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Table 3 Comparison between mild, moderate, and severe SLE patients regarding demographic, anthropometric and laboratory findings

From: Circulating prolactin level in Juvenile Systemic Lupus Erythematosus and its correlation with disease activity: a case control study

Variables

Mild

(n = 7)

Moderate

(n = 18)

Severe

(N = 15)

p-value

Age (years), N (%)

11.8 ± 1.0

11.3 ± 2.4

11.5 ± 2.1

^0.838

Sex, N (%)

Male

2 (28.6%)

1 (5.6%)

3 (20.0%)

§ 0.243

Female

5 (71.4%)

17 (94.4%)

12 (80.0%)

Consanguinity, N (%)

1 (14.3%)

8 (44.4%)

5 (33.3%)

§ 0.463

Family history of SLE, N (%)

1 (14.3%)

4 (22.2%)

0 (0.0%)

§ 0.135

Weight (SDS), mean ± SD

-0.4 ± 0.6

-0.3 ± 1.0

-0.2 ± 1.3

^0.910

Height (SDS), mean ± SD

-0.3 ± 0.7

-0.2 ± 1.2

-0.2 ± 1.0

^0.965

BMI (SDS), mean ± SD

-0.2 ± 1.4

-0.3 ± 0.7

-0.2 ± 1.2

^0.941

Hypertension, N (%)

6 (85.7%)

13 (72.2%)

12 (80.0%)

§ 0.786

Puberty features, N (%)

2 (28.6%)

11 (61.1%)

9 (60.0%)

§ 0.371

Platelets (x103/mL), mean ± SD

286.1 ± 103.6

312.7 ± 102.2

265.8 ± 98.1

^0.419

ESR (mm/hr), mean ± SD

42.4 ± 17.2

33.9 ± 28.5

44.5 ± 29.2

^0.518

C3 (mg/dl), mean ± SD

58.1 ± 17.0

114.2 ± 65.6

95.6 ± 71.9

^0.149

C4 (mg/dl), mean ± SD

17.7 ± 18.1

20.4 ± 20.5

25.9 ± 26.6

^0.679

Positive ADNA, N (%)

4 (57.1%)

12 (66.7%)

14 (93.3%)

§ 0.073

Positive ANA, N (%)

6 (85.7%)

18 (100.0%)

14 (93.3%)

§ 0.296

Prolactin (µg/L), mean ± SD

14.0 ± 6.2

17.0 ± 5.3

19.3 ± 7.7

^0.212

  1. ^Independent t-test. #Chi square test, §Fisher’s Exact test
  2. BMI: body mass index, ESR: erythrocyte sedimentation rate, ADNA: anti-double stranded DNA, ANA: antinuclear antibodies, SDS: standard deviation scores