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  1. Social determinants of health (SDH) greatly influence outcomes during the first year of treatment in rheumatoid arthritis, a disease similar to polyarticular juvenile idiopathic arthritis (pJIA). We investigat...

    Authors: William Daniel Soulsby, Nayimisha Balmuri, Victoria Cooley, Linda M. Gerber, Erica Lawson, Susan Goodman, Karen Onel and Bella Mehta
    Citation: Pediatric Rheumatology 2022 20:18
  2. Pediatric antiphospholipid syndrome (APS) is a thromboinflammatory disease characterized by the presence of circulating antiphospholipid antibodies and either thrombotic events or pregnancy morbidity. The obje...

    Authors: Jacqueline A. Madison, Kelsey Gockman, Claire Hoy, Ajay Tambralli, Yu Zuo and Jason S. Knight
    Citation: Pediatric Rheumatology 2022 20:17
  3. Macrophage activation syndrome (MAS) is a severe and under-recognized complication of rheumatologic diseases. We describe a patient who presented with rapidly progressive, refractory MAS found to have anti-MD...

    Authors: J. Alex Stewart, Theresa Price, Sam Moser, Dolores Mullikin and Angela Bryan
    Citation: Pediatric Rheumatology 2022 20:16
  4. Patients with juvenile chronic inflammatory systemic diseases (jCID) are vulnerable to many circumstances when transitioning to adult-centered healthcare; this increases the burden of disease and worsen their ...

    Authors: Fernando García-Rodríguez, Karina Raygoza-Cortez, Lesli Moreno-Hernandez, Rodrigo García-Pérez, Leticia Elizabeth Garza Lopez, Ana Cecilia Arana-Guajardo, Joel Omar Jáquez-Quintana, Ana Victoria Villarreal-Treviño, Manuel Enrique de la O-Cavazos and Nadina Rubio-Pérez
    Citation: Pediatric Rheumatology 2022 20:15
  5. While the general relationship between ACEs and the development of chronic pain has become increasingly clear, how ACEs may shape a child’s clinical presentation with regards to chronic pain has yet to be full...

    Authors: Maitry Sonagra, Jeremy Jones, Mackenzie McGill and Sabrina Gmuca
    Citation: Pediatric Rheumatology 2022 20:14
  6. Describe the frequency of thrombotic and non-thrombotic clinical manifestations, laboratory, treatment and prognosis in patients with pediatric primary antiphospholipid syndrome.

    Authors: Alfonso-Ragnar Torres-Jimenez, Virginia Ramirez-Nova, Adriana Ivonne Cespedes-Cruz, Berenice Sanchez-Jara, Alejandra Velazquez-Cruz, Vilma Carolina Bekker-Méndez and Francisco Xavier Guerra-Castillo
    Citation: Pediatric Rheumatology 2022 20:13
  7. In comparison with the general population, adolescents with juvenile idiopathic arthritis (JIA) are at higher risk for morbidity and mortality. However, limited evidence is available about this condition’s und...

    Authors: Kimberly A. Lewis, Nico Osier, Ruy Carrasco, Jennifer Chiou, Patricia Carter, Alexandra Garcia, Elena Flowers, Efstathios D. Gennatas, Christina Nguyen, Ambreen Rana, Sharon A. Brown and Stefano Tiziani
    Citation: Pediatric Rheumatology 2022 20:12
  8. Nailfold capillary microscopy (NCM) is a cornerstone in the diagnosis of Systemic Sclerosis (SSc) in adulthood. Although Raynaud’s phenomenon (RP) is very common in childhood, studies on diagnostic methods to ...

    Authors: Claudette A. Farenhorst, Anniek M. Roon, Anne I. Gessel, Alja J. Stel, Hendrika Bootsma, Wineke Armbrust and Douwe J. Mulder
    Citation: Pediatric Rheumatology 2022 20:11
  9. The translation of research findings into clinical practice is challenging, especially fields like in pediatric rheumatology, where the evidence base is limited, there are few clinical trials, and the conditio...

    Authors: Cagri Yildirim-Toruner, Rajdeep Pooni, Y. Ingrid Goh, Emily Becker-Haimes, James W. Dearing, Maria E. Fernandez, Esi M. Morgan, Gareth Parry, Jon M. Burnham, Stacy P. Ardoin, Fatima Barbar-Smiley, Joyce C. Chang, Peter Chiraseveenuprapund, Vincent Del Gaizo, Guy Eakin, Lisa C. Johnson…
    Citation: Pediatric Rheumatology 2022 20:10
  10. An association of different autoimmune diseases is suspected. In juvenile idiopathic arthritis (JIA), only few and partially conflicting data on the co-existence of other autoimmune disorders are available. Th...

    Authors: Caroline Schulz, Sabrina Fuehner, Bernhard Schlüter, Manfred Fobker, Claudia Sengler, Jens Klotsche, Martina Niewerth, Kirsten Minden and Dirk Foell
    Citation: Pediatric Rheumatology 2022 20:8
  11. In women with autoimmune rheumatic disorders (ARD), pregnancy complications or postpartum events are more frequent compared to the general population. Transplacental autoantibodies or cytokines influence vario...

    Authors: Soo Yeun Sim, Hye Yeon Choi, Min Ho Jung, Soo Young Lee, Jung Woo Rhim, Hyun Mi Kang and Dae Chul Jeong
    Citation: Pediatric Rheumatology 2022 20:7
  12. Few published data describe how joint involvement, the most prevalent extraintestinal manifestation, affects quality of life (QoL) of children with Crohn’s disease (CD). Arthritis and arthralgia rates in pedia...

    Authors: Beata Derfalvi, Kriszta Katinka Boros, Doloresz Szabo, Gabor Bozsaki, Aron Cseh, Gabor Rudas, Katalin Eszter Muller and Gabor Veres
    Citation: Pediatric Rheumatology 2022 20:6
  13. Juvenile idiopathic arthritis (JIA) is the most common childhood rheumatic disease. Intra-articular corticosteroids joint injection (IAJI), with triamcinolone hexacetonide (TH) or triamcinolone acetonide (TA),...

    Authors: Shiri Rubin, Orly Ohana, Ori Goldberg, Orit Peled, Yulia Gendler, Zohar Habot-Wilner, Yoel Levinsky, Rotem Tal, Liora Harel and Gil Amarilyo
    Citation: Pediatric Rheumatology 2022 20:5
  14. Growth impairment is the most common complication in patients with childhood-onset systemic lupus erythematosus (cSLE). There are limited data on risk factors affecting growth development in Asian patients wit...

    Authors: Lalita Ponin, Preamrudee Poomthavorn, Kwanchai Pirojsakul, Butsabong Lerkvaleekul, Sirisucha Soponkanaporn, Niyata Chitrapazt and Soamarat Vilaiyuk
    Citation: Pediatric Rheumatology 2022 20:4
  15. Juvenile idiopathic arthritis (JIA) is a cluster of autoimmune rheumatic diseases occurring in children 16 years of age or less. While it is well-known that pain may be experienced during inflammatory and non-...

    Authors: Hanne Van Der Heijden, Benoit Fatou, Diana Sibai, Kacie Hoyt, Maria Taylor, Kin Cheung, Jordan Lemme, Mariesa Cay, Benjamin Goodlett, Jeffery Lo, Melissa M. Hazen, Olha Halyabar, Esra Meidan, Rudy Schreiber, Camilo Jaimes, Kirsten Ecklund…
    Citation: Pediatric Rheumatology 2022 20:3
  16. The aim of this study was to evaluate demographic, clinical, laboratory, imaging, histopathology characteristics, and treatment responses of children with Chronic nonbacterial osteomyelitis (CNO).

    Authors: Le Ma, Haimei Liu, Hanyun Tang, Zhiyong Zhang, Lixia Zou, Haiguo Yu, Li Sun, Xiaozhong Li, Xuemei Tang and Meiping Lu
    Citation: Pediatric Rheumatology 2022 20:1
  17. This study aimed to perform an immunoprofiling of systemic juvenile idiopathic arthritis (sJIA) in order to define biomarkers of clinical use as well as reveal new immune mechanisms.

    Authors: Heshuang Qu, Erik Sundberg, Cecilia Aulin, Manoj Neog, Karin Palmblad, Anna Carin Horne, Fredrik Granath, Alexandra Ek, Erik Melén, Mia Olsson and Helena Erlandsson Harris
    Citation: Pediatric Rheumatology 2021 19:173
  18. Multisystem Inflammatory Syndrome in Children (MIS-C) is a rare hyperinflammatory condition that occurs following SARS-CoV-2 infection. There is a paucity of research describing risk factors, optimal managemen...

    Authors: Jonathan Shabab, Allysen Dubisky, Ambaris Singh, Megan Crippen, Khalid Abulaban and Aileen Aldrich
    Citation: Pediatric Rheumatology 2021 19:172
  19. During the Coronavirus disease 2019 pandemic, ambulatory pediatric rheumatology healthcare rapidly transformed to a mainly telehealth model. However, pediatric patient and caregiver satisfaction with broadly d...

    Authors: Lindsay N. Waqar-Cowles, John Chuo, Pamela F. Weiss, Sabrina Gmuca, Marianna LaNoue and Jon M. Burnham
    Citation: Pediatric Rheumatology 2021 19:170
  20. Precision health in adolescents relies on the successful collection of data and biospecimens from an adequately sized sample of cases and comparison group(s), often healthy controls, to answer the research que...

    Authors: Kimberly A. Lewis, Shelby Brooks, Ruy Carrasco, Patricia Carter, Alexandra Garcia, Jennifer Chiou, Christina Nguyen, Ambreen Rana, Sharon A. Brown, Stefano Tiziani and Nico Osier
    Citation: Pediatric Rheumatology 2021 19:169
  21. Childhood Polyarteritis nodosa (PAN) is a systemic vasculitis with necrotizing inflammation of medium- and small-sized arteries. Disease evolution may be severe and refractory to standard treatment including p...

    Authors: Margaux Boistault, Mireia Lopez Corbeto, Pierre Quartier, Laura Berbel Arcobé, Ariadna Carsi Durall and Florence A. Aeschlimann
    Citation: Pediatric Rheumatology 2021 19:168
  22. The objective of this work was to describe magnetic resonance imaging (MRI) changes over time in inflammatory and structural lesions at the sacroiliac joint (SIJ) in children with spondyloarthritis (SpA) expos...

    Authors: Timothy G. Brandon, Rui Xiao, Rosemary G. Peterson, Nancy A. Chauvin, Michael L. Francavilla, David M. Biko, Dax G. Rumsey, Matthew L. Stoll and Pamela F. Weiss
    Citation: Pediatric Rheumatology 2021 19:167
  23. Juvenile Idiopathic Arthritis (JIA) is a group of chronic heterogenous disorders that manifests as joint inflammation in patients aged <16 years. Globally, approximately 3 million children and young adults are...

    Authors: Sulaiman M. Al-Mayouf, Muna Al Mutairi, Kenza Bouayed, Sara Habjoka, Djohra Hadef, Hala M. Lotfy, Cristiaan Scott, Elsadeg M. Sharif and Nouran Tahoun
    Citation: Pediatric Rheumatology 2021 19:166
  24. The transition of health care from Pediatric to Adult providers for adolescents and young adults with chronic disease is associated with poor outcomes. Despite the importance of this transition, over 80% of th...

    Authors: Rebecca S. Overbury, Kelly Huynh, John Bohnsack, Tracy Frech and Aimee Hersh
    Citation: Pediatric Rheumatology 2021 19:164
  25. Flares of juvenile idiopathic arthritis (JIA) have been described in the context of various infections. Flares of rheumatic diseases in adults have been described following infection with SARS-CoV-2 in several...

    Authors: Boris Hügle, Manuela Krumrey-Langkammerer and Johannes-Peter Haas
    Citation: Pediatric Rheumatology 2021 19:163
  26. This study aimed to assess the baseline characteristics and clinical outcomes of coronavirus disease 2019 (COVID-19) in pediatric patients with rheumatic and musculoskeletal diseases (RMD) and identify the ris...

    Authors: Daniel Clemente, Clara Udaondo, Jaime de Inocencio, Juan Carlos Nieto, Pilar Galán del Río, Antía García Fernández, Jaime Arroyo Palomo, Javier Bachiller-Corral, Juan Carlos Lopez Robledillo, Claudia Millán Longo, Leticia Leon, Lydia Abasolo and Alina Boteanu
    Citation: Pediatric Rheumatology 2021 19:162
  27. Mevalonate kinase deficiency (MKD) is a rare autoinflammatory condition caused by biallelic loss-of-function (LOF) mutations in mevalonate kinase (MVK) gene encoding the enzyme mevalonate kinase. Patients with MK...

    Authors: Ebun Omoyinmi, Dorota Rowczenio, Neil Sebire, Paul A. Brogan and Despina Eleftheriou
    Citation: Pediatric Rheumatology 2021 19:161
  28. Exercise has been suggested to prevent deterioration of health-related quality of life (HRQL) and overall health in pediatric rheumatologic diseases during the COVID-19 pandemic. Herein we describe the effects...

    Authors: Camilla Astley, Sofia Mendes Sieczkowska, Isabela Gouveia Marques, Bianca Pires Ihara, Livia Lindoso, Sofia Simão Martins Lavorato, Lucia Maria Arruda Campos, Rosa Maria Rodrigues Pereira, Adriana Maluf Elias, Nadia Emi Aikawa, Katia Kozu, Amanda Yuri Iraha, Tathiane Christine Franco, Hamilton Roschel, Ligia Bruni Queiroz, Guilherme Vanoni Polanczyk…
    Citation: Pediatric Rheumatology 2021 19:159
  29. Juvenile idiopathic arthritis (JIA) is the leading chronic rheumatic disease in childhood. To achieve adherence to therapy, in-depth understanding of disease and treatment options are important.

    Authors: Christiane Reiser, Nina A. Zeltner, Beatrix Rettenbacher, Petra Baumgaertner, Martina Huemer and Christian Huemer
    Citation: Pediatric Rheumatology 2021 19:158
  30. Kawasaki disease (KD) is a systemic vasculitis that predominantly affects medium-sized arteries. In addition to well-known coronary artery aneurysms (CAAs), peripheral systemic artery aneurysms (SAAs) have als...

    Authors: Chen Chu, Lan He, Yi-xiang Lin, Li-ping Xie and Fang Liu
    Citation: Pediatric Rheumatology 2021 19:157
  31. Children report that they do not participate in their healthcare as much as they want, despite having the lawful right to form their own views and the right to express those views freely in all matters affecti...

    Authors: Veronica Lundberg, Catharina Eriksson, Torbjörn Lind, Imelda Coyne and Anncristine Fjellman-Wiklund
    Citation: Pediatric Rheumatology 2021 19:156
  32. Intra-articular venous malformations (IAVM) are rare benign vascular anomalies that usually affect young patients and most common locate in the knee. The terminology of these lesions is still ill-defined, as t...

    Authors: Federico Diomeda, Maria Santaniello, Giulia Bracciolini, Angelo Ravelli and Adele Civino
    Citation: Pediatric Rheumatology 2021 19:153
  33. Juvenile Idiopathic Arthritis (JIA) requires complex care that generate elevated costs, which results in a high economic impact for the family. The aim of this systematic review was to collect and cluster the ...

    Authors: Fernando García-Rodríguez, Augusto Gamboa-Alonso, Sol Jiménez-Hernández, Lucero Ochoa-Alderete, Valeria Alejandra Barrientos-Martínez, Neri Alejandro Alvarez-Villalobos, Gabriela Andrea Luna-Ruíz, Ingris Peláez-Ballestas, Ana Victoria Villarreal-Treviño, Manuel Enrique de la O-Cavazos and Nadina Rubio-Pérez
    Citation: Pediatric Rheumatology 2021 19:152
  34. The aim of the study was to investigate the relationship between the severity of typical clinical symptoms, severity of histopathological lesions in kidney biopsies in IgA vasculitis nephritis (IgAVN) and to p...

    Authors: Małgorzata Mizerska-Wasiak, Agnieszka Turczyn, Karolina Cichoń-Kawa, Jadwiga Małdyk, Monika Miklaszewska, Dorota Drożdż, Beata Bieniaś, Przemysław Sikora, Magdalena Drożyńska-Duklas, Aleksandra Żurowska, Maria Szczepańska and Małgorzata Pańczyk-Tomaszewska
    Citation: Pediatric Rheumatology 2021 19:150
  35. Chronic anterior uveitis is a sight-threatening complication of juvenile idiopathic arthritis (JIA) and a primary contributor to long-term morbidity in people with JIA. Levels of knowledge about uveitis among ...

    Authors: Ashley M. Cooper, Elaine R. Flanagan, Tova Ronis, Baruch Goldberg, Ashley K. Sherman, Chelsey Smith and Gary N. Holland
    Citation: Pediatric Rheumatology 2021 19:149
  36. Intravenous immunoglobulin (IVIG) resistance prediction is one of the primary clinical issues and study hotspots in KD. This study aimed to prospectively investigate the value of albumin-bilirubin grade (ALBI)...

    Authors: Yu Yan, Lina Qiao, Yimin Hua, Shuran Shao, Nanjun Zhang, Mei Wu, Lei Liu, Kaiyu Zhou, Xiaoliang Liu and Chuan Wang
    Citation: Pediatric Rheumatology 2021 19:147
  37. Juvenile Idiopathic Inflammatory Myopathies (IIM) are a group of rare diseases that are heterogeneous in terms of pathology that can include proximal muscle weakness, associated skin changes and systemic invol...

    Authors: Meredyth G. Ll Wilkinson, Claire T. Deakin, Charalampia Papadopoulou, Despina Eleftheriou and Lucy R. Wedderburn
    Citation: Pediatric Rheumatology 2021 19:146
  38. The aetiology of juvenile idiopathic arthritis (JIA) is poorly understood. It has been shown that use of antibiotics is associated with JIA. However, whether the association is due to increased occurrence of i...

    Authors: Erik Kindgren and Johnny Ludvigsson
    Citation: Pediatric Rheumatology 2021 19:145
  39. Pleural effusion in systemic lupus erythematous (SLE) is a common symptom, and recent studies demonstrated that IL-6 has a pivotal role in its pathogenesis.

    Authors: Arianna De Matteis, Emanuela Sacco, Camilla Celani, Andrea Uva, Virginia Messia, Rebecca Nicolai, Manuela Pardeo, Fabrizio De Benedetti and Claudia Bracaglia
    Citation: Pediatric Rheumatology 2021 19:144
  40. Although canakinumab has demonstrated efficacy in multiple trials in patients with periodic fever syndromes (PFS), the evidence on initiation of canakinumab among PFS patients in real world setting is not well...

    Authors: Peter Hur, Kathleen G. Lomax, Raluca Ionescu-Ittu, Ameur M. Manceur, Jipan Xie, Jordan Cammarota, Raju Gautam, Navneet Sanghera, Nina Kim and Alexei A. Grom
    Citation: Pediatric Rheumatology 2021 19:143
  41. Autoinflammatory diseases (AID) are rare chronic conditions with high disease burden, affecting children and adults. Clinically and genetically confirmed, AID can be effectively treated with targeted cytokine ...

    Authors: Tatjana Welzel, Anna L. Wildermuth, Norbert Deschner, Susanne M. Benseler and Jasmin B. Kuemmerle-Deschner
    Citation: Pediatric Rheumatology 2021 19:142

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