Table 3 Clinical and laboratory characteristics in patients with leukemic arthritis vs JIA
From: Differences between leukemic arthritis and juvenile idiopathic arthritis
Variable | Leukemic arthritis (n = 14) | JIA (N = 62) | p value | RR (IC 95%) |
|---|---|---|---|---|
Age (years) | 8.1 (3–14) | 10.3 (2–15) | 0.084 | |
Female gender | 50% | 79% | *0.026 | |
Time of symptoms onset (months) | 4.29 (1–12) | 9.15 (1–72) | *0.017 | |
Pain intensitiy VAS (0–10) | 10 | 7 (2–10) | *0.0001 | |
Night time pain | 79% | 10% | *0.0001 | 12.7 (4–40) |
Pain relief with analgesics | 0% | 74% | *0.0001 | 0.53(0.38–0.74) |
Fever | 64% | 6.5% | *0.0001 | 8.7 (3.4–21.7) |
Nocturnal diaphoresis | 50% | 0% | *0.0001 | 9.8 (4.8–19.8) |
Weightloss | 86% | 19% | *0.0001 | 13 (3.1–53.6) |
Lymphadenopathies | 86% | 3% | *0.0001 | 26 (6.6–105) |
Hepatosplenomegaly | 57% | 3% | *0.0001 | 8.8 (3.8–20) |
Rheumatoid factor | 0% | 25% | 0.011 | |
Anemia (hb < 11 g/dL) | 42% | 8% | *0.001 | 4.4 (1.9–10.3) |
Hemoglobin g/dL | 11.5 (8.3–14.7) | 13 (8.4–16.4) | 0.009 | |
Leukopenia (< 4000 mm3) | 71% | 2% | *0.0001 | 14.7 (5.6–38) |
Leukocytes mm3 | 3508 (1610–5560) | 9111 (4450–24,630) | *0.0001 | |
Neutropenia (< 1500 mm3) | 92% | 0% | *0.0001 | 63 (9–440) |
Neutrophils mm3 | 695 (0–1820) | 5413 (2070–22,130) | *0.0001 | |
Lymphocytes mm3 | 2488 (460–4230) | 2787 (1320–9280) | 0.583 | |
Thrombocytopenia (< 150 × 103/mm3) | 43% | 0% | *0.0001 | 8.7 (4.5–16.7) |
Platelets × 103/mm3 | 191 (53–406) | 378 (196–759) | *0.0001 | |
ESR mm/hr | 34 (20–67) | 27.7 (2–66) | 0.302 | |
CRP | 39 (5–100) | 25 (0–226) | 0.247 |