Fig. 2From: Standardized reporting and quantification of whole-body MRI findings in children with chronic non-bacterial osteomyelitis treated with pamidronateWhole-body MRI following one year of pamidronate treatment. Representative MRI images of a 7-year-old girl diagnosed with chronic non-bacterial osteomyelitis (CNO) and imaging following one year of pamidronate treatment. AÂ Pre-pamidronate whole-body magnetic resonance imaging (WBMRI) short tau inversion recovery (STIR), coronal image shows multiple areas of bone marrow edema as signs of radiologically active lesions (RAL) (white thin arrows). BÂ Post-pamidronate coronal WBMRI STIR image showed resolution of RAL in the left acetabulum and regression of RAL in the right femur. Assessment of RAL in the distal femur and proximal tibia is challenged by bisphosphonate bands (dotted arrows) CÂ Pre-pamidronate and DÂ post-pamidronate coronal MRI STIR images of the clavicles showing post-treatment regression of bone marrow edema and surrounding soft tissue edemaBack to article page