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Table 1 Clinical and labortatory features of patients with KFD

From: Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease

Characteristics

KFD (n = 57)

References

Demorgraphic Data

 Age, years

9.08 (6.92–12.17)

 

 Male to female ratio

2:1 (38: 19)

 

Clinical manifestations

 Fever

53 (92.98)

 

 Lymphadenopathy

54 (95.7)

 

 Hepatomegaly

20 (35.09)

 

 Splenomegaly

9 (15.79)

 

 Skin rash

15 (26.31)

 

 Arthralgia/arthritis

1 (1.75)

 

 Gastrointestinal symptoms

5 (8.77)

 

 Respiratory symptoms

7 (12.28)

 

 Central nervous symptoms

9 (15.79)

 

Laboratory variables

 WBC count (/μL)

3530 (2540–4620)

4300–11300

 Hemoglobin (g/dL)

11.5 (10.6–12.8)

118–156

 Neutrophil count (/μL)

1575 (1230–2500)

1600–7800

 Lymophocyte count (/μL)

1415 (1060–1820)

1500–4600

 Platelet count (× 103/μL)

203 (174–259)

167–453

 AST (IU/L)

37 (28–53)

14–44

 ALT (IU/L)

21 (12–39)

7–30

 Albumin (g/L)

38.6 (35.6–40.4)

39–54

 Ferritin (ng/mL)

312.5 (147–710.8)

14–200

 Triglyceride (mg/dl)

1.15 (0.96–1.5)

0–1.7

 Fibrinogen (mg/dL)

3.78 (3.09–4.27)

1.3–4.5

 CRP (mg/L)

5 (1.3–11.9)

0–10

 ESR (mm/h)

40 (20–59)

0–15

 LDH (IU/mL)

431 (335–647)

192–321

 Positive autobodies

10 (17.5)

 
  1. Data expressed as median (interquartile range) or n (%)
  2. KFD Kikuchi-Fujimoto disease, WBC white blood cell, ESR erythrocyte sedimentation rate, CRP C-reactive protein, ALT alanine aminotransferase, LDH lactate dehydrogenase, AST aspartate aminotransferase, ANA anti-nuclear antibodies