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Fig. 4 | Pediatric Rheumatology

Fig. 4

From: MicroRNA-27a-3p enhances the inflammatory phenotype of Juvenile Idiopathic Arthritis fibroblast-like synoviocytes

Fig. 4

Transfection with miR-27a-3p enhances FLS proliferation. FLS were transfected with either miR-27a-3p mimic or miR-NC, then stimulated with pooled JIA synovial fluid (SF) or the cytokine combination IL-1β, IL-6 and TNF (cytokines). Unstimulated FLS were used as a no treatment control. Cell proliferation was determined by 3H-thymidine incorporation assay. Graph shows 3H incorporation in counts per minute in individual paired FLS cultures (n = 7). *p < 0.05

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Pediatric Rheumatology

ISSN: 1546-0096