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Table 3 Comparison of effects of exercise training between treatment groups

From: Exercise in children with joint hypermobility syndrome and knee pain: a randomised controlled trial comparing exercise into hypermobile versus neutral knee extension

Outcome measure

Neutral training group (n=14)

Hypermobile training group (n=11)

Difference in change scores between groups

P value

Cohen’s D

 

Baseline mean (SD)

Post-treatment mean (SD)

Mean change

Baseline mean (SD)

Post-treatment mean (SD)

Mean change

     
       

Mean difference (H-N)

Lower bound of 95% CI

Upper bound of 95% CI

  

Primary Outcome Measures

Child’s report of mean knee pain over the week 1

40.04 (16.59)

20.14 (18.37)

−19.9

38.55 (16.89)

29.36 (17.99)

−9.19

10.71

−7.9

29.33

0.246

0.61

Child’s report of maximum knee pain over the week 1

57.68 (23.12)

35.64 (28.57)

−22.04

53.23 (23.55)

39.18 (27.21)

−14.05

7.99

−14.66

30.64

0.473

0.31

Secondary Outcome Measures

Child Reported Measures

PGIC2

0.29 (1.14)

1.71 (0.99)

1.43

0.18 (0.87)

1.82 (0.75)

1.64

0.21

−0.81

1.22

0.675

0.22

CHAQ 383

−0.13 (0.44)

−0.01 (0.60)

0.12

0.04 (0.71)

0.05 (0.72)

0.02

0.10

−0.25

0.45

0.552

0.16

Physical Measures

Overall thigh strength (N)

4.02 (1.72)

4.9 (2.17)

0.88

4.38 (2.37)

5.59 (1.45)

1.21

0.33

−1.66

1

0.608

0.17

No. of flights of stairs ran in 2 minutes

16.32 (5.00)

20.11 (5.52)

3.79

20.88 (6.69)

20.55 (5.44)

−0.33

−4.12

0.301

−8.523

0.118

0.73

Parent Reported Measures (CHQ-PF50) 4

Physical Summary Score

32.01 (11.86)

42.08 (10.81)

10.07

41.61 (14.96)

43.91 (15.05)

2.3

−7.77

−14.99

−0.55

0.037*

0.59

Psychosocial Summary Score

46.35 (12.26)

45.41 (13.49)

−0.94

46.29 (8.95)

54.41 (4.42)

8.12

9.06

2.66

15.47

0.009*

0.83

  1. 1 Using the 0 - 100 mm VAS.
  2. 2 Patient’s Global Impression of Change (PGIC).
  3. 3 Child Health Assessment Questionnaire – 38 question version (CHAQ-38).
  4. 4 Child Health Questionnaire (CHQ).
  5. *p<0.05 statistically significant.