Table 2 Clinical and laboratory characteristics of 66 patients with juvenile idiopathic arthritis (JIA), collected at two different study visits, at a higher and a lower disease activity state

Disease activity

Higher

Lower

p-value*

JADAS27 Md (IQR)

11.4 (6.8 – 17.1)

1.3 (0.1 – 2.8)^b

< 0.001

Medical treatment

 No medical treatment

61

15

-

 Methotrexate (MTX)

3

27

-

 MTX + bDMARD

1

12

-

 bDMARD

10

-

 MTX + bDMARD + prednisolone

1

-

 bDMARD and prednisolone

1

-

 prednisolone

1

-

Liver related proteins, Md (IQR)

p-value*

Haptoglobin, g/L

1.5 (0.8 – 2.6)

0.7 (0.4 – 1.0)

< 0.001

Albumin, g/L

41 (37 – 43)

44 (42 – 46)

< 0.001

CRP, mg/L

2.2 (0.5 – 14.0)

0.4 (0.2 – 1.2)

< 0.001

Serum amyloid A, mg/L, (n=27)

1.7 (0.3 – 10.5)

0.4 (0.3 – 0.9)

< 0.001

Total protein, g/L^a

74 (69 – 79)

77 (72 – 82)

< 0.05