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Fig. 4 | Pediatric Rheumatology

Fig. 4

From: Profiling the peripheral immune response to ex vivo TNF stimulation in untreated juvenile idiopathic arthritis using single cell RNA sequencing

Fig. 4

Dot plots showing variability of expression of IL-18 pathway genes. Each dot shows the average expression (log2 counts per 100,000 of positive cells) of the indicated gene (columns), with the size of the dot scaled to the proportion of cells positive for the gene. Darker red is higher expression. Genes are clustered from top to bottom in sets of NK cells, T-cells, B-cells, and Myeloid cells, with Null above TNF-stimulated in each pair. Even though the IL-18 pathway is engaged by stimulus in each cell type, different subsets of genes are responsible for the response

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Pediatric Rheumatology

ISSN: 1546-0096