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Table 3 Adverse events associated with IVIG + anakinra treatment in MIS-C patients

From: Clinical outcomes and safety of anakinra in the treatment of multisystem inflammatory syndrome in children: a single center observational study

Adverse event

IVIG monotherapy

(n = 14)

IVIG + anakinra without CS (n = 25)

IVIG + anakinra with CS (n = 9)

p-value

Elevated LFTs (n %)

2, 14%

6, 24%

7, 67%

0.008*

Neutropenia (n %)

1, 7%

5, 20%

3, 33%

0.36

Hemolytic anemia (n %)

1, 7%

1, 4%

1, 11%

0.73

Anaphylaxis (n %)

0, 0%

0, 0%

0, 0%

N/A

Rash (n %)

0, 0%

2, 8%

0, 0%

0.42

Re-hospitalization (n %)

0, 0%

0, 0%

0, 0%

N/A