Fig. 2
From: Treat-to-target strategies for the management of familial Mediterranean Fever in children
Consensus treat-to-target approach in the treatment of familial Mediterranean fever. Following diagnostic evaluation patients with clear or probable FMF should be treated according to the designated treatment path. Evaluation of disease activity is to be performed every 3–6 months according to the composite score proposed in Fig. 1. For dosing of IL-1 antagonists in children, we refer to the Summary of Product Characteristics of the chosen agent in line with the patient’s medical need. Legend: GC, glucocorticoid; MTX, methotrexate; NSAID, non-steroidal anti-inflammatory drug; PGA, Patient/Physician Global Assessment