Table 1 Classification of MISC and Methylprednisolone Dosing Based on Severity
Mild | Moderate | Severe (ICU care) | |
|---|---|---|---|
Respiratory support | None | None or minimal or significant | None or minimal or significant |
Cardiovascular support | None | None or minimal | Vaso actives or inotropes |
End organ injury | Minimal | Mild or isolated | Severe or multi-organ |
Initial dose (mg/kg/day) Maintenance daily dose | None or minimal | 10 mg/kg (max 1 g) x 1–3 days 2 mg/kg (max 60 mg) x 5 days | 20-30 mg/kg (max 1 g) x 1–3 days 2 mg/kg (max 60 mg) x 5 days |