation: Pediatric Rheumatology 2023 21:143
  38. The treatment of children with multisystem inflammatory syndrome in children (MIS-C) related to SARS-CoV-2 infection involves immunomodulatory therapies such as IVIG and steroids. Anakinra, an interleukin-1 re...

    Authors: Esra B. Akkoyun, Zachary Most, Harita Katragadda, Andrew Yu, Lorien Nassi, Nicole Oakman, Sarah Ginsburg and Mia Maamari
    Citation: Pediatric Rheumatology 2023 21:141
  39. There is no clear data on the optimal duration of treatment with anti-interleukin-1 drugs in colchicine-resistant familial Mediterranean fever patients, as well as on the dose interval. This study aimed to ass...

    Authors: Gülşah Kavrul Kayaalp, Şengül Çağlayan, Fatma Gül Demirkan, Vafa Guliyeva, Gülçin Otar Yener, Kübra Öztürk, Ferhat Demir, Semanur Özdel, Mustafa Çakan, Hafize Emine Sönmez, Betül Sözeri and Nuray Aktay Ayaz
    Citation: Pediatric Rheumatology 2023 21:140
  40. Patients with systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still’s disease (AOSD) have been under-represented in studies about safety of the COVID-19 immunization. We aimed to inquire about th...

    Authors: Mariana Correia Marques, Subrata Paul, Carol Lake, Ly-Lan Bergeron, Rashmi Sinha, Luciana Peixoto, Marinka Twilt and Michael J. Ombrello
    Citation: Pediatric Rheumatology 2023 21:139
  41. Juvenile Dermatomyositis (JDM) is a rare autoimmune disease characterized by skin and muscle inflammation. The loss of nail fold capillary end row loops (ERL) is evidence of small vessel involvement in JDM. Th...

    Authors: Amer Khojah, Gabrielle Morgan, Marisa S. Klein-Gitelman and Lauren M. Pachman
    Citation: Pediatric Rheumatology 2023 21:137

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