MTX group n = 97 | non-MTX group n = 83 | p value | |
---|---|---|---|
Female (%) | 62 (64) | 47 (57) | 0.32 |
Age (years), mean (SD) | 7.5 (3.6) | 8.6 (3.8) | 0.037 |
Height (cm), mean (SD) | 122 (23) | 128 (239) | 0.11 |
Weight (kg), mean (SD) | 26.5 (13.0) | 28.6 (13.7) | 0.27 |
BMI, kg/ m2 | 16.6 (2.8) | 16.5 (2.5) | 0.77 |
BSA (m2), mean (SD) | 0.94 (0.31) | 1.00 (0.33) | 0.17 |
Disease duration (years), mean (SD) | 2.3 (2.4) | 3.2 (2.8) | 0.019 |
Diagnosis | 0.74 | ||
Oligoarthritis, persistent | 17 (18) | 18 (22) | |
Oligoarthritis, extended | 15 (15) | 14 (17) | |
Polyarthritis, RF-negative | 57 (49) | 40 (48) | |
Polyarthritis, RF-positive | 2 (2) | 1 (1) | |
Enthesitis related arthritis | 4 (4) | 7 (8) | |
Psoriatic arthritis | 1 (1) | 2 (2) | |
Undifferentiated arthritis | 1 (1) | 1 (1) | |
Uveitis, n (%) | 9 (9) | 2 (2) | 0.066 |
Inflammatory bowel disease, n (%) | 1 (1) | 1(1) | 0.99 |
Previous bDMARD, n (%) | 10 (10) | 15 (18) | 0.13 |
Etanercept | 7 | 10 | |
Adalimumab | 3 | 4 | |
Infliximab | 2 | 4 | |
Tocilizumab | 0 | 2 | |
Concomitant treatment n (%) | |||
Other sDMARDs | 6 (6) | 32 (39) | < 0.001 |
Prednisolone | 4 (4) | 7(8) | 0.23 |
ESR (mm/h), mean (SD) | 13.2 (14.0) | 12.1 (12.1) | 0.61 |
CRP (mg/l), mean (SD) | 4.9 (12.6) | 5.9 (13.5) | 0.63 |
JADAS10, mean (SD) | 10.0 (5.6) | 9.7 (5.8) | 0.56 |
PaGA, mean (SD) | 3.3 (2.6) | 2.6 (2.2) | 0.10 |
PhGA, mean (SD) | 3.1 (1.8) | 2.7 (1.9) | 0.14 |
HLA-B27 positive, n (%) | 27 (28) | 25 (30) | 0.58 |
ANA, n (%) | 31 (32) | 23 (28) | 0.54 |
Erosions, n (%) | 21 (22) | 16 (19) | 0.60 |