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Table 1 Sociodemographic characteristics and clinical features of pediatric SS patients (n = 54)

From: A single-center study of clinical features of pediatric Sjögren’s syndrome

 

No.(n = 54)

pSS (n = 34)

sSS (n = 20)

P-value

Age at diagnosis (mean ± SD)

10.2 ± 2.6

10.0 ± 2.706

10.6 ± 2.4

0.416

Age at first sign/symptom (mean ± SD)

9.9 ± 2.6

9.7 ± 2.8

10.3 ± 2.3

0.383

Female: male ratio (%)

49:5(90.7)

32:2(94.1)

17:3(85.0)

0.347*

Dry mouth (%)

7(13.0)

2(5.9)

5(25.0)

0.087*

Dry eyes (%)

5(9.3)

3(8.8)

2(10.0)

1.000*

Fever (%)

29(53.7)

19(55.9)

10(50.0)

0.780*

Skin involvement (%)

25(46.3)

14(41.2)

11(55.0)

0.325

Arthralgia (%)

13(24.1)

4(11.8)

9(45.0)

0.009*

Arthritis (%)

7(13.0)

2(5.9)

5(25.0)

0.087*

Fatigue (%)

6(11.1)

4(11.8)

2(10.0)

1.000*

Glandular enlargement (%)

2(3.7)

1(2.9)

1(5.0)

1.000*

Peripheral lymphadenopathies (%)

21(38.9)

14(41.2%)

7(35.0)

0.653

Cytopenias (%)

16(29.6)

11(32.4)

5(25.0)

0.568

RTA (%)

5(9.3)

5(14.7)

0(0.0)

0.145*

Myalgias (%)

6(11.1)

5(14.7)

1(5.0)

0.395*

  1. SS Sjögren’s Syndrome, RTA Renal Tubular Acidosis
  2. P-value: pSS vs sSS
  3. Bold indicates P < 0.05
  4. *Fisher’s exact test