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Table 1 Values of JADAS, ESR and CRP over the study period. Values are mean and range and statistical significance for differences in repeated measures by Friedman test was considered when < 0.05

From: Strategic use of levofolinic acid for methotrexate-induced side effects in juvenile idiopathic arthritis: a prospective observational study

 

T0

T1

T2

T3

T4

p

JADAS

Mean (range)

3.77

(0.0–14.0)

2.7

(0.0–8.0)

1.94

(0.0–8.0)

1.36

(0.0–5.0)

1.63

(0.0–5.0)

0.006

ESR (mm/h)

Mean (range)

7.29

(2.0–20.0)

8.5

(2.0–40.0)

4.86

(2.0–22.0)

6.93

(2.0–39.0)

5.93

(2.0–28.0)

n.s

CRP (mg/L)

Mean (range)

3.12

(1.0–11.0)

3.84

(0.5–28.0)

1.64

(0.5–3.0)

2.41

(0.5–12.0)

1.45

(0.5–5.0)

0.008