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  1. Case report

    Simultaneous development of Kawasaki disease following acute human adenovirus infection in monozygotic twins: A case report

    The etiology of Kawasaki disease (KD) remains unknown. However, many studies have suggested that specific genetic factors and/or some infectious agents underlie the onset of KD. Previous studies have suggested...

    Sayaka Fukuda, Shuichi Ito, Maya Fujiwara, Jun Abe, Nozomu Hanaoka, Tsuguto Fujimoto and Hiroshi Katsumori

    Pediatric Rheumatology 2017 15:39

    Published on: 16 May 2017

  2. Research article

    Clinical and MRI outcome of cervical spine lesions in children with juvenile idiopathic arthritis treated with anti-TNFα drugs early in disease course

    The purpose of the study was to evaluate the clinical and magnetic resonance imaging (MRI) outcome of cervical spine arthritis in children with juvenile idiopathic arthritis (JIA), who received anti-TNFα early...

    Damjana Ključevšek, Nina Emeršič, Nataša Toplak and Tadej Avčin

    Pediatric Rheumatology 2017 15:38

    Published on: 15 May 2017

  3. Review

    When a patient suspected with juvenile idiopathic arthritis turns out to be diagnosed with an infectious disease – a review of Lyme arthritis in children

    The Lyme arthritis is a common manifestation of infection with Borrelia burgdorferi spirochete. Despite its infectious background, the inflammation clinically and histopatologically resembles juvenile idiopathic ...

    Krzysztof Orczyk, Joanna Świdrowska-Jaros and Elżbieta Smolewska

    Pediatric Rheumatology 2017 15:35

    Published on: 8 May 2017

  4. Short report

    Arterial stiffness by oscillometric device and telomere lenght in juvenile idiopathic artrhitis with no cardiovascular risk factors: a cross-sectional study

    Advances in juvenile idiopathic arthritis (JIA) treatment is promoting free disease survival. Cardiovascular disease (CVD) may emerge as an important cause of morbidity and mortality. Pulse wave velocity (PWV)...

    Maria Mercedes Picarelli, Luiz Cláudio Danzmann, Lucas Kich Grun, Nevton Teixeira Rosa Júnior, Patrícia Lavandovsky, Fátima Theresinha Costa Rodrigues Guma, Renato T. Stein, Florência Barbé-Tuana and Marcus Herbert Jones

    Pediatric Rheumatology 2017 15:34

    Published on: 4 May 2017

  5. Review

    Intestinal Behçet and Crohn’s disease: two sides of the same coin

    Behçet’s disease (BD) and Crohn’s disease (CD) are chronic immune-mediated, inflammatory disorders affecting many different systems (joints, skin, eyes, gastrointestinal and biliary tracts). Both disorders hav...

    Simona Valenti, Romina Gallizzi, Dominique De Vivo and Claudio Romano

    Pediatric Rheumatology 2017 15:33

    Published on: 20 April 2017

  6. Research article

    Observational study of Interleukin-21 (IL-21) does not distinguish Kawasaki disease from other causes of fever in children

    Kawasaki disease (KD) is a febrile childhood vasculitis of unknown etiology. The diagnosis is highly concerning as over a quarter of children who fail to receive timely treatment with intravenous immunoglobuli...

    Rachel Engelberg, Meghan Martin, Brian H. Wrotniak and Mark Daniel Hicar

    Pediatric Rheumatology 2017 15:32

    Published on: 20 April 2017

  7. Research article

    A survey of national and multi-national registries and cohort studies in juvenile idiopathic arthritis: challenges and opportunities

    To characterize the existing national and multi-national registries and cohort studies in juvenile idiopathic arthritis (JIA) and identify differences as well as areas of potential future collaboration.

    Timothy Beukelman, Janneke Anink, Lillemor Berntson, Ciaran Duffy, Justine A. Ellis, Mia Glerup, Jaime Guzman, Gerd Horneff, Lianne Kearsley-Fleet, Ariane Klein, Jens Klotsche, Bo Magnusson, Kirsten Minden, Jane E. Munro, Martina Niewerth, Ellen Nordal…

    Pediatric Rheumatology 2017 15:31

    Published on: 19 April 2017

  8. Research article

    The new Childhood Arthritis and Rheumatology Research Alliance (CARRA) registry: design, rationale, and characteristics of patients enrolled in the first 12 months

    Herein we describe the history, design, and rationale of the new Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry and present the characteristics of patients with juvenile idiopathic art...

    Timothy Beukelman, Yukiko Kimura, Norman T. Ilowite, Kelly Mieszkalski, Marc D. Natter, Grendel Burrell, Brian Best, Jason Jones and Laura E. Schanberg

    Pediatric Rheumatology 2017 15:30

    Published on: 17 April 2017

  9. Review

    Lung involvement in childhood onset granulomatosis with polyangiitis

    Granulomatosis with polyangiitis is an ANCA-associated systemic vasculitis with a low incidence in the pediatric population. Lung involvement is a common manifestation in children affected by granulomatosis wi...

    Giovanni Filocamo, Sofia Torreggiani, Carlo Agostoni and Susanna Esposito

    Pediatric Rheumatology 2017 15:28

    Published on: 14 April 2017

  10. Research article

    Health-related quality of life among Swedish children with Juvenile Idiopathic Arthritis: parent–child discrepancies, gender differences and comparison with a European cohort

    This study investigates gender differences in self-reports and between parent and child reports in Health-related Quality of Life (HRQOL), measured with disease-specific and generic instruments for chronic dis...

    Veronica Lundberg and Catharina Eriksson

    Pediatric Rheumatology 2017 15:26

    Published on: 12 April 2017

  11. Research article

    Muscle MRI at the time of questionable disease flares in Juvenile Dermatomyositis (JDM)

    The course of JDM has improved substantially over the last 70 years with early and aggressive treatments. Yet it remains difficult to detect disease flares as symptoms may be mild; signs of rash and muscle wea...

    Rabheh Abdul-Aziz, Chack-Yung Yu, Brent Adler, Sharon Bout-Tabaku, Katherine E. Lintner, Melissa Moore-Clingenpeel and Charles H. Spencer

    Pediatric Rheumatology 2017 15:25

    Published on: 12 April 2017

  12. Regular article

    Pilot study comparing the Childhood Arthritis & Rheumatology Research Alliance (CARRA) systemic Juvenile Idiopathic Arthritis Consensus Treatment Plans

    To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment plans (CTPs) for systemic Juvenile Idiopathic Arthr...

    Yukiko Kimura, Sriharsha Grevich, Timothy Beukelman, Esi Morgan, Peter A. Nigrovic, Kelly Mieszkalski, T Brent Graham, Maria Ibarra, Norman Ilowite, Marisa Klein-Gitelman, Karen Onel, Sampath Prahalad, Marilynn Punaro, Sarah Ringold, Dana Toib, Heather Van Mater…

    Pediatric Rheumatology 2017 15:23

    Published on: 11 April 2017

  13. Research article

    ASAS definition for sacroiliitis on MRI in SpA: applicable to children?

    The Assessment of Spondyloarthritis International Society (ASAS) definition for a ‘positive’ Magnetic Resonance Imaging (MRI) for sacroiliitis is well studied and validated in adults, but studies about the val...

    Nele Herregods, Joke Dehoorne, Filip Van den Bosch, Jacob Lester Jaremko, Joke Van Vlaenderen, Rik Joos, Xenofon Baraliakos, Gaëlle Varkas, Koenraad Verstraete, Dirk Elewaut and Lennart Jans

    Pediatric Rheumatology 2017 15:24

    Published on: 11 April 2017

  14. Research article

    Radiographic damage in hands and wrists of patients with juvenile idiopathic arthritis after 29 years of disease duration

    There are few studies on radiographic outcome after long-term disease duration in juvenile idiopathic arthritis (JIA). We wanted to evaluate 29-year radiographic outcome in hands/wrists and predictors of damag...

    Anne M. Selvaag, Eva Kirkhus, Lena Törnqvist, Vibke Lilleby, Hanne A. Aulie and Berit Flatø

    Pediatric Rheumatology 2017 15:20

    Published on: 11 April 2017

  15. Research article

    Ultrasound-guided steroid tendon sheath injections in juvenile idiopathic arthritis: a 10-year single-center retrospective study

    The aims of this study were to: (a) Identify tendon sheaths most commonly treated with steroid injections in a pediatric patient population with Juvenile Idiopathic Arthritis (JIA); (b) Describe technical aspe...

    Shannon E. Peters, Ronald M. Laxer, Bairbre L. Connolly and Dimitri A. Parra

    Pediatric Rheumatology 2017 15:22

    Published on: 11 April 2017

  16. Regular article

    BK viruria and viremia in children with systemic lupus erythematosus

    BK virus (BKV) is a ubiquitous polyoma virus that lies dormant in the genitourinary tract once acquired in early childhood. In states of cellular immunodeficiency, the virus can reactivate to cause hemorrhagic...

    Nirupama Gupta, Cuong Q. Nguyen, Renee F. Modica, Melissa E. Elder and Eduardo H. Garin

    Pediatric Rheumatology 2017 15:21

    Published on: 11 April 2017

  17. Case report

    Munchausen by proxy syndrome mimicking systemic autoinflammatory disease: case report and review of the literature

    Systemic autoinflammatory diseases (SAIDs) represent a growing number of monogenic, polygenic or multifactorial disorders that are often difficult to diagnose.

    Helmut Wittkowski, Claas Hinze, Sigrid Häfner-Harms, Vinzenz Oji, Katja Masjosthusmann, Martina Monninger, Ulrike Grenzebach and Dirk Foell

    Pediatric Rheumatology 2017 15:19

    Published on: 5 April 2017

  18. Review

    Methods for analyzing observational longitudinal prognosis studies for rheumatic diseases: a review & worked example using a clinic-based cohort of juvenile dermatomyositis patients

    Most outcome studies of rheumatic diseases report outcomes ascertained on a single occasion. While single assessments are sufficient for terminal or irreversible outcomes, they may not be sufficiently informat...

    Lily Siok Hoon Lim, Eleanor Pullenayegum, Rahim Moineddin, Dafna D Gladman, Earl D Silverman and Brian M Feldman

    Pediatric Rheumatology 2017 15:18

    Published on: 29 March 2017

  19. Research article

    Missed opportunities for timely diagnosis of pediatric lupus in South Africa: a qualitative study

    Systemic Lupus Erythematosus (SLE) is a serious multisystem autoimmune disease, which is more aggressive in children and people of African descent. In South Africa, pediatric SLE (pSLE) patients are at high ri...

    Laura B. Lewandowski, Melissa H. Watt, Laura E. Schanberg, Nathan M. Thielman and Christiaan Scott

    Pediatric Rheumatology 2017 15:14

    Published on: 23 February 2017

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