Table 3 Comparison of prophylactic treatment response between patients with extreme periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (ePFAPA) and non-extreme (nPFAPA)
Variables | ePFAPA (N = 47) | nPFAPA (N = 318) | P value | |
|---|---|---|---|---|
Colchicine | Patients treated, n (%) | 25 (53%) | 61 (19%) | < 0.001 |
Response (no/fewer flares), n (% of treated) | 16 (64%) | 43 (70%) | 0.56 | |
Cimetidine | Patients treated, n (%) | 3 (6%) | 6 (2%) | 0.13 |
Response (no/fewer flares), n (% of treated) | 0 (0%) | 2 (33%) | 0.50 | |
Montelukast | Patients treated, n (%) | 7 (15%) | 11 (3%) | < 0.001 |
Response (no/fewer flares), n (% of treated) | 2 (29%) | 4 (36%) | > 0.099 | |
Tonsillectomy | Patients treated, n (%) | 1 (2%) | 12 (4%) | > 0.99 |
Response (no/fewer flares), n (% of treated) | 1 (100%) | 3 (25%) | 0.31 |