Table 1 Main characteristics of the studies included in this analysis
Study (year) | Country | Study design | Period(y) | Participants (pregnancies) | Maternal outcomes | Fetal outcomes | NOS score |
|---|---|---|---|---|---|---|---|
Ruffatti 2016 [8] | Italy | retrospective | 2009–2014 | 12(12) | type of delivery, pregnancy complications, gestational period (weeks), preterm labor | 5 min APGAR score, neonatal complications, birth weight, cardiac complications, NICU admission, small for gestational age | ****** |
Zuppa 2008 [9] | Italy | retrospective | 2004–2005 | 10(10) | type of delivery, gestational period (weeks), preterm labor | live birth, birth weight, hematologic manifestation, echoencephalographic abnormalities, liver manifestations | ****** |
Morel 2017 [10] | France | – | 2000–2014 | 174(187) | gestational period (weeks), preterm labor | fetal death /perinatal death, birth weight, DCM, EFE, hydrops, Pericardial effusion, congenital heart disease, pacemaker implantation | ***** |
Cimaz 2003 [11] | Canada | prospective | 1987–2000 | 112(128) | preterm labor | live birth, type of block, skin manifestations, hematologic manifestation, liver manifestations, prolonged QT interval, CHB recurrence, hematological and hepatic manifestations | ****** |
Boros 2007 [12] | Canada | – | 1999–2004 | 75(87) | – | type of block, hydrocephalus, cutaneous involvement, hematologic and/or liver enzyme abnormalities, hematological and hepatic manifestations | ****** |
Miniaoui 2022 [13] | France | – | 2000–2019 | 215(215) | terminations of pregnancy, disease-free survival probability at 5 years and 10 years, the probability of developing SLE/SS, the estimated median time to progression | fetal death /perinatal death, live birth | ****** |
Gladman 2002 [14] | Canada | prospective | 1988–1997 | 105(118) | spontaneous abortion | intrauterine deaths, DCM, type of block, peripheral pulmonary artery stenosis, CHB recurrence | ****** |
Pisoni 2010 [15] | Italy | prospective | 2004–2008 | 22(24) | terminations of pregnancy | type of block, cutaneous involvement, CHB recurrence | ****** |
Skog 2015 [16] | Sweden | prospective | 2000–2013 | 155(212) | type of delivery, preterm labor, preeclampsia | fetal death /perinatal death, type of block, CHB recurrence, neonatal complications | ***** |
Jaeggi 2010 [7] | Canada | prospective | 2000–2008 | 164(186) | termination of pregnancy | intrauterine death, type of block, endocardial fibroelastosis, hydrops, pericardial effusion, CHB recurrence, hematological and hepatic manifestations | ****** |
Sonesson 2004 [17] | Sweden | – | 1999–2003 | 24(24) | preterm labor | type of block | ******** |
Kan 2017 [18] | Canada | retrospective | 2009–2014 | 189(195) | maternal eclampsia | intrauterine death, pacemaker implantation, type of block, endocardial fibroelastosis, pericardial effusion, congenital heart disease, CHB recurrence | ****** |
Bergman 2012 [19] | Sweden | crosssectional follow-up | 1999–2007 | 48(57) | – | type of block | ***** |
Gerosa 2007 [20] | Italy | prospective | 2000–2004 | 60(60) | spontaneous abortion, preterm labor | pacemaker implantation,1 min APGAR score, type of block | ******** |
Motta 2007 [21] | Italy | prospective | 1999–2005 | 43(51) | – | type of block | ****** |
Chalumeau 2004 [22] | France | – | 1991–2002 | 106(167) | spontaneous abortion, terminations of pregnancy, preterm labor | IUGR，fetal death /perinatal death，live birth，type of block, congenital defects | ******** |
Brucato 2002 [23] | Italy | prospective | – | 100(126) | type of delivery, ectopic pregnancy, spontaneous abortion, preeclampsia, pregnancy complications, preterm labor | live birth, small for gestational age, type of block, IUGR | ******** |
Briassouli 2013 [24] | USA | retrospective | – | 61(61) | type of delivery | – | ***** |