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  1. Childhood Polyarteritis nodosa (PAN) is a systemic vasculitis with necrotizing inflammation of medium- and small-sized arteries. Disease evolution may be severe and refractory to standard treatment including p...

    Authors: Margaux Boistault, Mireia Lopez Corbeto, Pierre Quartier, Laura Berbel Arcobé, Ariadna Carsi Durall and Florence A. Aeschlimann
    Citation: Pediatric Rheumatology 2021 19:168
    Content type: Case Report Published on:

  2. The objective of this work was to describe magnetic resonance imaging (MRI) changes over time in inflammatory and structural lesions at the sacroiliac joint (SIJ) in children with spondyloarthritis (SpA) expos...

    Authors: Timothy G. Brandon, Rui Xiao, Rosemary G. Peterson, Nancy A. Chauvin, Michael L. Francavilla, David M. Biko, Dax G. Rumsey, Matthew L. Stoll and Pamela F. Weiss
    Citation: Pediatric Rheumatology 2021 19:167
    Content type: Research article Published on:

  3. Juvenile Idiopathic Arthritis (JIA) is a group of chronic heterogenous disorders that manifests as joint inflammation in patients aged <16 years. Globally, approximately 3 million children and young adults are...

    Authors: Sulaiman M. Al-Mayouf, Muna Al Mutairi, Kenza Bouayed, Sara Habjoka, Djohra Hadef, Hala M. Lotfy, Cristiaan Scott, Elsadeg M. Sharif and Nouran Tahoun
    Citation: Pediatric Rheumatology 2021 19:166
    Content type: Review Published on:

  5. The transition of health care from Pediatric to Adult providers for adolescents and young adults with chronic disease is associated with poor outcomes. Despite the importance of this transition, over 80% of th...

    Authors: Rebecca S. Overbury, Kelly Huynh, John Bohnsack, Tracy Frech and Aimee Hersh
    Citation: Pediatric Rheumatology 2021 19:164
    Content type: Research article Published on:

  6. Flares of juvenile idiopathic arthritis (JIA) have been described in the context of various infections. Flares of rheumatic diseases in adults have been described following infection with SARS-CoV-2 in several...

    Authors: Boris Hügle, Manuela Krumrey-Langkammerer and Johannes-Peter Haas
    Citation: Pediatric Rheumatology 2021 19:163
    Content type: Research article Published on:

  7. This study aimed to assess the baseline characteristics and clinical outcomes of coronavirus disease 2019 (COVID-19) in pediatric patients with rheumatic and musculoskeletal diseases (RMD) and identify the ris...

    Authors: Daniel Clemente, Clara Udaondo, Jaime de Inocencio, Juan Carlos Nieto, Pilar Galán del Río, Antía García Fernández, Jaime Arroyo Palomo, Javier Bachiller-Corral, Juan Carlos Lopez Robledillo, Claudia Millán Longo, Leticia Leon, Lydia Abasolo and Alina Boteanu
    Citation: Pediatric Rheumatology 2021 19:162
    Content type: Research article Published on:

  8. Mevalonate kinase deficiency (MKD) is a rare autoinflammatory condition caused by biallelic loss-of-function (LOF) mutations in mevalonate kinase (MVK) gene encoding the enzyme mevalonate kinase. Patients with MK...

    Authors: Ebun Omoyinmi, Dorota Rowczenio, Neil Sebire, Paul A. Brogan and Despina Eleftheriou
    Citation: Pediatric Rheumatology 2021 19:161
    Content type: Case Report Published on:

  10. Exercise has been suggested to prevent deterioration of health-related quality of life (HRQL) and overall health in pediatric rheumatologic diseases during the COVID-19 pandemic. Herein we describe the effects...

    Authors: Camilla Astley, Sofia Mendes Sieczkowska, Isabela Gouveia Marques, Bianca Pires Ihara, Livia Lindoso, Sofia Simão Martins Lavorato, Lucia Maria Arruda Campos, Rosa Maria Rodrigues Pereira, Adriana Maluf Elias, Nadia Emi Aikawa, Katia Kozu, Amanda Yuri Iraha, Tathiane Christine Franco, Hamilton Roschel, Ligia Bruni Queiroz, Guilherme Vanoni Polanczyk…
    Citation: Pediatric Rheumatology 2021 19:159
    Content type: Research article Published on:

  11. Juvenile idiopathic arthritis (JIA) is the leading chronic rheumatic disease in childhood. To achieve adherence to therapy, in-depth understanding of disease and treatment options are important.

    Authors: Christiane Reiser, Nina A. Zeltner, Beatrix Rettenbacher, Petra Baumgaertner, Martina Huemer and Christian Huemer
    Citation: Pediatric Rheumatology 2021 19:158
    Content type: Research article Published on:

  12. Kawasaki disease (KD) is a systemic vasculitis that predominantly affects medium-sized arteries. In addition to well-known coronary artery aneurysms (CAAs), peripheral systemic artery aneurysms (SAAs) have als...

    Authors: Chen Chu, Lan He, Yi-xiang Lin, Li-ping Xie and Fang Liu
    Citation: Pediatric Rheumatology 2021 19:157
    Content type: Case Report Published on:

  14. Children report that they do not participate in their healthcare as much as they want, despite having the lawful right to form their own views and the right to express those views freely in all matters affecti...

    Authors: Veronica Lundberg, Catharina Eriksson, Torbjörn Lind, Imelda Coyne and Anncristine Fjellman-Wiklund
    Citation: Pediatric Rheumatology 2021 19:156
    Content type: Research article Published on:

  16. Intra-articular venous malformations (IAVM) are rare benign vascular anomalies that usually affect young patients and most common locate in the knee. The terminology of these lesions is still ill-defined, as t...

    Authors: Federico Diomeda, Maria Santaniello, Giulia Bracciolini, Angelo Ravelli and Adele Civino
    Citation: Pediatric Rheumatology 2021 19:153
    Content type: Case Report Published on:

  17. Juvenile Idiopathic Arthritis (JIA) requires complex care that generate elevated costs, which results in a high economic impact for the family. The aim of this systematic review was to collect and cluster the ...

    Authors: Fernando García-Rodríguez, Augusto Gamboa-Alonso, Sol Jiménez-Hernández, Lucero Ochoa-Alderete, Valeria Alejandra Barrientos-Martínez, Neri Alejandro Alvarez-Villalobos, Gabriela Andrea Luna-Ruíz, Ingris Peláez-Ballestas, Ana Victoria Villarreal-Treviño, Manuel Enrique de la O-Cavazos and Nadina Rubio-Pérez
    Citation: Pediatric Rheumatology 2021 19:152
    Content type: Review Published on:

  19. The aim of the study was to investigate the relationship between the severity of typical clinical symptoms, severity of histopathological lesions in kidney biopsies in IgA vasculitis nephritis (IgAVN) and to p...

    Authors: Małgorzata Mizerska-Wasiak, Agnieszka Turczyn, Karolina Cichoń-Kawa, Jadwiga Małdyk, Monika Miklaszewska, Dorota Drożdż, Beata Bieniaś, Przemysław Sikora, Magdalena Drożyńska-Duklas, Aleksandra Żurowska, Maria Szczepańska and Małgorzata Pańczyk-Tomaszewska
    Citation: Pediatric Rheumatology 2021 19:150
    Content type: Research article Published on:

  20. Chronic anterior uveitis is a sight-threatening complication of juvenile idiopathic arthritis (JIA) and a primary contributor to long-term morbidity in people with JIA. Levels of knowledge about uveitis among ...

    Authors: Ashley M. Cooper, Elaine R. Flanagan, Tova Ronis, Baruch Goldberg, Ashley K. Sherman, Chelsey Smith and Gary N. Holland
    Citation: Pediatric Rheumatology 2021 19:149
    Content type: Research article Published on:

  22. Intravenous immunoglobulin (IVIG) resistance prediction is one of the primary clinical issues and study hotspots in KD. This study aimed to prospectively investigate the value of albumin-bilirubin grade (ALBI)...

    Authors: Yu Yan, Lina Qiao, Yimin Hua, Shuran Shao, Nanjun Zhang, Mei Wu, Lei Liu, Kaiyu Zhou, Xiaoliang Liu and Chuan Wang
    Citation: Pediatric Rheumatology 2021 19:147
    Content type: Research article Published on:

  23. Juvenile Idiopathic Inflammatory Myopathies (IIM) are a group of rare diseases that are heterogeneous in terms of pathology that can include proximal muscle weakness, associated skin changes and systemic invol...

    Authors: Meredyth G. Ll Wilkinson, Claire T. Deakin, Charalampia Papadopoulou, Despina Eleftheriou and Lucy R. Wedderburn
    Citation: Pediatric Rheumatology 2021 19:146
    Content type: Review Published on:

  24. The aetiology of juvenile idiopathic arthritis (JIA) is poorly understood. It has been shown that use of antibiotics is associated with JIA. However, whether the association is due to increased occurrence of i...

    Authors: Erik Kindgren and Johnny Ludvigsson
    Citation: Pediatric Rheumatology 2021 19:145
    Content type: Research article Published on:

  25. Pleural effusion in systemic lupus erythematous (SLE) is a common symptom, and recent studies demonstrated that IL-6 has a pivotal role in its pathogenesis.

    Authors: Arianna De Matteis, Emanuela Sacco, Camilla Celani, Andrea Uva, Virginia Messia, Rebecca Nicolai, Manuela Pardeo, Fabrizio De Benedetti and Claudia Bracaglia
    Citation: Pediatric Rheumatology 2021 19:144
    Content type: Case Report Published on:

  26. Although canakinumab has demonstrated efficacy in multiple trials in patients with periodic fever syndromes (PFS), the evidence on initiation of canakinumab among PFS patients in real world setting is not well...

    Authors: Peter Hur, Kathleen G. Lomax, Raluca Ionescu-Ittu, Ameur M. Manceur, Jipan Xie, Jordan Cammarota, Raju Gautam, Navneet Sanghera, Nina Kim and Alexei A. Grom
    Citation: Pediatric Rheumatology 2021 19:143
    Content type: Research article Published on:

  27. Autoinflammatory diseases (AID) are rare chronic conditions with high disease burden, affecting children and adults. Clinically and genetically confirmed, AID can be effectively treated with targeted cytokine ...

    Authors: Tatjana Welzel, Anna L. Wildermuth, Norbert Deschner, Susanne M. Benseler and Jasmin B. Kuemmerle-Deschner
    Citation: Pediatric Rheumatology 2021 19:142
    Content type: Research article Published on:

  28. The ACR 1997, SLICC 2012 and EULAR/ACR 2019 classification criteria were validated based on adult patients. To date, there are no classification criteria specific for children with SLE. The aim of the study is...

    Authors: Reem Abdwani, Eman Al Masroori, Eiman Abdullah, Safiya Al Abrawi and Ibrahim Al-Zakwani
    Citation: Pediatric Rheumatology 2021 19:141
    Content type: Research article Published on:

    The Correction to this article has been published in Pediatric Rheumatology 2021 19:165

  30. Surgeries for idiopathic uveitis and juvenile idiopathic arthritis-associated uveitis in children are complex because of the high risk of inflammatory postoperative complications. There is no consensus about t...

    Authors: Julie Molimard, Christine Pajot, Priscille Olle, Alexandre Belot, Pierre Quartier, Florence Uettwiller, Chloé Couret, Valentine Coste, Camille Costet, Bahram Bodaghi, Pascal Dureau, Marion Bailhache and Pascal Pillet
    Citation: Pediatric Rheumatology 2021 19:139
    Content type: Research article Published on:

  31. This case study documents the first familial case of Blau syndrome (BS) in Palestine characterized with mutation in CARD15/NOD2.

    Authors: Salam Iriqat, Mohammed Abu Safieh, Manuel Fatouleh and Abdulsalam Alkaiyat
    Citation: Pediatric Rheumatology 2021 19:138
    Content type: Case Report Published on:

  32. Consensus treatment plans have been developed for induction therapy of newly diagnosed proliferative lupus nephritis (LN) in childhood-onset systemic lupus erythematosus. However, patients who do not respond t...

    Authors: Mileka Gilbert, Beatrice Goilav, Joyce J. Hsu, Paul J. Nietert, Esra Meidan, Annabelle Chua, Stacy P. Ardoin, Scott E. Wenderfer, Emily von Scheven and Natasha M. Ruth
    Citation: Pediatric Rheumatology 2021 19:137
    Content type: Research article Published on:

  33. The importance of developmentally appropriate transitional care in young people with juvenile-onset rheumatic and musculoskeletal disease is well recognised. The Paediatric Rheumatology European Society (PReS)...

    Authors: Janet E. McDonagh, Rachel Tattersall, Jacqui Clinch, Joanne Swan, Helen E. Foster and Liza McCann
    Citation: Pediatric Rheumatology 2021 19:136
    Content type: Review Published on:

  34. Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatological disorder and is classified by subtype according to International League of Associations for Rheumatology criteria. Depending on...

    Authors: Lina N. Zaripova, Angela Midgley, Stephen E. Christmas, Michael W. Beresford, Eileen M. Baildam and Rachel A. Oldershaw
    Citation: Pediatric Rheumatology 2021 19:135
    Content type: Review Published on:

  35. Juvenile idiopathic arthritis (JIA), is the most common pediatric rheumatologic disorder with unknown etiology. Currently, no population-based data are available regarding the distribution of categories and fr...

    Authors: Sezgin Sahin, Ceyhun Acari, Hafize Emine Sonmez, Fatma Zehra Kilic, Erdal Sag, Hatice Adiguzel Dundar, Amra Adrovic, Selcan Demir, Kenan Barut, Yelda Bilginer, Betul Sozeri, Erbil Unsal, Seza Ozen and Ozgur Kasapcopur
    Citation: Pediatric Rheumatology 2021 19:134
    Content type: Research article Published on:

  38. We aimed to characterize etanercept (ETN) use in juvenile idiopathic arthritis (JIA) patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry.

    Authors: Timothy Beukelman, Aimee Lougee, Roland A. Matsouaka, David Collier, Dax G. Rumsey, Jennifer Schenfeld, Scott Stryker, Marinka Twilt and Yukiko Kimura
    Citation: Pediatric Rheumatology 2021 19:131
    Content type: Research article Published on:

  39. Juvenile idiopathic arthritis constitutes a significant cause of disability and quality of life impairment in pediatric and adult patients. The aim of this study was to ascertain clinical remission (CR) and su...

    Authors: Mireia Castillo-Vilella, Nuria Giménez, Jose Luis Tandaipan, Salvador Quintana and Consuelo Modesto
    Citation: Pediatric Rheumatology 2021 19:130
    Content type: Research article Published on:

  40. The curriculum for professionals working in paediatric rheumatology should include pain but it is unclear to what extent this currently occurs. The aim of this study was to identify pain-related curriculum con...

    Authors: Rebecca Rachael Lee, Janet E. McDonagh, Mark Connelly, Sarah Peters and Lis Cordingley
    Citation: Pediatric Rheumatology 2021 19:129
    Content type: Research article Published on:

  41. Juvenile-onset Fibromyalgia (JFM) is a chronic pain condition characterized by widespread musculoskeletal pain, fatigue, sleep difficulties, mood concerns, and other associated symptoms. Although diagnosed in ...

    Authors: Morgan Daffin, Mary K. Lynch-Milder, Robert C. Gibler, Caitlin Murray, Carly M. Green and Susmita Kashikar-Zuck
    Citation: Pediatric Rheumatology 2021 19:128
    Content type: Research article Published on:

  42. High-intensity glucocorticoid regimens are commonly used to induce and maintain remission in Juvenile Dermatomyositis but are associated with several adverse side-effects. Evidence-based treatment guidelines f...

    Authors: Amir B. Orandi, Lampros Fotis, Jamie Lai, Hallie Morris, Andrew J. White, Anthony R. French and Kevin W. Baszis
    Citation: Pediatric Rheumatology 2021 19:127
    Content type: Research article Published on:

  43. Mutations along PSTPIP1 gene are associated to two specific conditions, PAPA syndrome and PAMI syndrome, both autoinflammatory disorders associated to disturbances in cytoskeleton formation. Immunological aspe...

    Authors: Leonardo Oliveira Mendonça, Maria Teresa Terreri, Fabiane Mitie Osaku, Samar Freschi Barros, Karen Francine Köhler, Alex Isidoro Prado, Myrthes Toledo Barros, Jorge Kalil and Fabio Fernandes Morato Castro
    Citation: Pediatric Rheumatology 2021 19:126
    Content type: Research article Published on:

  46. Based on the recently developed ChRonic nonbacterial Osteomyelitis MRI Scoring tool (CROMRIS), we developed a radiological activity index (RAI-CROMRIS) to obtain a quantification of the overall bone involvemen...

    Authors: Martina Capponi, Denise Pires Marafon, Flaminia Rivosecchi, Yongdong Zhao, Manuela Pardeo, Virginia Messia, Laura Tanturri de Horatio, Paolo Tomà, Fabrizio De Benedetti and Antonella Insalaco
    Citation: Pediatric Rheumatology 2021 19:123
    Content type: Research article Published on:

  47. The impact of social determinants of health on children with polyarticular juvenile idiopathic arthritis (pJIA) is poorly understood. Prompt initiation of treatment for pJIA is important to prevent disease mor...

    Authors: Nayimisha Balmuri, William Daniel Soulsby, Victoria Cooley, Linda Gerber, Erica Lawson, Susan Goodman, Karen Onel and Bella Mehta
    Citation: Pediatric Rheumatology 2021 19:122
    Content type: Research article Published on:

  48. Mendelian susceptibility to mycobacterial disease (MSMD) is an inborn error of immunity, resulting in susceptibility to weakly virulent mycobacteria and other intramacrophagic pathogens. Rheumatologic manifest...

    Authors: Niusha Sharifinejad, Seyed Alireza Mahdaviani, Mahnaz Jamee, Zahra Daneshmandi, Afshin Moniri, Majid Marjani, Payam Tabarsi, Parisa Farnia, Mahsa Rekabi, Mazdak Fallahi, Seyedeh Atefeh Hashemimoghaddam, Masoumeh Mohkam, Jacinta Bustamante, Jean-Laurent Casanova, Davood Mansouri and Ali Akbar Velayati
    Citation: Pediatric Rheumatology 2021 19:121
    Content type: Case Report Published on:

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ISSN: 1546-0096