Prior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable

Our intent was to identify differences between the transcriptome of fibroblast-like synoviocytes (FLS) in oligoarticular juvenile idiopathic arthritis (JIA) before extension when compared to persistent subtype...

Authors: AnneMarie C. Brescia, Megan M. Simonds, Suzanne M. McCahan, Kathleen E. Sullivan and Carlos D. Rose

Patient characteristics associated with response to NSAID monotherapy in children with systemic juvenile idiopathic arthritis

Systemic juvenile idiopathic arthritis (sJIA) is an auto-inflammatory disease characterized by fever, arthritis, and ≥1 of rash, generalized lymphadenopathy, hepato/splenomegaly, and serositis. Non-steroidal a...

Authors: Anjali Sura, Christopher Failing, Julie Sturza, Jasmine Stannard and Meredith Riebschleger

Cone beam computed tomography for the assessment of linear scleroderma of the face

To date, standardized methods for assessing the disease progression of linear scleroderma of the face (LSF) are lacking.

Authors: C. Di Giovanni, S. Puggina, A. Meneghel, F. Vittadello, G. Martini and F. Zulian

Dealing with Chronic Non-Bacterial Osteomyelitis: a practical approach

Chronic Non-Bacterial Osteomyelitis (CNO) is an inflammatory disorder that primarily affects children. Although underestimated, its incidence is rare. For these reasons, no diagnostic and no therapeutic guidel...

Authors: Andrea Taddio, Giovanna Ferrara, Antonella Insalaco, Manuela Pardeo, Massimo Gregori, Martina Finetti, Serena Pastore, Alberto Tommasini, Alessandro Ventura and Marco Gattorno

“Next generation sequencing identifies mutations in GNPTG gene as a cause of familial form of scleroderma-like disease”

Authors: Afolake T. Arowolo, Henry A. Adeola and Nonhlanhla P. Khumalo

Mental health care for youth with rheumatologic diseases – bridging the gap

Youth with rheumatologic diseases have a high prevalence of comorbid mental health disorders. Individuals with comorbid mental health disorders are at increased risk for adverse outcomes related to mental heal...

Authors: Alaina M. Davis, Tamar B. Rubinstein, Martha Rodriguez and Andrea M. Knight

Pharmacokinetic and safety profile of tofacitinib in children with polyarticular course juvenile idiopathic arthritis: results of a phase 1, open-label, multicenter study

Juvenile idiopathic arthritis (JIA) is the most common pediatric rheumatic disease and a leading cause of childhood disability. The objective of this study was to characterize the PK, safety, and taste accepta...

Authors: Nicolino Ruperto, Hermine I. Brunner, Zbigniew Zuber, Nikolay Tzaribachev, Daniel J. Kingsbury, Ivan Foeldvari, Gerd Horneff, Elzbieta Smolewska, Richard K. Vehe, Anasuya Hazra, Rong Wang, Charles A. Mebus, Christine Alvey, Manisha Lamba, Sriram Krishnaswami, Thomas C. Stock…

A national cohort study on pediatric Behçet’s disease: cross-sectional data from an Italian registry

Behçet’s disease is a rare multi-systemic inflammatory disease with unknown etiology which involves principally oral and genital mucosa, skin and eyes. Average age at onset of the disease is about 25-30 years,...

Authors: Romina Gallizzi, Caterina Pidone, Luca Cantarini, Martina Finetti, Marco Cattalini, Giovanni Filocamo, Antonella Insalaco, Donato Rigante, Rita Consolini, Maria Cristina Maggio, Adele Civino, Silvana Martino, Alma Nunzia Olivieri, Giovanna Fabio, Serena Pastore, Angela Mauro…

Correction to: P92 chronic arthritis as the only manifestation of FMF in Armenian children

Familial Mediterranean Fever (FMF) is the most common inherited auto inflammatory disease, characterized by recurrent, self–limited attacks of fever and aseptic polyserositis.FMF is widespread in Armenia and t...

Authors: Gayane Khloyan, Gayane Amaryan and Rotraud Saurenmann

Anatomy of the sacroiliac joints in children and adolescents by computed tomography

Diagnosing sacroiliitis by magnetic resonance imaging (MRI) in children/adolescents can be difficult due to the growth-related changes. This study analyzed the normal osseous anatomy of the sacroiliac joints (...

Authors: Anna Zejden and Anne Grethe Jurik

Functional resonance magnetic imaging (fMRI) in adolescents with idiopathic musculoskeletal pain: a paradigm of experimental pain

Studies on functional magnetic resonance imaging (fMRI) have shown that adults with musculoskeletal pain syndromes tolerate smaller amount of pressure (pain) as well as differences in brain activation patterns...

Authors: Juliana Molina, Edson Amaro Jr, Liana Guerra Sanches da Rocha, Liliana Jorge, Flavia Heloisa Santos and Claudio A. Len

Patients with juvenile idiopathic arthritis in clinical remission with positive power Doppler signal in joint ultrasonography have an increased rate of clinical flare: a prospective study

Ultrasonography (US) studies carried out on joints of juvenile idiopathic arthritis (JIA) patients in clinical remission demonstrate the presence of subclinical synovitis. The significance of subclinical synov...

Authors: Vanessa Bugni Miotto e Silva, Sônia de Aguiar Vilela Mitraud, Rita Nely Vilar Furtado, Jamil Natour, Claudio Arnaldo Len and Maria Teresa de Sande e Lemos Ramos Ascensão Terreri

Risk of tuberculosis among Alabama children and adolescents treated with tumor necrosis factor inhibitors: a retrospective study

Tumor Necrosis Factor inhibitors (TNFi) have dramatically improved the outlook for patients with inflammatory arthritides and bowel disease (IBD), but are associated with increased infection risks, including t...

Authors: Matthew L. Stoll, James Aaron Grubbs, Timothy Beukelman, Melissa L. Mannion, Traci W. Jester, Randy Q. Cron and Marilyn J. Crain

Protocols on classification, monitoring and therapy in children’s rheumatology (PRO-KIND): results of the working group Polyarticular juvenile idiopathic arthritis

Several effective pharmacologic treatment options for polyarticual juvenile idiopathic arthritis (JIA) have emerged but initial treatment is heterogeneous in Germany. Therefore, the German Society of Pediatric...

Authors: Gerd Horneff, Ariane Klein, Gerd Ganser, Michaela Sailer-Höck, Annette Günther, Ivan Foeldvari and Frank Weller-Heinemann

Effective induction therapy for anti-SRP associated myositis in childhood: A small case series and review of the literature

Anti-Signal Recognition Particle associated myopathy is a clinically and histopathologically distinct subgroup of Juvenile Idiopathic Inflammatory Myositis, which is under-recognised in children and fails to r...

Authors: E. L. Binns, E. Moraitis, S. Maillard, S. Tansley, N. McHugh, T. S. Jacques, L. R. Wedderburn, C. Pilkington, S. A. Yasin and K. Nistala

H syndrome: 5 new cases from the United States with novel features and responses to therapy

H Syndrome is an autosomal recessive disorder characterized by cutaneous hyperpigmentation, hypertrichosis, and induration with numerous systemic manifestations. The syndrome is caused by mutations in SLC29A3, a ...

Authors: Jessica L. Bloom, Clara Lin, Lisa Imundo, Stephen Guthery, Shelly Stepenaskie, Csaba Galambos, Amy Lowichik and John F. Bohnsack

Short term effectiveness and experiences of a peer guided web-based self-management intervention for young adults with juvenile idiopathic arthritis

A web-based self-management intervention guided by peer-trainers was developed to support young adults’ self-management in coping with Juvenile Idiopathic Arthritis (JIA). To investigate its effectiveness, a r...

Authors: Judy Ammerlaan, Harmieke van Os-Medendorp, Nienke de Boer-Nijhof, Lieske Scholtus, Aike A. Kruize, Philomine van Pelt, Berent Prakken and Hans Bijlsma

Effects of age and gender on reference levels of biomarkers comprising the pediatric Renal Activity Index for Lupus Nephritis (p-RAIL)

Systemic Lupus Erythematosus (SLE) is a multisystem autoimmune disease that disproportionately effects women and children of minorities. Renal involvement (lupus nephritis, or LN) occurs in up to 80% of childr...

Authors: Michael R. Bennett, Qing Ma, Jun Ying, Prasad Devarajan and Hermine Brunner

Readout-segmented multi-shot diffusion-weighted MRI of the knee joint in patients with juvenile idiopathic arthritis

Diffusion-weighted MRI has been proposed as a new technique for imaging synovitis without intravenous contrast application. We investigated diagnostic utility of multi-shot readout-segmented diffusion-weighted...

Authors: Alexander Sauer, Mengxia Li, Annette Holl-Wieden, Thomas Pabst and Henning Neubauer

Next Generation Sequencing identifies mutations in GNPTG gene as a cause of familial form of scleroderma-like disease

Scleroderma is a multisystem disease, characterized by fibrosis of skin and internal organs, immune dysregulation, and vasculopathy. The etiology of the disease remains unknown, but it is likely multifactorial...

Authors: Abdelali Zrhidri, Saadia Amasdl, Jaber Lyahyai, Hanane Elouardi, Bouchra Chkirate, Laure Raymond, Grégory Egéa, Mohamed Taoudi, Said El Mouatassim and Abdelaziz Sefiani

Assessment, classification and treatment of calcinosis as a complication of juvenile dermatomyositis: a survey of pediatric rheumatologists by the childhood arthritis and rheumatology research alliance (CARRA)

There is no standardized approach to the management of JDM-associated calcinosis and its phenotypes. Current knowledge of treatment outcomes is confined to small series and case reports. We describe physician ...

Authors: A. B. Orandi, K. W. Baszis, V. R. Dharnidharka, A. M. Huber and M. F. Hoeltzel

Assessment of transition readiness in adolescents and young adults with chronic health conditions

Transition from pediatric to adult health care is a vulnerable period for adolescents and young adults. Challenges include paucity of validated measures to assess patients’ transition readiness. We evaluated t...

Authors: Paul T. Jensen, Gabrielle V. Paul, Stephanie LaCount, Juan Peng, Charles H. Spencer, Gloria C. Higgins, Brendan Boyle, Manmohan Kamboj, Christopher Smallwood and Stacy P. Ardoin

Comics as an educational tool for children with juvenile idiopathic arthritis

This study examined whether the comic book Neta and the Medikidz Explain JIA would improve disease-related knowledge and treatment adherence among patients with juvenile idiopathic arthritis (JIA).

Authors: Amir Mendelson, Noa Rabinowicz, Yonit Reis, Gil Amarilyo, Liora Harel, Philip J Hashkes and Yosef Uziel

Proceedings of the 24^th Paediatric Rheumatology European Society Congress: Part one

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Proceedings of the 24^th Paediatric Rheumatology European Society Congress: Part two

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