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  1. It has been reported that the complete heart block (CHB) in neonatal lupus (NL) cannot be reversed. This study reported a case of NL-CHB that was reversed by transcutaneous pacing and repeated plasmapheresis.

    Authors: Yanfei Liu, Wanwei Li, Kun Zhou and Zhangxue Hu
    Citation: Pediatric Rheumatology 2023 21:135
  2. Juvenile Idiopathic Arthritis (JIA) is the most common form of childhood inflammatory arthritis. The disease burden of JIA is substantial as patients require specialized medical practitioners for diagnosis and...

    Authors: Niloofar Gheshlaghi, Megan Thomas, Natasha Trehan, Mark Harrison and Mary A. De Vera
    Citation: Pediatric Rheumatology 2023 21:134
  3. Pediatric musculoskeletal disorders account for 10% of first-line consultations in Tunisia. Referral delay and deficiencies in musculoskeletal screening raise a challenge to the early diagnosis and management ...

    Authors: Lassoued Ferjani Hanene, Narjess Amdouni, Rabhi Emna, Sahli Hela, Ben Abdelgheni Kaouther, Ben Nessib Dorra, Kaffel Dhia, Maatallah Kaouther and Hamdi Wafa
    Citation: Pediatric Rheumatology 2023 21:133
  4. Gain-of-function mutations in STING1 (also known as TMEM173) which result in constitutive activation of STING, have been reported to cause STING-associated vasculopathy with onset in infancy (SAVI). Although a wi...

    Authors: Jianqiang Wu, Qing Zhou, Hua Zhou and Meiping Lu
    Citation: Pediatric Rheumatology 2023 21:131
  5. Systemic lupus erythematosus is an autoimmune disease that involves multiple organ systems. One of its major complications, lupus nephritis (LN), is associated with a high mortality rate, and children-onset LN...

    Authors: Shi-jie Li, Dan-dan Ruan, Wei-zhen Wu, Min Wu, Qiu-yan Wu, Han-lu Wang, Yuan-yuan Ji, Yan-ping Zhang, Xin-fu Lin, Zhu-ting Fang, Li-sheng Liao, Jie-wei Luo, Mei-zhu Gao and Jia-bin Wu
    Citation: Pediatric Rheumatology 2023 21:130
  6. The linkage between prolactin (PRL) and systemic lupus erythematosus (SLE) is still vague. Determination of serum levels of prolactin to reveal its role in patients with SLE is the aim of the study.

    Authors: Hend Mehawed Soliman, Balsam Sherif Fahmy, Moataz Gamal Ali and Eman Shafik Shafie
    Citation: Pediatric Rheumatology 2023 21:128
  7. Insights into the immunological role of the gastrointestinal tract in autoimmune conditions have led to the investigation of diet as a potential adjunctive treatment option for juvenile idiopathic arthritis (J...

    Authors: Naima Hagström, Elin Lövestam, Afsaneh Koochek and Lillemor Berntson
    Citation: Pediatric Rheumatology 2023 21:127
  8. Connective tissue nevi (CTN) are congenital hamartomas caused by excessive proliferation of dermis components. In children, CTN can mimic juvenile localized scleroderma (JLS), an immune mediated skin disorder ...

    Authors: F. Tirelli, C. Giraudo, M. Soliani, F. Calabrese, G. Martini, P. Gisondi, A. Meneghel and Francesco Zulian
    Citation: Pediatric Rheumatology 2023 21:125
  9. Monogenic autoinflammatory diseases (AIDs) are rare inflammatory diseases caused by genetic variants. The pathogenesis is complex and treatment options are limited. This study aimed to describe the safety and ...

    Authors: Caihui Zhang, Zhongxun Yu, Sihao Gao, Mingsheng Ma, Lijuan Gou, Changyan Wang, Lin Wang, Ji Li, Linqing Zhong, Yu Zhou, Wei Wang and Hongmei Song
    Citation: Pediatric Rheumatology 2023 21:124
  10. Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that is associated with multiple organ involvement and leads to significant morbidity and mortality. One of the important environmental facto...

    Authors: Porntipa Suebsarakam and Dara Mairiang
    Citation: Pediatric Rheumatology 2023 21:123
  11. Hypermobile Ehlers-Danlos syndrome (hEDS) is characterized by joint and skin laxity, and often accompanied by chronic pain, dysautonomia, increased distress and, functional limitations. The journey to accurate...

    Authors: Estée C.H. Feldman, Kendra J. Homan, Sara E. Williams, Tracy V. Ting, Kenneth R. Goldschneider and Susmita Kashikar-Zuck
    Citation: Pediatric Rheumatology 2023 21:121
  12. Pediatric rheumatology faces a looming supply-demand crisis. While strategies have been proposed to address the supply shortfall, investigation into the increased demand for pediatric rheumatic care has been l...

    Authors: Daniel D Reiff, John M Bridges, Eileen C Rife, Victoria L Gennaro, Linda McAllister, Annelle Reed, Carolyn Smith, Bethany Walker, Peter Weiser, Emily A Smitherman, Matthew L Stoll, Melissa L Mannion and Randy Q Cron
    Citation: Pediatric Rheumatology 2023 21:120
  13. Sjögren’s syndrome (SS) is a rare disease with unclear diagnostic criteria among the children and adolescents. The purpose of this study is to describe the clinical features of pediatric Sjögren’s syndrome and...

    Authors: Ling Hou, Ningning Wang, Chengguang Zhao, Xiuli Wang and Yue Du
    Citation: Pediatric Rheumatology 2023 21:119
  14. We lack a reliable indicator of disease activity in Juvenile Dermatomyositis (JDM), a rare disease. The goal of this study is to identify the association of nailfold capillary End Row Loop (ERL) loss with dise...

    Authors: Lauren M. Pachman, Gabrielle Morgan, Marisa S. Klein-Gitelman, Najah Ahsan and Amer Khojah
    Citation: Pediatric Rheumatology 2023 21:118
  15. Aicardi-Goutières syndrome (AGS) is a rare hereditary early-onset encephalopathy characterized by upregulation of the type I interferon pathway, poorly responsive to conventional immunosuppression.

    Authors: Wei Wang, Wei Wang, Siming Peng, Sihao Gao, Meiying Quan, Lijuan Gou, Changyan Wang, Zhixing Sun, Zhuo Li, Dongmei Lian and Hongmei Song
    Citation: Pediatric Rheumatology 2023 21:117
  16. Physiotherapy appears as a promising therapy option for patients with Juvenile Idiopathic Arthritis (JIA) [1, 2], but the effects of physiotherapy and jaw exercises on JIA-related orofacial symptoms remain unknow...

    Authors: Stratos Vassis, Cory M. Resnick, Mette Nørgaard, Kathleen M. Strawn, Helle Grove, Beatrice Noeldeke, Troels Herlin, Thomas Klit Pedersen and Peter Bangsgaard Stoustrup
    Citation: Pediatric Rheumatology 2023 21:116
  17. Macrophage activation syndrome (MAS) is a severe, potentially fatal complication of rheumatic diseases, predominantly in systemic juvenile idiopathic arthritis (SJIA), and is considered as an autoinflammatory ...

    Authors: Meiping Lu, Liping Teng, Yiping Xu and Xuefeng Xu
    Citation: Pediatric Rheumatology 2023 21:115
  18. The epidemiology of Juvenile Dermatomyositis (JDM) in non-Caucasian population is poorly described. We performed a study of patients followed up in the French West Indies for JDM. We aimed to describe clinical...

    Authors: Arthur Felix, Frederique Delion, Fabienne Louis-Sidney, Lindsay Osei, Aurélie Armougon, Remi Bellance, Moustapha Dramé, Christophe Deligny, Benoit Suzon and Yves Hatchuel
    Citation: Pediatric Rheumatology 2023 21:113
  19. Anakinra is a recombinant interleukin-1 (IL-1) receptor antagonist used in systemic juvenile idiopathic arthritis (sJIA), refractory Kawasaki disease (KD) and cryopyrin-associated autoinflammatory syndrome (CA...

    Authors: Frederico Rajão Martins, André Costa Azevedo, Sara Ganhão, Francisca Aguiar, Mariana Rodrigues and Iva Brito
    Citation: Pediatric Rheumatology 2023 21:112
  20. This paper presents insight into the scale of mental health concerns for families who have a child or young person with a diagnosis of Juvenile Idiopathic Arthritis (JIA) living in any of the four nations of t...

    Authors: Polly Livermore, S. Ainsworth, R. Beesley, S. Douglas, E. Earle, D. Wilson, L. Woolley and J. Clinch
    Citation: Pediatric Rheumatology 2023 21:111
  21. The prevalence of Celiac Disease (CD) in Juvenile Idiopathic Arthritis (JIA) has been reported to be 0.1–7% in various small studies. As a result of the limited number of research and their inconclusive result...

    Authors: Angela Taneja Kohli, Aimee O. Hersh, Lori Ponder, Lai Hin Kimi Chan, Kelly A. Rouster-Stevens, Anne E. Tebo, Subra Kugathasan, Stephen L. Guthery, John F. Bohnsack and Sampath Prahalad
    Citation: Pediatric Rheumatology 2023 21:110
  22. Pediatric uveitis is a severe inflammatory ocular condition that can lead to sight-threatening complications and can negatively impact quality of life. The retinal microcirculation is often affected in interme...

    Authors: Carlyn V. Kouwenberg, Julia Spierings, Evianne L. de Groot, Joke H. de Boer and Viera Kalinina Ayuso
    Citation: Pediatric Rheumatology 2023 21:109
  23. The objective of this initiative was to develop a treat-to-target (T2T) approach for the management of patients with Familial Mediterranean Fever (FMF), including the definition of a complex treatment target, ...

    Authors: Lisa Ehlers, Elisabeth Rolfes, Mareike Lieber, Dominik Müller, Elke Lainka, Faekah Gohar, Günter Klaus, Hermann Girschick, Jana Hörstermann, Jasmin Kümmerle-Deschner, Jürgen Brunner, Katharina Palm-Beden, Klaus Tenbrock, Lusine von Wrangel, Maria Faßhauer, Norbert Blank…
    Citation: Pediatric Rheumatology 2023 21:108
  24. In juvenile idiopathic arthritis (JIA) clinical remission is unattainable in some patients despite modern biologic disease-modifying antirheumatic drugs (bDMARD) therapy and switching bDMARD is required. The b...

    Authors: Mia Lindegaard Pedersen, Amalie Neve-Græsbøll, Troels Herlin and Mia Glerup
    Citation: Pediatric Rheumatology 2023 21:107
  25. Macrophage activation syndrome (MAS) is a severe and life-threatening syndrome associated with autoimmune diseases. The coexistence of MAS and juvenile dermatomyositis (JDM) is not well reported. This report d...

    Authors: Yong Chang, Xueyan Shan and Yongpeng Ge
    Citation: Pediatric Rheumatology 2023 21:106
  26. Musculoskeletal ultrasound is a well accessible technique to assess disease activity in children with juvenile idiopathic arthritis. Knowledge of reference values of joint structures is indispensable to differ...

    Authors: Ruth Wittoek, Céline Decock, Nele Dewaele, Lara Arnold, Pieter Baeyens, Ignace De Schrijver, Lisa Pardaens, Ioannis Raftakis, Thomas Renson, Charline Rinkin, Alexander D. J. Thooft, Tine Vanhaverbeke and Caroline Verbist
    Citation: Pediatric Rheumatology 2023 21:105
  27. Juvenile dermatomyositis (jDM) is the most common idiopathic inflammatory myopathy of childhood. Amyopathic or hypomyopathic courses have been described.

    Authors: Timmy Strauss, Claudia Günther, Anja Schnabel, Christine Wolf, Gabriele Hahn, Min Ae Lee-Kirsch and Normi Brück
    Citation: Pediatric Rheumatology 2023 21:104
  28. Paediatric rheumatic diseases cause considerable disease burden to children and their families (Moorthy LN, Peterson MGE, Hassett AL, et al, Pediatric Rheumatology 8:20, 2010). Delayed diagnosis is a significa...

    Authors: Jacqueline E. Kawishe, Anthony Ngugi, Stanley Luchters, Helen Foster and Angela Migowa
    Citation: Pediatric Rheumatology 2023 21:103
  29. To identify baseline predictors of persisting pain in children with Juvenile Idiopathic Arthritis (JIA), relative to patients with JIA who had similar baseline levels of pain but in whom the pain did not persist.

    Authors: Tara McGrath, Jaime Guzman, Lori Tucker, Natalie J. Shiff, Maryna Yaskina, Susan Tupper and Dax G. Rumsey
    Citation: Pediatric Rheumatology 2023 21:102
  30. Sweet syndrome (SS), also known as acute febrile neutrophilic dermatosis, is an immunologic syndrome characterized by widespread neutrophilic infiltration. Histiocytoid Sweet syndrome (H-SS) is a histopatholog...

    Authors: Margaret Irwin, Veeraya K. Tanawattanacharoen, Amy Turner, Mary Beth F. Son, Rebecca C. Hale, Craig D. Platt, Juan Putra, Birgitta A.R. Schmidt and Mollie G. Wasserman
    Citation: Pediatric Rheumatology 2023 21:101
  31. Throughout the COVID-19 pandemic, there have been concerns regarding the risks of infection in patients with autoimmune disease. In this study, we investigated the impact of the pandemic on patients with juven...

    Authors: Dawn M. Wahezi, Dominique Jerome, Evin Rothschild, Belina Yi, Jeffrey Dvergsten, Stacey Tarvin, Susan Kim and Tamar Rubinstein
    Citation: Pediatric Rheumatology 2023 21:100
  32. Tocilizumab is a humanized monoclonal antibody that acts as an IL-6 receptor antagonist. Intravenous tocilizumab is considered an option for children with anti-TNF refractory juvenile idiopathic arthritis-asso...

    Authors: Francesca Burlo, Cristina Tumminelli, Serena Pastore, Gabriele Stocco, Debora Curci, Marianna Lucafò, Alberto Tommasini and Andrea Taddio
    Citation: Pediatric Rheumatology 2023 21:99
  33. Systemic juvenile idiopathic arthritis (systemic JIA) is a severe disease with both systemic and joint inflammation. This study aims to identify predictors of disease evolution within the systemic JIA populati...

    Authors: M. Wallimann, K. Bouayed, E. Cannizzaro, D. Kaiser, A. Belot, E. Merlin, S. Poignant, C. Wouters, F. Hofer, T. Saurenmann, A. Koryllou, R. Carlomagno, M. Mejbri, M. Hofer and K. Theodoropoulou
    Citation: Pediatric Rheumatology 2023 21:96
  34. Although the advent of new therapeutics for juvenile idiopathic arthritis (JIA) patients has considerably lessened the impact of the disease and reduced its sequelae, the outcomes of JIA remain important in th...

    Authors: Carine Savel, Aurélie Chausset, Pauline Berland, Candy Guiguet-Auclair, Laura Cabane, Bruno Fautrel, Philippe Gaudin, Pascale Guillot, Gilles Hayem, Delphine Lafarge, Etienne Merlin, Nadine Pezière, Christelle Sordet, Sonia Trope, Anne Tournadre, Sandrine Malochet…
    Citation: Pediatric Rheumatology 2023 21:95
  35. The aim of this long-term follow-up study was to compare the disease characteristics of HLA-B27 positive and negative patients with juvenile idiopathic arthritis (JIA).

    Authors: Suvi Oili Orvokki Peltoniemi, Mia Glerup, Pekka Lahdenne, Kari K Eklund and Kristiina Aalto
    Citation: Pediatric Rheumatology 2023 21:94
  36. Periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome is the most common periodic fever syndrome in children; by definition, episodes occur every 2 to 8 weeks. However, in a ...

    Authors: Mor Broide, Yoel Levinsky, Rotem Tal, Liora Harel, Shoval Shoham, Sabreen Abu Ahmad, Yonatan Butbul Aviel and Gil Amarilyo
    Citation: Pediatric Rheumatology 2023 21:93
  37. Fibrodysplasia ossificans progressive (FOP) is an ultra-rare genetic disorder that is caused by a mutation in the ACVR1 gene and provokes severe heterotopic ossification. Since flares of the disease are associate...

    Authors: Irina P. Nikishina, Svetlana V. Arsenyeva, Valeria G. Matkava, Alia N. Arefieva, Mariya I. Kaleda, Alexandr V. Smirnov, Leonid M. Blank and Mikhail M. Kostik
    Citation: Pediatric Rheumatology 2023 21:92
  38. The aim of this study was to compare pain-scores in three targeted treatment-strategies in JIA-patients and to identify characteristics predicting persistent pain.

    Authors: Katinka Spekking, Janneke Anink, Piroska de Boer, Sytske Anne Bergstra, J. Merlijn van den Berg, Dieneke Schonenberg-Meinema, Lisette W. A. van Suijlekom-Smit, Marion A. J. van Rossum, Yvonne Koopman-Keemink, Rebecca ten Cate, Cornelia F. Allaart, Daniëlle M. C. Brinkman and Petra C. E. Hissink Muller
    Citation: Pediatric Rheumatology 2023 21:90
  39. Granulomatosis with polyangiitis (GPA) is an autoimmune disease characterized by chronic vasculitis involving small to medium sized arteries, granulomatous inflammation of the upper and lower respiratory tract...

    Authors: Esraa Eloseily and Michael Henrickson
    Citation: Pediatric Rheumatology 2023 21:89
  40. Kikuchi-Fujimoto disease (KFD) is typically a benign, self-limiting inflammatory disease. The diagnosis of KFD can be challenging for nonspecific symptoms, laboratory or imaging findings. In this study, we aim...

    Authors: Tingyan He, Zixuan Shen, Jiayun Ling, Xiaona Zhu and Jun Yang
    Citation: Pediatric Rheumatology 2023 21:88
  41. IgA vasculitis (IgAV) is a small vessel vasculitis that is more common in childhood. Very limited evidence exists on patients who experience an atypical disease course. The aim of this study was to describe a ...

    Authors: Julien Marro, Chloe Williams, Clare E. Pain and Louise Oni
    Citation: Pediatric Rheumatology 2023 21:85
  42. Childhood Sjögren’s Disease (cSjD) is an underdiagnosed phenomenon with clinical and pathophysiological nuances in contrast to Sjögren’s Disease (SjD) in the adult population. While adults typically experience...

    Authors: Kristin Drew, René Kronlage, Seunghee Cha, Akaluck Thatayatikom and Thomas Schrepfer
    Citation: Pediatric Rheumatology 2023 21:83
  43. Growing evidence suggests that infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may trigger idiopathic inflammatory myopathies (IIM). Few studies have described individual juvenile I...

    Authors: Jessica Perfetto, Donna A. Yoo, Carolina Y. Tamashiro, Megan M. Perron, Natalia Vasquez-Canizares and Dawn M. Wahezi
    Citation: Pediatric Rheumatology 2023 21:82

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