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Table 4 Comparison between active and inactive lupus nephritis (LN) regarding clinical presentations and laboratory findings

From: Long noncoding RNAs (CTC-471J1.2, NeST) as epigenetic risk factors of active juvenile lupus nephritis: a case-control study

Parameter

Inactive LN (n = 45)

Active LN (n = 16)

Test of Significance

Sex

 Male

34 (75.6)

12 (75)

FET

P = 1

 Female

11 (24.4)

4 (25)

Fever

 Absent

29 (64.4)

7 (43.8)

x2 = 2.1

P = 0.15

 Present

16 (35.6)

9 (56.3)

Mucocutaneous

 Absent

23 (51)

5 (31.2)

X2 = 1.87

P = 0.17

 Present

22 (49)

11 (68.8)

Arthritis

 Absent

32 (71)

11 (68.8)

FET

P = 1

 Present

13 (29)

5 (31.2)

Serositis

 Absent

32 (71)

10 (62.5)

FET

P = 0.54

 Present

13 (29)

6 (37.5)

Vasculitis

 Absent

45 (100)

14 (87.5)

FET

P = 0.06

 Present

0.0

2 (12.5)

Medications

 2 medications

16 (35.6)

2 (12.5)

FET

P = 0.11

 > 2 medications

29 (64.4)

14 (87.5)

Anemia

 Absent

33 (73.3)

15 (93.8)

FET

P = 0.15

 Present

12 (26.7)

1 (6.3)

Leucopenia

 Absent

42 (93.3)

16 (100)

FET

0.56

 Present

3 (6.7)

0.0

Thrombocytopenia

 Absent

44 (97.8)

15 (93.8)

FET

P = 0.45

 Present

1 (2.2)

1 (6.3)

Liver function test

 Normal

42 (93.3)

14 (87.5)

FET

P = 0.6

 Elevated

3 (6.7)

2 (12.5)

APL antibodies

 Negative

36 (80)

14 (87.5)

FET

P = 0.7

 Positive

9 (20)

2 (12.5)

  1. Values reported as percentile
  2. P > 0.05 is considered statistically not significant
  3. Abbreviations: n Number, LN Lupus nephritis, APL Anti-phospholipids antibodies, FET Fischer exact test, X2 Chi square test