Table 4 Characteristics of immunization side effects
Characteristics of immunization side effects | sJIA (N = 28) | % of total immunized sJIA patients (N = 81) | AOSD (N = 11) | % of total immunized AOSD patients (N = 18) | |
|---|---|---|---|---|---|
Type of reaction | |||||
Local symptoms at the injection site | 20 | 25% | 5 | 28% | |
Fever | 13 | 16% | 7 | 39% | |
Chills | 7 | 9% | 5 | 28% | |
Fatigue/ tiredness | 21 | 26% | 8 | 45% | |
Muscle pains | 11 | 14% | 6 | 33% | |
Headache | 13 | 16% | 6 | 33% | |
Nausea | 3 | 4% | 3 | 17% | |
Lymph node swelling | 5 | 6% | 3 | 17% | |
Rashes | 3 | 4% | 2 | 11% | |
Myocarditis | 0 | 0% | 0 | 0% | |
Disease flare | 1 | 1% | 2 | 11% | |
MIS-C/MIS-A | 0 | 0 | 1 | 6% | |
Other (please specify) | |||||
Atrial fibrillation | 0 | 0% | 1 | 6% | |
Pericarditis | 1 | 1% | 0 | 0% | |
Delayed flare | 1 | 1% | 0 | 0% | |
Flare of Crohn`s disease | 1 | 1% | 0 | 0% | |
Fever and URI symptoms | 1 | 1% | 0 | 0% | |
Food sensitivities | 0 | 0% | 1 | 6% | |
Coughing | 1 | 1% | 0 | 0% | |
Duration of reaction | |||||
≤2 days | 14 | 17% | 2 | 11% | |
3–7 days | 12 | 15% | 3 | 17% | |
≥ 8 days | 2 | 2% | 5 | 28% | |
Did not answer | 0 | 0% | 1 | 6% | |
Highest level of care required for patients who had side effects | |||||
No medical care required | 16 | 20% | 7 | 4% | |
Called physician | 7 | 9% | 2 | 11% | |
Visited a physician in clinic | 3 | 4% | 0 | 0% | |
Emergency department/urgent care | 2 | 2% | 0 | ||
Hospital admission | 0 | 0% | 1 | 6% | |
Intensive care unit admission | 0 | 0% | 1 | 6% |