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  1. The American College of Rheumatology (ACR)/Childhood Arthritis and Rheumatology Research Alliance (CARRA) Mentoring Interest Group (AMIGO) is an inter-institutional mentorship program launched to target mentor...

    Authors: Kristen Hayward, Alexi Grom, Eyal Muscal, Peter A. Nigrovic, Kelly A. Rouster-Stevens, Kaveh Ardalan, Linda Hiraki and L. Nandini Moorthy
    Citation: Pediatric Rheumatology 2024 22:64
  2. The World Health Organisation Essential Medicines List (WHO EML) guides National Essential Medicines Lists and Standard Treatment Guidelines for clearly identified disease priorities especially in low- and mid...

    Authors: Waheba Slamang, Christiaan Scott and Helen E. Foster
    Citation: Pediatric Rheumatology 2024 22:63
  3. Many children with rheumatic and musculoskeletal diseases are unrecognized. Identifying these children requires health care provider awareness, knowledge, and skills to recognize disease features and how (and ...

    Authors: Jeanine McColl, Oscar Mwizerwa, Christiaan Scott, Shirley ML Tse and Helen E. Foster
    Citation: Pediatric Rheumatology 2024 22:60
  4. Systemic lupus erythematosus (SLE) is a life-threatening, chronic, autoimmune disease requiring long term subspecialty care due to its complex and chronic nature. Childhood-onset SLE (cSLE) is more severe than...

    Authors: Naira Ikram, Laura B. Lewandowski, Melissa H. Watt and Christiaan Scott
    Citation: Pediatric Rheumatology 2024 22:59
  5. Macrophage activation syndrome (MAS), an example of secondary hemophagocytic lymphohistiocytosis, is a potentially fatal complication of rheumatic diseases. We aimed to study the clinical and laboratory charac...

    Authors: Shuoyin Huang, Yingying Liu, Wu Yan, Tonghao Zhang, Panpan Wang, Meifang Zhu, Xiaohua Zhang, Peng Zhou, Zhidan Fan and Haiguo Yu
    Citation: Pediatric Rheumatology 2024 22:58
  6. Juvenile Dermatomyositis (JDM) is the leading cause of non-infectious inflammatory myopathy in children. It is a heterogeneous group of autoimmune diseases characterized by a variable combination of muscular, ...

    Authors: Khalila Nainia, Mohamed Amine Aouzal, Imane Ouafik, Mariyam Charhbili, Amal Bouchhab, Abdellatif Daoudi, Samira Tizki and Radia Chakiri
    Citation: Pediatric Rheumatology 2024 22:57
  7. Vitamin C deficiency, or scurvy, is rare but poses risks for children with poor diets, limited resources, or malabsorption issues. It may also be common in children with restrictive or selective dietary habits...

    Authors: Hanna L. Kassa, S. Singh, M. Douglas-Jones, Gill Schermbrucker, J De Lange, Frank Phoya, Claire Butters, Carol Hlela, Ashton Coetzee, Ebrahim Banderker and Kate Webb
    Citation: Pediatric Rheumatology 2024 22:56
  8. Systemic autoinflammatory disorders (SAIDs) represent a growing spectrum of diseases characterized by dysregulation of the innate immune system. The most common pediatric autoinflammatory fever syndrome, Perio...

    Authors: Y. Vyzhga, H. Wittkowski, V. Hentgen, S. Georgin-Lavialle, A. Theodoropoulou, S. Fuehner, M. Jesenak, J. Frenkel, E. Papadopoulou-Alataki, Jordi Anton, A. Nunzia Olivieri, J. Brunner, J. Sanchez, I. Koné-Paut, S. Fingerhutova, P. Pillet…
    Citation: Pediatric Rheumatology 2024 22:55
  9. To investigate the association between ultraviolet light index (UVI), as a marker for UV exposure, and seasonality with rash and systemic disease activity in youth with childhood-onset systemic lupus (cSLE) fr...

    Authors: Tamara I. Tanner, Ilir Agalliu, Dawn M. Wahezi and Tamar B. Rubinstein
    Citation: Pediatric Rheumatology 2024 22:54
  10. Etanercept has been studied in doses up to 0.8 mg/kg/week (max 50 mg/week) in juvenile idiopathic arthritis (JIA) patients. In clinical practice higher doses are used off-label, but evidence regarding the rela...

    Authors: Bastiaan T. van Dijk, Sytske Anne Bergstra, J. Merlijn van den Berg, Dieneke Schonenberg-Meinema, Lisette W.A. van Suijlekom-Smit, Marion A.J. van Rossum, Yvonne Koopman-Keemink, Rebecca ten Cate, Cornelia F. Allaart, Daniëlle M.C. Brinkman and Petra C.E. Hissink Muller
    Citation: Pediatric Rheumatology 2024 22:53
  11. Juvenile Idiopathic Arthritis (JIA) is a condition that occurs when individuals under the age of 16 develop arthritis that lasts for more than six weeks, and the cause is unknown. The development of JIA may be...

    Authors: Han Zhang, Xiao Ma, Wanlu Liu, Ze Wang, Zian Zhang, GuanHong Chen, Yingze Zhang, Tianrui Wang, Tengbo Yu and Yongtao Zhang
    Citation: Pediatric Rheumatology 2024 22:51
  12. Low-dose weekly methotrexate (MTX) is the mainstay of treatment in juvenile idiopathic arthritis. Unfortunately, a substantial part of patients has insufficient efficacy of MTX. A potential cause of this inade...

    Authors: Julia E. Möhlmann, Sytze de Roock, Annelies C. Egas, Evelien ter Weijden, Martijn J. H. Doeleman, Alwin D. R. Huitema, Matthijs van Luin and Joost F. Swart
    Citation: Pediatric Rheumatology 2024 22:52
  13. This study investigates the incidence of ocular involvement in Kawasaki disease (KD) and evaluates the relationship between ocular manifestations, laboratory findings, echocardiographic findings, and intraveno...

    Authors: Mohsen Jari and Hajar Esmaeili
    Citation: Pediatric Rheumatology 2024 22:50
  14. Immune checkpoint inhibitors (ICIs) have expanded the arsenal of cancer therapeutics over the last decade but are associated with a spectrum of immune-related adverse events (irAEs), including inflammatory art...

    Authors: John A. Storwick, Herman Tam, Daniel G. Rosenbaum and Kristin Houghton
    Citation: Pediatric Rheumatology 2024 22:49
  15. Measurement of the circulating levels of long-non-coding RNAs (lncRNAs) in lupus nephritis (LN) patients could dramatically explore more insights about the disease pathogenesis. Hence, we aimed to quantify the...

    Authors: Mohamed M. Zedan, Ali Sobh, Alshimaa Magdy, Mai S. Korkor, Zeinab R. Attia, Nada Khaled, Yousra Sadeq, Ahmed Hazem El-Nagdy, Ahmed E. Taha, Mohamed Ahmed Noureldin, Mohamed Taman, Doaa Mosad Mosa and Marwa H. Elnagdy
    Citation: Pediatric Rheumatology 2024 22:48
  16. Juvenile idiopathic arthritis (JIA) is the most prevalent rheumatic disease in children, and the inflammatory process is widely studied, primarily characterized by its impact on joint health. Emerging evidence...

    Authors: Lillemor Berntson, Andreas Elfving, Alice Gabrielsson Samuelsson, Anders Öman and Fariborz Mobarrez
    Citation: Pediatric Rheumatology 2024 22:47
  17. Adolescents with juvenile idiopathic arthritis (JIA) tend to engage in less physical activity than their typically developing peers. Physical activity is essential for bone development and reduced physical act...

    Authors: Egi Vasil, Colleen M. Nesbitt, Clodagh Toomey, Gregor Kuntze, Shane Esau, Carolyn A. Emery and Leigh Gabel
    Citation: Pediatric Rheumatology 2024 22:45
  18. To investigate the psychosocial burden in children and adolescents with juvenile rheumatic diseases during the COVID-19 pandemic.

    Authors: Claudia Sengler, Jens Klotsche, Malthe Jessen Pedersen, Martina Niewerth, Julia Göldel, Daniel Windschall, Johannes-Peter Haas, Frank Dressler, Ralf Trauzeddel, Anton Hospach, Frank Weller-Heinemann, Stefanie Lanzinger, Clemens Kamrath, Reinhard W. Holl, Petra Warschburger and Kirsten Minden
    Citation: Pediatric Rheumatology 2024 22:44
  19. Kawasaki disease has been described across the globe, although publications from Africa are limited. To our knowledge, there are no publications on Kawasaki disease from Kenya, which triggered this report.

    Authors: A. Migowa, CM. Njeru, E. Were, T. Ngwiri, I. Colmegna, C. Hitchon and R. Scuccimarri
    Citation: Pediatric Rheumatology 2024 22:43
  20. Intravenous immunoglobulin (IVIG) is the primary treatment for Kawasaki disease (KD). However, 10–20% of KD patients show no response to IVIG treatment, making the early prediction of IVIG resistance a key foc...

    Authors: Jue Liu, Xingguang Chen, Minling Yang, Fangfang Shen, Feng Zhu, Jian Jin and Yiqun Teng
    Citation: Pediatric Rheumatology 2024 22:42
  21. Temporomandibular joint (TMJ) involvement is an often underrecognized complication of juvenile idiopathic arthritis (JIA) that can cause decreased mandibular growth, altered facial morphology, and orofacial pa...

    Authors: Anna Costello, Marinka Twilt and Melissa A. Lerman
    Citation: Pediatric Rheumatology 2024 22:41
  22. Rheumatic diseases can seriously impact children’s general health, development, and growth. However, due to a lack of resources, paediatric rheumatology is a largely underdeveloped speciality in many African n...

    Authors: Dzifa Dey, Bright Katso, Afia Baah, Saudatu Isaaka and Emmanuella Amoako
    Citation: Pediatric Rheumatology 2024 22:40
  23. Physical active lifestyles are essential throughout growth and maturation and may offer potential preventive and therapeutic benefit in patients with juvenile idiopathic arthritis (JIA). Insufficient physical ...

    Authors: Florian Milatz, Sandra Hansmann, Jens Klotsche, Martina Niewerth, Tilmann Kallinich, Frank Dressler, Johannes-Peter Haas, Rainer Berendes, Gerd Horneff, Markus Hufnagel, Frank Weller-Heinemann, Daniel Windschall, Ralf Trauzeddel, Moritz Klaas, Hermann Girschick, Prasad T. Oommen…
    Citation: Pediatric Rheumatology 2024 22:39
  24. Systemic juvenile idiopathic arthritis (sJIA) is a severe form of juvenile arthritis that is characterized by chronic joint inflammation and systemic symptoms such as fever, rash, and organ involvement. Anti-I...

    Authors: Lingzhi Qiu, Le Ma, Yifan Xie, Jing Jin, Yuting Pan, Shumin Li, Zhidan Fan and Haiguo Yu
    Citation: Pediatric Rheumatology 2024 22:38
  25. Multicentric carpotarsal osteolysis (MCTO) is a rare genetic disorder characterized by the progressive loss of bone in the hands, feet, and other skeletal structures. It presents with symptoms that may resembl...

    Authors: Xianfei Gao, Xiang Fang, Danping Huang, Song Zhang and Huasong Zeng
    Citation: Pediatric Rheumatology 2024 22:37
  26. Biomarkers may be useful in monitoring disease activity in juvenile idiopathic arthritis (JIA). With new treatment options and treatment goals in JIA, there is an urgent need for more sensitive and responsive ...

    Authors: Lena Cetrelli, Anette Lundestad, Elisabet G. Gil, Johannes Fischer, Josefine Halbig, Paula Frid, Oskar Angenete, Annika Rosén, Karin B. Tylleskär, Keijo Luukko, Ellen Nordal, Anne N. Åstrøm, Marit S. Skeie, Astrid Kamilla Stunes, Athanasia Bletsa, Abhijit Sen…
    Citation: Pediatric Rheumatology 2024 22:36
  27. Juvenile idiopathic arthritis (JIA) is a type of chronic childhood arthritis with complex pathogenesis. Immunological studies have shown that JIA is an acquired self-inflammatory disease, involving a variety o...

    Authors: Longhao Chen, Xingchen Zhou, Chao Yang, Hong Jiao Wu, Yu Tian, Shuangwei Hong, Huijie Hu, Kaizheng Wang, Shuang Wu, Zicheng Wei, Tao Li, Yuanshen Huang, Zihan Hua, Qiong Xia, Xiao Jie Chen, Zhizhen Lv…
    Citation: Pediatric Rheumatology 2024 22:35
  28. Chronic non-bacterial osteomyelitis (CNO) is a rare, non-infection- related inflammatory disorder that affects children and teens. Clinical manifestations of CNO range widely from moderate, time-limited, monof...

    Authors: Samar Tharwat and Mohammed Kamal Nassar
    Citation: Pediatric Rheumatology 2024 22:34
  29. Little is known about the efficacy and safety of exercise training on juvenile idiopathic arthritis (JIA). This study aims to investigate the effect of exercise on health, quality of life, and different exerci...

    Authors: Wen-yu Liu, Hui-min Li, Hao Jiang and Wen-kui Zhang
    Citation: Pediatric Rheumatology 2024 22:33
  30. A better understanding of the pathogenesis of polyarticular juvenile idiopathic arthritis (polyJIA) is needed to aide in the development of data-driven approaches to guide selection between therapeutic options...

    Authors: Stephanie Wood, Justin Branch, Priscilla Vasquez, Marietta M. DeGuzman, Amanda Brown, Anna Carmela Sagcal-Gironella, Saimun Singla, Andrea Ramirez and Tiphanie P. Vogel
    Citation: Pediatric Rheumatology 2024 22:32
  31. Enthesitis/spondylitis-related arthritis (ERA) is a type of juvenile idiopathic arthritis (JIA) frequently associated with HLA-B27. In sub-Saharan Africa, HLA-B27-positive ERA hasn’t been the subject of a spec...

    Authors: Mounib M. Sabounji, Aïssatou Ndiaye and Saïdou Diallo
    Citation: Pediatric Rheumatology 2024 22:31
  32. Stress in patients with Juvenile Idiopathic Arthritis (JIA) has been found to be associated with orofacial pain, psychological distress, jaw dysfunction and loss of daily activities in a cross-sectional study....

    Authors: Alexandra Dimitrijevic Carlsson, Kerstin Wahlund, Erik Kindgren, Martina Frodlund and Per Alstergren
    Citation: Pediatric Rheumatology 2024 22:30
  33. Eosinophilic fasciitis (EF) is a rare disease characterized by skin induration and musculoskeletal abnormalities. Diagnostic criteria for EF are based on adult populations. There is a need to expand the litera...

    Authors: Leigh A. Stubbs, Oluwaseun Ogunbona, Emily Beil, Vibha Szafron, Adekunle Adesina, Sara Anvari, Jamie Lai, Andrea Ramirez, Matthew G. Ditzler and Marietta DeGuzman
    Citation: Pediatric Rheumatology 2024 22:29
  34. A structured transition of adolescents and young adults with chronic autoinflammatory and autoimmune disorders from the pediatric to the adult health care system is important. To date, data on the time, proces...

    Authors: Daniela Choukair, Christian Patry, Ronny Lehmann, Dorothea Treiber, Georg F. Hoffmann, Corinna Grasemann, Normi Bruck, Reinhard Berner, Peter Burgard, Hanns-Martin Lorenz and Burkhard Tönshoff
    Citation: Pediatric Rheumatology 2024 22:28
  35. Authors: Oluwatunmise A. Fawole, Michelle V. Reed, Julia G. Harris, Aimee Hersh, Martha Rodriguez, Karen Onel, Erica Lawson, Tamar Rubinstein, Kaveh Ardalan, Esi Morgan, Anne Paul, Judy Barlin, R. Paola Daly, Mitali Dave, Shannon Malloy, Shari Hume…
    Citation: Pediatric Rheumatology 2024 22:27

    The original article was published in Pediatric Rheumatology 2021 19:19

  36. There is a growing interest concerning the relationship between obesity and several medical conditions and inflammation. Nevertheless, there is a lack of studies regarding body mass index (BMI) among patients ...

    Authors: Anna-Kaisa Tuomi, Katariina Rebane, Ellen Dalen Arnstad, Lillemor Berntson, Anders Fasth, Mia Glerup, Troels Herlin, Hannu Kautiainen, Ellen Nordal, Suvi Peltoniemi, Marite Rygg, Veronika Rypdal, Marek Zak and Kristiina Aalto
    Citation: Pediatric Rheumatology 2024 22:25
  37. Germline heterozygous gain-of-function (GOF) mutations in the PIK3CD gene lead to a rare primary immunodeficiency disease known as activated phosphoinositide 3-kinase (PI3K) δ syndrome type 1(APDS1). Affected pat...

    Authors: Peiwei Zhao, Juan Huang, Huicong Fu, Jiali Xu, Tianhong Li, Xiankai Zhang, Qingjie Meng, Lei Zhang, Li Tan, Wen Zhang, Hebin Chen, Xiaoxia Lu, Yan Ding and Xuelian He
    Citation: Pediatric Rheumatology 2024 22:24
  38. Kawasaki disease (KD) is an acute systemic vasculitis of unknown etiology that affects infants and young children but is extremely rare in neonates, especially afebrile KD. We present a case of KD without feve...

    Authors: Mingjun Shen, Die Liu, Fang Ye, Jing Zhang and Jun Wang
    Citation: Pediatric Rheumatology 2024 22:23
  39. Juvenile Idiopathic Arthritis (JIA) Associated Uveitis (JIA-U) remains one of the most serious complications of JIA in children. Historically, pediatric JIA is diagnosed by an Optometrist or Ophthalmologist; h...

    Authors: Kaleo Ede, Michael Shishov, Elisa Wershba, Nikita Goswami, Sabrina Gorry, Malin Joseph, Lucia Mirea and James O’Neil
    Citation: Pediatric Rheumatology 2024 22:22
  40. H Syndrome is a rare genetic condition caused by biallelic pathogenic variants in the SLC29A3 gene. It is characterized by a wide range of clinical manifestations, many of which are related to the immune-rheum...

    Authors: Alessandra Tesser, Erica Valencic, Valentina Boz, Gianluca Tornese, Serena Pastore, Manuela Zanatta and Alberto Tommasini
    Citation: Pediatric Rheumatology 2024 22:21
  41. The defective clearance of apoptotic bodies in juvenile-onset systemic lupus erythematosus (jSLE) potentially leads to the persistence of autoreactive lymphocytes and the perpetuation of the autoimmune respons...

    Authors: Eman Eissa, Rania Kandil, Dalia Dorgham, Raghda Ghorab and Naglaa Kholoussi
    Citation: Pediatric Rheumatology 2024 22:20
  42. Hypertension caused by vascular Behcet’s disease (BD) is an important prognostic factor of paediatric BD. However, much less is known about its clinical features. The objective of this study was to investigate...

    Authors: Xinning Wang, Zhixuan Zhou, Jianguo Li, Gaixiu Su and Xiaohui Li
    Citation: Pediatric Rheumatology 2024 22:19
  43. Systemic juvenile idiopathic arthritis (SJIA) is a form of childhood arthritis with clinical features such as fever, lymphadenopathy, arthritis, rash, and serositis. It seriously affects the growth and develop...

    Authors: Pan Ding, Yi Du, Xinyue Jiang, Huajian Chen and Li Huang
    Citation: Pediatric Rheumatology 2024 22:18
  44. Childhood systemic lupus erythematosus (cSLE) has been considered as a polygenic autoimmune disease; however, a monogenic lupus-like phenotype is emerging with the recent recognition of several related novel h...

    Authors: Patricia Morán-Álvarez, Alessandra Gianviti, Francesca Diomedi-Camassei, Monia Ginevrino, Fabrizio de Benedetti and Claudia Bracaglia
    Citation: Pediatric Rheumatology 2024 22:17

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