- Poster presentation
- Open Access
Accuracy of preliminary remission criteria some JIA category
Pediatric Rheumatology volume 6, Article number: P105 (2008)
To evaluate disease course in juvenile idiopathic arthritis (JIA) by applying newly developed preliminary definitions of remission, to assess probability of relapse of disease. Charts of patients with JIA followed since 1970 were reviewed. First episode of remission off medication status, as defined by Wallace et al., has been focused. The cohort included 761 patients (67.8% females, 32.2% males) with JIA. Mean disease onset age (± SD) was 6.25 ± 4.4 years (range 0.5–15.9). Disease mean duration to last visit was 10.02 ± 4.31 years. Follow up mean period was 7.6 ± 6.4 years (range 1.5–35 years). A total of 263 (34.56%) patients achieved remission according to criteria (persistent oligoarthritis 42.9%, extended oligoarthritis 13.1%, seronegative polyarthritis 22.4%, systemic arthritis 33.7%, enthesitis related arthritis (ERA) plus juvenile psoriatic arthritis (JPsA) 33.4%. No patients with seropositive polyarthritis achieved remission status (p < 0.001). In remitted patients the mean survival function (± SEM) before relapse calculated by life table survival curve was of 20.9 (± 1.3) months overall: 21.7 (± 0.46) in persistent oligoarthritis, 25.0 (± 6.6) in extended oligoarthritis, 26.7 (± 13.2) in seronegative polyarthritis and 17.6 (± 2.44) in ERA+JPsA. The log rank test did not show a significant difference between the JIA categories survival curves (p = 0.1). In our cohort about one-third of cases obtained a remission episode in 4 decades of observation. Finally, if a remission was achieved, the mean duration before a relapse was about 20 months.
Rights and permissions
Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( https://creativecommons.org/licenses/by/2.0 ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
About this article
Cite this article
Fantini, F., Salmaso, A., Gerloni, V. et al. Accuracy of preliminary remission criteria some JIA category. Pediatr Rheumatol 6 (Suppl 1), P105 (2008). https://doi.org/10.1186/1546-0096-6-S1-P105
- Juvenile Idiopathic Arthritis
- Psoriatic Arthritis
- Remission Status
- Remission Criterion
- Preliminary Definition