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Table 1 Demographic data of the 90 children with JIA and 10 healthy children in the study

From: Blood brain barrier permeability and astrocyte-derived extracellular vesicles in children with juvenile idiopathic arthritis: a cross-sectional study

 

Children with JIA

N = 90

Healthy children

N = 10

 

Total group

No medical treatment

N = 42 (46,7)

Medical treatment

N = 48 (53.3)

 

Gender, number of girls (%)

68 (69)

  

6 (60)

Age at onset, years, Md (IQR)

5.7 (2.5–11.8)

   

Age at sampling, years, Md (IQR)

11.6 (6.7–15.1)*

  

8.4 (6.3–10.9)*

Disease duration at sampling

2.5 (0.9–5.8)

1.8 (0.2–5.1)

3.0 (1.6–6.7)

 

JADAS27, Md (IQR)

4.2 (1.8–8.8)

6.3 (2.7–11.9)**

3.6 (0.7–5.7)**

 

ILAR category, n (%)

Oligoarticular persistent

60 (66.7)

31

29

 

Polyarticular RF

15 (16.7)

5

10

 

Juvenile psoriatic arthritis

8 (8.9)

4

4

 

Oligoarticular extended

4 (4.4)

1

3

 

Enthesitis-related arthritis

2 (2.2)

1

1

 

Polyarticular RF+

1 (1.1)

0

1

 

Medical treatment, n (%)

MTX

  

27 (30)

 

Biological agent + MTX

  

11 (12.2)

 

Biological agent

  

10 (11.1)

 
  1. ILAR = International League of Associations for Rheumatology; RF = rheumatoid factor; MTX = metotrexat
  2. *Independent-Samples Mann-Whitney U test, p = 0.22; ** Independent-Samples Mann-Whitney U test, p = 0.009