From: Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
Characteristics | KFD (n = 57) | References |
---|---|---|
Demorgraphic Data | ||
Age, years | 9.08 (6.92–12.17) | |
Male to female ratio | 2:1 (38: 19) | |
Clinical manifestations | ||
Fever | 53 (92.98) | |
Lymphadenopathy | 54 (95.7) | |
Hepatomegaly | 20 (35.09) | |
Splenomegaly | 9 (15.79) | |
Skin rash | 15 (26.31) | |
Arthralgia/arthritis | 1 (1.75) | |
Gastrointestinal symptoms | 5 (8.77) | |
Respiratory symptoms | 7 (12.28) | |
Central nervous symptoms | 9 (15.79) | |
Laboratory variables | ||
WBC count (/μL) | 3530 (2540–4620) | 4300–11300 |
Hemoglobin (g/dL) | 11.5 (10.6–12.8) | 118–156 |
Neutrophil count (/μL) | 1575 (1230–2500) | 1600–7800 |
Lymophocyte count (/μL) | 1415 (1060–1820) | 1500–4600 |
Platelet count (× 103/μL) | 203 (174–259) | 167–453 |
AST (IU/L) | 37 (28–53) | 14–44 |
ALT (IU/L) | 21 (12–39) | 7–30 |
Albumin (g/L) | 38.6 (35.6–40.4) | 39–54 |
Ferritin (ng/mL) | 312.5 (147–710.8) | 14–200 |
Triglyceride (mg/dl) | 1.15 (0.96–1.5) | 0–1.7 |
Fibrinogen (mg/dL) | 3.78 (3.09–4.27) | 1.3–4.5 |
CRP (mg/L) | 5 (1.3–11.9) | 0–10 |
ESR (mm/h) | 40 (20–59) | 0–15 |
LDH (IU/mL) | 431 (335–647) | 192–321 |
Positive autobodies | 10 (17.5) |