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Fig. 3 | Pediatric Rheumatology

Fig. 3

From: Standardized reporting and quantification of whole-body MRI findings in children with chronic non-bacterial osteomyelitis treated with pamidronate

Fig. 3

Changes in radiological disease activity following one year of pamidronate treatment. Radiological response to pamidronate treatment in children diagnosed with severe CNO (n = 18). WBMRI was assessed prior to pamidronate treatment and following one year of treatment. A Changes in the modified radiological index for non-bacterial osteitis (mRINBO), p = 0.05 B Changes in total number of radiologically active lesions (RAL) per patient, p = 0.02 C Changes in the size of the largest RAL for each patient (RALmax) p < 0.01. D Changes in the number of RAL for each patient in the spine, p < 0.01. Comparison between baseline and year one was made using Wilcoxon signed rank test

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