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Table 4 Clinical and laboratory findings of normal and hyperprolactinemia SLE patients

From: Circulating prolactin level in Juvenile Systemic Lupus Erythematosus and its correlation with disease activity: a case control study

 

Normal prolactin

(n = 32)

Hyperprolactinemia

(n = 8)

P value

Age (years), mean ± SD

11.5 ± 2.2

11.5 ± 1.3

0.982

Sex, N (%)

Male

Female

5 (15.6%)

27 (84.4%)

1 (12.5%)

7 (87.5%)

0.825

Malar rash, N (%)

20 (62.5%)

6 (75%)

0.507

Discoid rash, N (%)

2 (6.3%)

0

0.468

Photosensitivity, N (%)

21 (65.6%)

4 (50%)

0.414

Oral ulcer, N (%)

13 (40.6%)

3 (37.5%)

0.827

Arthritis, N (%)

20 (62.5%)

7 (87.5%)

0.177

Serositis, N (%)

7 (21.9%)

1 (12.5%)

0.553

Renal disease, N (%)

17 (53.1%)

6 (75%)

0.263

Neurological disorders, N (%)

3 (9.4%)

4 (50%)

0.007*

Hematological disorders, N (%)

15 (46.9%)

4 (50%)

0.874

Immunological abnormalities, N (%)

27 (84.4%)

6 (87.5%)

0.533

Platelets (x103/ml), mean ± SD

286.5 ± 100.2

306.3 ± 107.3

0.457

ESR (cm/hr), mean ± SD

39.8 ± 25.6

27.5 ± 12.9

0.203

C3 (mg/dl), mean ± SD

22.4 ± 21.9

20.1 ± 25.7

0.509

C4 (mg/dl), mean ± SD

104.3 ± 67.6

69.8 ± 44.7

0.271

Positive ADNA, N (%)

22 (68.8%)

8 (100%)

0.068

Positive ANA, N (%)

31 (96.9%)

7 (87.5%)

0.277

SELDAI score, mean ± SD

10.9 ± 3.6

15.1 ± 3.2

0.004*

  1. *P value < 0.05
  2. BMI: body mass index, ESR: erythrocyte sedimentation rate, ADNA: anti-double stranded DNA, ANA: antinuclear antibodies