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Table 1 Demographic features, disease onset, diagnosis, duration, and clinical features among adolescent girls with autoimmune rheumatic diseases

From: Ovarian dysfunction in adolescent girls with autoimmune rheumatic diseases

 

Adolescent girls with autoimmune rheumatic diseases

Total

(n = 52)

JSLE

(n = 21)

JIA

(n = 23)

JDM

(n = 8)

Median

(Minimum to Maximum)

Current age (years)

15 (13-17.5)

16 (14-17.5)

14 (13–17)

15 (14-16.5)

BMI

22 (17–32)

21.5 (18–30)

23.7 (17–32)

22 (18–23)

Age of disease onset (years) *#

12 (4–16)

13 (8–16)

11 (4-14.5)

9.5 (8–11)

Age of disease diagnosis (years) *

12.5 (5–16)

13 (7–16)

11 (5–15)

10 (10–13)

Duration of disease

(years) *#@

3 (0.2–10)

2 (0.2-5)

4 (1–10)

5.8 (4–7)

Clinical features N (%)

    

Fever

9 (17.3)

5 (23.8)

3 (13.0)

1 (12.5)

Weight loss

4 (7.7)

4 (19.0)

0 (0.0)

0 (0.0)

Fatigue

22 (42.3)

17 (81.0)

3(13.0)

2(25.0)

Lymphadenopathy

1 (1.9)

1 (4.8)

0 (0.0)

0 (0.0)

Mucocutaneous

15 (28.8)

12(57.1)

0 (0.0)

3(37.5)

Eye disease

0 (0.0)

0 (0.0)

0 (0.0)

0 (0.0)

Myositis

6 (11.5)

3(14.3)

1(4.3)

2(25.0)

Cardiopulmonary

5 (9.6)

4(19.0)

0 (0.0)

1(12.5)

GIT

1 (1.9)

0 (0.0)

1(4.3)

0 (0.0)

CNS

3 (5.8)

3(14.3)

0 (0.0)

0 (0.0)

Renal

6 (11.5)

6(28.6)

0 (0.0)

0 (0.0)

Arthritis/arthralgia

42 (80.8)

19 (90.5)

20 (87.0)

3(37.5)

  1. BMI: body mass index, corresponding symbols indicate significant difference between groups; *: Significant difference between JSLE and JIA, #: Significant difference between JSLE and JDM, @: Significant difference between JIA and JDM