Skip to main content

Table 1 Summary of study type and patient characteristics in SLR-identified publications (n = 87) by TNFi treatment

From: Efficacy and safety of TNF inhibitors in the treatment of juvenile idiopathic arthritis: a systematic literature review

 

Adalimumab

Etanercept

Golimumab

Infliximab

Study type, n

 Total

26

67

7

14

 Observational

22

55

5

12

 RCT

3

8

1

1

 nRCT

1

4

1

1

JIA category, n

 Multiple

9

26

3

5

 PA

3

11

2

1

 sJIA

1

5

0

0

 nsJIA

1

3

0

0

 ERA

1

7

0

0

Age at treatment start, years

 Mean

3.0–17.5

3.1–16.2

11.1–13.6

10.6–21.8

 Median

4.9–13.9

10.0–21.0

13.0*

11.9*

Follow-up duration

 Mean, years

3.58–3.96

0.5–6.8

1.0*

0

 Median, months

51.0–53.7

12.0–35.6

0

51.0–53.7

 Range, months

3–120

3–216

7–40

12–120

 Person-years

14–1,855

3–6,726

3.5–326

26–591

  1. *Data are from a single study
  2. ERA  Enthesitis-related arthritis, JIA   Juvenile idiopathic arthritis, nRCT   Nonrandomized controlled trial, nsJIA   Nonsystemic juvenile idiopathic arthritis, PA   Polyarticular arthritis, RCT   Randomized controlled trial, SLR   Systematic literate review, sJIA   Systemic juvenile idiopathic arthritis, TNFi   Tumor necrosis factor inhibitor