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Table 2 Prevalence rates of ADs in parents of included JIA patients (n = 17,346)

From: Prevalence of familial autoimmune diseases in juvenile idiopathic arthritis: results from the international Pharmachild registry

Disease

Frequency

Prevalence per 100,000 (95% Poisson CI)

Global prevalence per 100,000

Psoriasis

369

2127 (1916 – 2356)

140–1990 [16]

Autoimmune thyroid disease

275

1585 (1404 – 1784)

GD:0–2000 [17] HT: 0–7000 [17]

Rheumatoid arthritis

141

813 (684–959)

300–700 [18]

Ankylosing spondylitis

136

784 (658–927)

20–350 [19]

Inflammatory bowel disease

68

392(304–497)

UC: 2–505 [20]

CD: 1–322 [20]

Juvenile idiopathic arthritis

51

294 (219–387)

21 [21]

Asthma

48

277 (204–367)

4300 [22]

Insulin-dependent diabetes mellitus

38

219 (155–301)

39–96 [23]

Systemic lupus erythematosus

31

179 (121–254)

0–241 [24]

Vitiligo

29

167 (112–240)

100–1200 [25]

Other autoimmune arthritis

28

161 (107–233)

-a

Celiac disease

27

156 (103–226)

400–800 [26]

Other autoimmune disease

25

144 (93–213)

-a

Uveitis

17

98 (57–157)

9–730 [27]

Multiple sclerosis

16

92 (53–150)

2–164.6 [28]

Sarcoidosis

15

87 (48–143)

2–160 [29]

Reactive arthritis

12

69 (36–121)

0–200 [19]

Other connective tissue disease

11

63 (32–114)

-a

Sjögren’s syndrome

10

58 (28–106)

61 [30]

Rheumatic fever

8

46 (20–91)

-b

Vasculitides

5

29 (9–68)

-a

Still’s disease

4

23 (6–59)

1–6.8 [31]

Familial Mediterranean fever

2

12 (1–42)

-c

  1. AD Autoimmune disease, CD Crohn’s disease, CI Confidence interval, GD Graves’ disease, HT Hashimoto’s thyroiditis, UC Ulcerative colitis
  2. aheterogeneous group of diseases, bnot a chronic disease, cmainly affects ethnic groups from the eastern Mediterranean region