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Table 2 Geometric mean concentrations and 95% confidence intervals of MenACWY PS-specific IgG concentrations (µg/ml) during follow-up

From: Meningococcal ACWY conjugate vaccine immunogenicity in adolescents with primary or secondary immune deficiencies, a prospective observational cohort study

Months

Serogroup

Study participants

Healthy controls

P

0

 

n = 26

n = 75

 
 

MenA

0.1; 0.1–0.21

0.6; 0.5–0.81

< 0.01*

 

MenC

0.5; 0.2–1.0

0.3; 0.3–0.5

0.36

 

MenW

0.0; 0.0–0.1

0.2; 0.1–0.3

< 0.01*

 

MenY

0.0; 0.0–0.1

0.1; 0.1–0.1

0.23

3–6

 

n = 45

n = 0

 
 

MenA

5.3; 3.3–8.7

-

-

 

MenC

38.5; 22.5–65.8

-

-

 

MenW

1.5; 0.9–2.5

-

-

 

MenY

3.0; 1.7–5.5

-

-

12

 

n = 47

n = 75

 
 

MenA

2.5; 1.6–3.7

8.2; 6.5–10.4

< 0.01*

 

MenC

14.6; 9.4–22.51

16.9; 14.0–20.4

0.53

 

MenW

1.1; 0.7–1.8

4.5; 3.3–6.3

< 0.01*

 

MenY

2.1; 1.3–3.7

2.5; 1.7–3.8

0.60

24

 

n = 39

n = 0

 
 

MenA

1.2; 0.8–2.0

-

-

 

MenC

5.6; 3.1–10.2

-

-

 

MenW

0.4; 0.3–0.7

-

-

 

MenY

1.0; 0.6–1.7

-

-

  1. *P < 0.05
  2. 1one missing observation