Table 1 Demographic, anthropometric and laboratory findings of SLE patients and controls
Variables | SLE cases (N = 40) | Control (N = 40) | P-value | ||
|---|---|---|---|---|---|
Age (years) | Mean ± SD | 11.5 ± 2.1 | 10.7 ± 1.9 | ^0.095 | |
Range | 6.4–15.3 | 7.8–15.5 | |||
Sex, N (%) | Male | 6 (15.0%) | 7 (17.5%) | #0.762 | |
Female | 34 (85.0%) | 33 (82.5%) | |||
Consanguinity, N (%) | 14 (35.0%) | 7 (17.5%) | #0.075 | ||
Family history of SLE, N (%) | 5 (12.5%) | 0 (0.0%) | § 0.055 | ||
Weight SDS, mean ± SD | -0.3 ± 1.1 | 0.3 ± 0.9 | ^0.012* | ||
Height SDS, mean ± SD | -0.2 ± 1.0 | 0.2 ± 1.0 | ^0.070 | ||
BMI SDS, mean ± SD | -0.2 ± 1.1 | 0.2 ± 0.9 | ^0.043* | ||
Hypertension, N (%) | 9 (22.0%) | 0 (0.0%) | § 0.002* | ||
Puberty features, N (%) | 22 (55.0%) | 32 (80.0%) | #0.017* | ||
Platelets (x103/ml), mean ± SD | 290.5 ± 100.6 | 302.9 ± 93.4 | ^0.567 | ||
ESR (mm/hr), mean ± SD | 39.4 ± 27.0 | 7.8 ± 2.8 | ^<0.001* | ||
C3 (mg/dl), mean ± SD | 97.4 ± 64.7 | 105.8 ± 26.2 | ^0.450 | ||
C4 (mg/dl), mean ± SD | 22.0 ± 22.3 | 24.3 ± 6.6 | ^0.538 | ||
Positive ADNA, N (%) | 30 (75.0%) | 0 (0.0%) | #<0.001* | ||
Positive ANA, N (%) | 38 (95.0%) | 0 (0.0%) | #<0.001* | ||
Prolactin (µg/L), mean ± SD | 17.3 ± 6.6 | 13.5 ± 5.3 | ^0.005* | ||
SLEDAI score, mean ± SD | 11.74 ± 3.9 |  |  | ||