Fig. 1

Clinical outcomes associated with treatment of MIS-C patients

Effects of anakinra on fever and cardiac function in MIS-C patients. Fever in patients given IVIG monotherapy or IVIG + anakinra starting from admission (A) and in IVIG + anakinra patients treated with or without CS (B) are shown. LVEF (C) and cardiac strain (D) are shown among the treatment groups. Dotted lines denote the cut-off ranges for normal LVEF (55%) and cardiac strain (-21.4). Data were analyzed by log rank test (A and B) or non-parametric two-tailed Wilcoxon matched pairs signed rank test (C and D), and a p-value < 0.05 was considered statistically significant