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Table 1 Clinical characteristics and management of KFD patients

From: Macrophage activation syndrome in children with Kikuchi-Fujimoto disease

 

Without MAS (n = 43)

With MAS (n = 15)

p-value

Demorgraphic Data

 Age, years

8.5 (6.8–11.8)

10.58 (7.2–12.9)

0.86

 Male to female ratio

1.69 (27:16)

2.75 (11:4)

0.54

 Follow-up (years)

3.58 (2.33–5.25)

4.33 (3.0–5.5)

0.18

Clinical manifestations

 Fever

39 (90.7)

15 (100)

0.34

 Hepatomegaly

14 (32.6)

5 (33.3)

 > 0.9999

 Splenomegaly

7 (16.3)

1 (6.7)

0.44

 Skin rash

1 (2.3)

4 (26.7)

0.01

 Arthralgia/arthritis

1 (2.3)

1 (6.7)

 > 0.9999

 Gastrointestinal symptoms

4 (9.3)

1 (6.7)

 > 0.9999

 Respiratory symptoms

4 (9.3)

3 (20.0)

0.36

 Central nervous symptoms

7 (16.3)

2 (13.3)

 > 0.9999

  1. Data expressed as median (interquartile range) or n (%). Variables such as age and follow-up were acessed by Unpaired Welch’s t-test. Others were compared by Man-Whitney U test. KFD Kikuchi-Fujimoto disease, MAS macrophage activation syndrome