Table 2 Distribution of radiologically active bone lesions at baseline and after one year of pamidronate therapy

Head

1 (1)

1 (2)

1 (6)

1 (6)

-

 Mandibula

1 (1)

1 (2)

1 (6)

1 (6)

Chest

6 (5)

5 (8)

6 (33)

5 (28)

0.5

 Clavicula

3 (3)

3 (5)

3 (17)

3 (17)

 Sternum

1 (1)

0

1 (6)

0

 Scapula*

2 (2)

2 (3)

2 (11)

2 (11)

Upper extremities

4 (4)

0

3 (17)

0

0.13

 Proximal humerus

1 (1)

0

1 (6)

0

 Distal humerus

1 (1)

0

1 (6)

0

 Proximal radius/ulna

1 (1)

0

1 (6)

0

 Distal radius/ulna

1 (1)

0

1 (6)

0

Pelvis

21 (19)

13 (21)

10 (56)

8 (44)

0.06

 Pelvis-ileum*

11 (10)

5 (8)

8 (44)

4 (22)

 Pelvis-pubis

1 (1)

1 (2)

1 (6)

1 (6)

 Pelvis-ischium

2 (2)

3 (5)

2 (11)

3 (17)

 Pelvis-sacrum

7 (6)

4 (7)

6 (33)

4 (22)

Distal extremities

49 (45)

26 (43)

16 (89)

9 (50)

 < 0.01

 Proximal femur*

10 (9)

6 (10)

7 (39)

3 (17)

 Distal femur

8 (7)

3 (5)

6 (33)

2 (11)

 Proximal tibia*

11 (10)

4 (7)

9 (50)

3 (17)

 Distal tibia*

15 (14)

9 (15)

9 (50)

6 (33)

 Proximal fibula

0

0

0

0

 Distal fibula

5 (4)

4 (7)

4 (22)

3 (17)

Feet

13 (12)

10 (17)

8 (44)

6 (33)

0.55

 Foot-calcaneus *

5 (4)

6 (10)

4 (22)

4 (22)

 Foot- talus*

3 (3)

2 (3)

3 (17)

2 (11)

 Foot-middle

5 (4)

2 (3)

4 (22)

1 (6)

Spine

16 (15)

6 (10)

6 (33)

3 (17)

 < 0.01

 Cervical vertebra

0

0

0

0

 Thoracic vertebra*

15 (14)

2 (3)

5 (28)

2 (11)

 Lumbar vertebra*

1 (1)

4 (7)

1 (6)

1 (6)

Total

110 (100)

61 (100)

-

-