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Table 1 Demographic and clinic data for all patients requiring treatment with intraarticular steroids (IAS) or systemic treatment

From: Intraarticular steroids as DMARD-sparing agents for juvenile idiopathic arthritis flares: Analysis of the Childhood Arthritis and Rheumatology Research Alliance Registry

Category

 

Total n (% or mean)

IAS n (%)

Systemic Treatment n (%)

p-value

 

All

185 (100%)

46 (25%)

139 (75%)

 

Sex

Male

46 (25%)

12 (26%)

34 (24%)

0.82

 

Female

139 (75%)

34 (74%)

105 (76%)

 

Age at Diagnosis (years)

 

7.3 (4.7)

7.1 (4.7)

7.4 (4.7)

0.72

Race*

White

160 (86%)

42 (91%)

118 (85%)

0.78

 

Black, African American, African, or Afro-Caribbean

5 (3%)

2 (4%)

3 (2%)

 

Hispanic, Latino, or Spanish origin

14 (8%)

3 (7%)

11 (8%)

 

Asian

6 (3%)

0 (0%)

6 (4%)

 

Middle Eastern/North African

1 (1%)

1 (2%)

0 (0%)

 

Native American, American Indian or Alaskan Native

1 (1%)

0 (0%)

1 (1%)

 

Native Hawaiian or Other Pacific Islander

1 (1%)

0 (0%)

1 (1%)

JIA subtype

Oligoarticular

77 (42%)

27 (59%)

50 (36%)

0.07**

 

Polyarticular

78 (42%)

14 (30%)

64 (46%)

 
 

Psoriatic

15 (8%)

4 (9%)

11 (8%)

 
 

ERA

12 (6%)

1 (2%)

11 (8%)

 
 

Undifferentiated

3 (2%)

0 (0%)

3 (2%)

 

ANA

Negative

98 (53%)

21 (46%)

77 (55%)

0.25

 

Positive

87 (47%)

25 (54%)

62 (45%)

 

RF

Negative

178 (96%)

46 (100%)

132 (95%)

0.2

 

Positive

7 (4%)

0 (0%)

7 (5%)

 

CCP

Negative

178 (96%)

45 (98%)

133 (96%)

0.68

 

Positive

7 (4%)

1 (2%)

6 (4%)

 

B27

Negative

171 (92%)

42 (91%)

129 (93%)

0.75

 

Positive

14 (8%)

4 (9%)

10 (7%)

 

Uveitis

No

159 (86%)

37 (80%)

122 (88%)

0.21

 

Yes

26 (14%)

9 (20%)

17 (12%)

 

Methotrexate

No

8 (4%)

3 (7%)

5 (4%)

0.41

 

Yes

177 (96%)

43 (93%)

134 (96%)

 

Biologic

No

49 (26%)

22 (48%)

27 (19%)

< 0.001

 

Yes

136 (74%)

24 (52%)

112 (81%)

 
  1. *Patients were allowed to identify as more than 1 race thus the sum of percents is greater than 100. **p=0.0157 when psoriatic, enthesitis-related arthritis and undifferentiated arthritis were excluded