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  1. Pediatric rheumatology faces many challenges due to the shortage of board certified physicians in the field and the imbalance in their geographic distribution. This shortage has required primary care physician...

    Authors: Amy Louise Woodward and Zena Leah Harris
    Citation: Pediatric Rheumatology 2013 11:26
    Content type: Research Published on:

  2. We report two pediatric female patients with systemic lupus erythematosus (SLE) who presented with decreased vision. Both patients were found to have retinal vasculitis and occlusive disease. The first patient...

    Authors: Katherine J Donnithorne, Russell W Read, Robert Lowe, Peter Weiser, Randy Q Cron and Timothy Beukelman
    Citation: Pediatric Rheumatology 2013 11:25
    Content type: Case Report Published on:

  4. Children who take methotrexate for juvenile idiopathic arthritis may experience side effects, including nausea and vomiting, leading to anticipatory nausea in some children, and fear of injections or blood tes...

    Authors: Kathleen Mulligan, Laura Kassoumeri, Angela Etheridge, Halima Moncrieffe, Lucy R Wedderburn and Stanton Newman
    Citation: Pediatric Rheumatology 2013 11:23
    Content type: Research Published on:

  5. The limited availability of pediatric rheumatologists for teaching in pediatric residency programs negatively impacts resident education about rheumatology. At present, there are no educational websites availa...

    Authors: Michelle Batthish, Ereny Bassilious, Rayfel Schneider, Brian M Feldman, Avi Hyman and Shirley ML Tse
    Citation: Pediatric Rheumatology 2013 11:22
    Content type: Research Published on:

  6. Anti-TNF agents have proven efficacy in children with severe juvenile idiopathic arthritis (JIA) who are unresponsive to standard therapy. Therefore pain reduction or elimination could be expected. The aim of ...

    Authors: Johanne Jeppesen Lomholt, Mikael Thastum and Troels Herlin
    Citation: Pediatric Rheumatology 2013 11:21
    Content type: Research Published on:

  8. Limb girdle muscular dystrophy type 2B is a rare subtype of muscular dystrophy, the predominant feature of which is muscle weakness. The disease is caused by an autosomal recessively inherited reduction/absenc...

    Authors: Hannah Jethwa, Thomas S Jacques, Roxanna Gunny, Lucy R Wedderburn, Clarissa Pilkington and Adnan Y Manzur
    Citation: Pediatric Rheumatology 2013 11:19
    Content type: Case Report Published on:

  9. Joint pain and swelling are typical symptoms in children with juvenile idiopathic arthritis (JIA) and these are often related to inflammation of the joint. Juvenile osteochondritis dissecans (JOCD), that is se...

    Authors: Liisa Kröger, Eija Piippo-Savolainen, Erja Tyrväinen, Pekko Penttilä and Heikki Kröger
    Citation: Pediatric Rheumatology 2013 11:18
    Content type: Short Report Published on:

  10. A reduced mouth opening capacity may be one of the first clinical signs of pathological changes in the masticatory system. The aim of this retrospective cross-sectional study was to create age related percenti...

    Authors: Lukas Müller, Hubertus van Waes, Christoph Langerweger, Luciano Molinari and Rotraud K Saurenmann
    Citation: Pediatric Rheumatology 2013 11:17
    Content type: Research Published on:

  11. Nonetheless biologic modifier therapies are available treatment strategies for sight-threatening uveitis in children, the lack of evidence from head-to-head randomized controlled studies limits our understandi...

    Authors: Gabriele Simonini, Andrea Taddio, Marco Cattalini, Roberto Caputo, Cinzia de Libero, Fulvio Parentin, Ilaria Pagnini, Loredana Lepore and Rolando Cimaz
    Citation: Pediatric Rheumatology 2013 11:16
    Content type: Research Published on:

  12. The Editors of Pediatric Rheumatology would like to thank all our reviewers who have contributed to the journal in Volume 10 (2012).

    Authors: Alberto Martini and Charles Spencer
    Citation: Pediatric Rheumatology 2013 11:8
    Content type: Reviewer acknowledgement Published on:

  13. A novel technique for preoperative MRI guided wire localization for targeted surgical excisional biopsy of muscle is described in a pediatric patient with juvenile dermatomyositis (JDM). This technique allows ...

    Authors: Victoria C Tuen, Shannon N Zingula, Christopher Moir, Ann M Reed, Jane M Matsumoto and David A Woodrum
    Citation: Pediatric Rheumatology 2013 11:15
    Content type: Case Report Published on:

  14. To investigate the autoinflammatory hereditary periodic fever syndrome genes MVK and TNFRSF1A, and the NLRP1 and IL1 genes, for association with juvenile idiopathic arthritis (JIA).

    Authors: Anne Hinks, Paul Martin, Susan D Thompson, Marc Sudman, Carmel J Stock, Wendy Thomson, Thomas G Day, Jon Packham, Athimalaipet V Ramanan and Rachelle P Donn
    Citation: Pediatric Rheumatology 2013 11:14
    Content type: Research Published on:

  15. Traditional funding models for public paediatric rheumatology care are typically based on providing medical services for a defined number of clinics per week. Anecdotally there is significant demand by patient...

    Authors: Debi V Feldman, Jo Buckle, Jane E Munro, Roger C Allen and Jonathan D Akikusa
    Citation: Pediatric Rheumatology 2013 11:13
    Content type: Research Published on:

  16. Over the last five years, there have been numerous reports of association of juvenile idiopathic arthritis with single nucleotide polymorphisms (SNPs) at various loci outside the major histocompatibility compl...

    Authors: Justine A Ellis, Raul A Chavez, Angela Pezic, Anne-Louise Ponsonby, Jonathan D Akikusa, Roger C Allen and Jane E Munro
    Citation: Pediatric Rheumatology 2013 11:12
    Content type: Short Report Published on:

  17. Following the introduction of the ILAR criteria for juvenile idiopathic arthritis, juvenile psoriatic arthritis (JPsA) has become a better recognized category within the inflammatory arthritides of childhood. ...

    Authors: Yonatan Butbul Aviel, Pascal Tyrrell, Rayfel Schneider, Sandeep Dhillon, Brian M Feldman, Ronald Laxer, Rotraud K Saurenmann, Lynn Spiegel, Bonnie Cameron, Shirley ML Tse and Earl Silverman
    Citation: Pediatric Rheumatology 2013 11:11
    Content type: Research Published on:

  18. Acute respiratory infections (ARI) are frequent in children and complications can occur in patients with chronic diseases. We evaluated the frequency and impact of ARI and influenza-like illness (ILI) episodes...

    Authors: Luciana M Carvalho, Flávia E de Paula, Rodrigo V D Silvestre, Luciana R Roberti, Eurico Arruda, Wyller A Mello and Virginia P L Ferriani
    Citation: Pediatric Rheumatology 2013 11:10
    Content type: Research Published on:

  19. Chronic arthritis is a common feature of juvenile idiopathic arthritis (JIA) and systemic lupus erythematosus (SLE). It was subsequently discovered that Toll-like receptors (TLRs) are able to upregulate cytokine ...

    Authors: Martina Kirchner, Anja Sonnenschein, Simon Schoofs, Peter Schmidtke, Volker N Umlauf and Wilma Mannhardt-Laakmann
    Citation: Pediatric Rheumatology 2013 11:9
    Content type: Research Published on:

  20. Decreased muscle strength, fitness and well-being are common in children and adolescents with juvenile idiopathic arthritis (JIA) compared to healthy peers. Biological drugs have improved health in children wi...

    Authors: Eva Sandstedt, Anders Fasth, Meta Nyström Eek and Eva Beckung
    Citation: Pediatric Rheumatology 2013 11:7
    Content type: Research Published on:

  21. Idiopathic juvenile osteoporosis (IJO) is a rare condition of poorly understood etiology and pathophysiology that affects otherwise healthy children. This condition is characterized clinically by bone pain and...

    Authors: Justine Bacchetta, Katherine Wesseling-Perry, Vicente Gilsanz, Barbara Gales, Renata C Pereira and Isidro B Salusky
    Citation: Pediatric Rheumatology 2013 11:6
    Content type: Research Published on:

  22. In the following a brief commentary is given on a new European project that aims to provide the European countries with recommendations for the care of children and yound adults with rheumatic diseases. These ...

    Authors: Nico M Wulffraat and Bas Vastert
    Citation: Pediatric Rheumatology 2013 11:5
    Content type: Commentary Published on:

  24. Variations in the treatment of juvenile idiopathic arthritis (JIA) may impact on quality of care. The objective of this study was to identify and compare treatment approaches for JIA in two health care systems.

    Authors: Boris Hugle, Johannes-Peter Haas and Susanne M Benseler
    Citation: Pediatric Rheumatology 2013 11:3
    Content type: Research Published on:

  26. The proximal tibiofibular joint (TFJ) is rarely affected in rheumatic diseases, and we frequently interpret pain of the lateral knee as the result of overuse or trauma. Nonetheless, the TFJ is a synovial joint...

    Authors: Scott W Canna, Nancy A Chauvin and Jon M Burnham
    Citation: Pediatric Rheumatology 2013 11:1
    Content type: Case Report Published on:

  27. This report describes 3 year old girl with the unusual presentation of polyarticular juvenile idiopathic arthritis (JIA) with anti-cyclic citrullinated peptide (anti-CCP) antibodies and a positive rheumatoid f...

    Authors: Kozo Yasui, Sonoko Sakata, Hideaki Ochi, Shinji Itamura, Kenta Hirai, Mieko Takenaka, Osamu Mitani, Kazunori Ogawa and Kuniaki Iyoda
    Citation: Pediatric Rheumatology 2012 10:41
    Content type: Case Report Published on:

  28. Many children with sJIA may have a delayed onset of arthritis and so fail to fulfil the ILAR criteria for sJIA. This study was undertaken to determine whether the Yamaguchi criteria (for adult onset Still’s di...

    Authors: Sharath Kumar, Divya Shree Kunhiraman and Lalitha Rajam
    Citation: Pediatric Rheumatology 2012 10:40
    Content type: Research Published on:

  29. The epidemiology of juvenile idiopathic arthritis (JIA) is variable worldwide. In particular, a wide disparity exists in the prevalence of the diverse disease subtypes across different geographic areas. The th...

    Authors: Alessandro Consolaro, Nicolino Ruperto, Giovanni Filocamo, Stefano Lanni, Giulia Bracciolini, Marco Garrone, Silvia Scala, Luca Villa, Giuseppe Silvestri, Daniela Tani, Alessandra Zolesi, Alberto Martini and Angelo Ravelli
    Citation: Pediatric Rheumatology 2012 10:39
    Content type: Review Published on:

  31. The aetiology of juvenile idiopathic arthritis (JIA) is largely unknown. We have established a JIA biobank in Melbourne, Australia called CLARITY – C hiL dhood A rthritis R isk factor I dentification sT udY, with...

    Authors: Justine A Ellis, Anne-Louise Ponsonby, Angela Pezic, Raul A Chavez, Roger C Allen, Jonathan D Akikusa and Jane E Munro
    Citation: Pediatric Rheumatology 2012 10:37
    Content type: Research Published on:

  32. To increase understanding of the healthcare transition (HCT) process for young people living with Juvenile Idopathic Arthritis (JIA) by examining: 1) the extent to which youth report discussing HCT topics with...

    Authors: Courtney Kellerman Wells, Barbara J McMorris, Keith J Horvath, Ann W Garwick and Peter B Scal
    Citation: Pediatric Rheumatology 2012 10:36
    Content type: Research Published on:

  34. We tested the hypothesis that the course and outcome of juvenile dermatomyositis (JDM) in children seen at one center with the JDM disease onset at or below three years of age is different from that in the chi...

    Authors: Anjali Patwardhan, Robert Rennebohm, Igor Dvorchik and Charles H Spencer
    Citation: Pediatric Rheumatology 2012 10:34
    Content type: Research Published on:

  35. Juvenile Idiopathic Arthritis (JIA) affects children and adolescents with both short-term and long-term disability. These children also report lower health-related quality of life (HRQOL) compared to their hea...

    Authors: Veronica Lundberg, Viveca Lindh, Catharina Eriksson, Solveig Petersen and Eva Eurenius
    Citation: Pediatric Rheumatology 2012 10:33
    Content type: Research Published on:

    The Correction to this article has been published in Pediatric Rheumatology 2018 16:53

  36. We report a now 6-year-old African-American male with both Alagille syndrome and pediatric sarcoidosis. With a prior JAG1 mutation positive diagnosis of Alagille syndrome, he presented to the hospital with a suba...

    Authors: Melissa Mannion, Mem Zolak, David R Kelly, Timothy Beukelman and Randy Q Cron
    Citation: Pediatric Rheumatology 2012 10:32
    Content type: Case Report Published on:

  37. The management of background corticosteroid therapy in rheumatology clinical trials poses a major challenge. We describe the consensus methodology used to design an algorithm to standardize changes in corticos...

    Authors: Norman T Ilowite, Christy I Sandborg, Brian M Feldman, Alexi Grom, Laura E Schanberg, Edward H Giannini, Carol A Wallace, Rayfel Schneider, Kathleen Kenney, Beth Gottlieb, Philip J Hashkes, Lisa Imundo, Yukiko Kimura, Bianca Lang, Michael Miller, Diana Milojevic…
    Citation: Pediatric Rheumatology 2012 10:31
    Content type: Research Published on:

  38. Tocilizumab (TCZ) is the first FDA- approved treatment for systemic juvenile idiopathic arthritis (sJIA). We report 3 cases of cytopenias in children with sJIA treated with TCZ. Two of the children who develop...

    Authors: Elizabeth A Kessler, Sheetal S Vora and James W Verbsky
    Citation: Pediatric Rheumatology 2012 10:30
    Content type: Case Report Published on:

  39. Anti-citrullinated protein/peptide antibodies (ACPA), have high specificity for rheumatoid arthritis (RA). Some children with juvenile idiopathic arthritis (JIA), phenotypically resemble RA and test positive f...

    Authors: Anne E Tebo, Troy Jaskowski, K Wayne Davis, April Whiting, Bronte Clifford, Andrew Zeft, Bernadette McNally, Harry R Hill, John Bohnsack and Sampath Prahalad
    Citation: Pediatric Rheumatology 2012 10:29
    Content type: Research Published on:

  40. The present report describes the severe evolution of Kawasaki disease in a three-month-old infant. The ailment was initially atypical in its presentation, with the patient exhibiting only persistent fever in a...

    Authors: Cristina Medeiros Ribeiro de Magalhães, Natália Ribeiro de Magalhães Alves, Adriana Valença de Melo, Clodoaldo Abreu da Silveira Junior, Yanna Karla de Medeiros Nόbrega, Lenora Gandolfi and Riccardo Pratesi
    Citation: Pediatric Rheumatology 2012 10:28
    Content type: Case Report Published on:

  41. As patients with juvenile idiopathic arthritis (JIA) progress into adulthood, long-term outcome is determined by disease activity, physical and psychosocial development. Decreased aerobic capacity may play a c...

    Authors: Philomien A van Pelt, Tim Takken, Marco van Brussel, Inge de Witte, Aike A Kruize and Nico M Wulffraat
    Citation: Pediatric Rheumatology 2012 10:27
    Content type: Research Published on:

  42. The temporomandibular (TMJ) is frequently involved in juvenile idiopathic arthritis (JIA), however little is known about management of this joint once a patient transitions from pediatric to adult care and abo...

    Authors: Sarah Ringold, Nikolay Tzaribachev and Randy Q Cron
    Citation: Pediatric Rheumatology 2012 10:26
    Content type: Short Report Published on:

  43. As patients with juvenile idiopathic arthritis (JIA) progress into adulthood, long-term outcome is determined by disease activity, physical and psychosocial development. Decreased aerobic capacity may play a c...

    Authors: Philomine A van Pelt, Tim Takken, Marco van Brussel, Mirjam de Witte, Aike A Kruize and Nico M Wulffraat
    Citation: Pediatric Rheumatology 2012 10:25
    Content type: Research Published on:

  44. Paediatric systemic lupus erythematosus (pSLE) exhibits an aggressive clinical phenotype with severe complications and overall poor prognosis. The aim of this study was to analyse differential expression of lo...

    Authors: Anita Rana, Ranjana W Minz, Ritu Aggarwal, Sadhna Sharma, Neelam Pasricha, Shashi Anand and Surjit Singh
    Citation: Pediatric Rheumatology 2012 10:24
    Content type: Research Published on:

  45. In juvenile idiopathic arthritis (JIA), the trend towards early therapeutic intervention and the development of new highly effective treatments have increased the need for sensitive and specific imaging. Numer...

    Authors: Louise Laurell, Michel Court-Payen, Susan Nielsen, Marek Zak, Mikael Boesen and Anders Fasth
    Citation: Pediatric Rheumatology 2012 10:23
    Content type: Research Published on:

  46. A high prevalence of autoimmune disease (AD) has been documented in relatives of adult patients with systemic lupus erythematosus (SLE). However, data on familial inheritance patterns in pediatric SLE patients...

    Authors: Heather M Walters, Nancy Pan, Lakshmi N Moorthy, Mary J Ward, Margaret G Peterson and Thomas J Lehman
    Citation: Pediatric Rheumatology 2012 10:22
    Content type: Short Report Published on:

  48. MRI has become the mainstay of diagnostic imaging in paediatric rheumatology for lesion detection, differential diagnosis and therapy surveillance. MR imaging of synovitis, in particular, is indispensable for ...

    Authors: Henning Neubauer, Laura Evangelista, Henner Morbach, Hermann Girschick, Martina Prelog, Herbert Köstler, Dietbert Hahn and Meinrad Beer
    Citation: Pediatric Rheumatology 2012 10:20
    Content type: Research Published on:

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