Skip to main content

Table 3 Disease and health-related outcomes and medications used at the study visit

From: Transitioning patients with juvenile idiopathic arthritis to adult care: the Nordic experience

 

Directly transferred (D)

(n = 163)

Later referred (L)

(n = 50)

Not transferred (N)

(n = 195)

P-value

[multiple comparison] *

HAQ, mean (SD)

0.32 (0.52)

0.13 (0.32)

0.05 (0.27)

< 0.001 [D/L, D/N]

Patients with active joints, n (%)

45 (28)

9 (18)

8 (4)

< 0.001[D/L, D/N, L/N]

Number of cumulative active joints, median (IQR)

15.2 (11.8)

8.8 (8.2)

5.3 (5.6)

< 0.001 [D/L, D/N, L/N]

DAS28, mean (SD)

2.21 (1.31)

1.79 (1.00)

1.29 (0.75)

< 0.001 [D/L, D/N, L/N]

VAS 0–100 mean (SD)

 Pain

27 (26)

21 (26)

9 (16)

< 0.001 [D/N, LN]

 Physicians’ global

13 (20)

8 (16)

2 (8)

< 0.001 [D/N, L/N]

 Patients’ global

27 (29)

18 (23)

8 (16)

< 0.001 [D/L, D/N, L/N]

 Fatigue

43 (28)

36 (27)

35 (27)

0.045 [D/N]

JADI-A, n (%)

   

< 0.001 [D/L, D/N, L/N]

 0

115 (71)

43 (86)

187 (96)

 

 1

19 (12)

4 (8)

5 (3)

 

 2–4

21 (13)

2 (4)

3 (2)

 

  ≥ 5

8 (5)

1 (2)

0 (0)

 

CAM, n (%)

21 (13)

6 (12)

22 (11)

0.90

Medication, n (%)

95 (58)

14 (28)

0 (0)

< 0.001 [D/N, L/N]

 Synthetic DMARDs, n

62

11

0

 

 Biologic DMARDs, n

65

4

0

 

 Systemic steroids, n

8

2

0

 

SF-36, mean (SD):

 Physical component score

47.8 (10.8)

49.5 (10.5)

55.5 (6.5)

< 0.001 [D/N, L/N]

 Mental component score

47.7 (12.7)

51.2 (8.6)

49.8 (11.0)

0.12

Socioeconomics n (%)

   

0.089

 Student

71 (45)

17 (35)

85 (44)

 

 Working

68 (43)

28 (58)

98 (51)

 

 Unemployed

5 (3)

2 (4)

5 (3)

 

 Disability pension

14 (9)

1 (2)

5 (3)

 

  JIA-related

6 (4)

0 (0)

0 (0)

 

  Other reasons

8 (5)

1 (2)

5 (3)

 

Physical exercise

   

0.68

  < once a week

24 (17)

5 (13)

19 (12)

 

 1–3 times a week

89 (61)

26 (67)

102 (62)

 

 4–7 times a week

32 (22)

8 (21)

43 (26)

 

Physiotherapy, ongoing, n (%)

17 (11)

4 (10)

6 (4)

0.030 [D/N]

Inactive diseasea off medication between 8 and 18 year study visits, n (%)

10 (6)

8 (16)

146 (75)

< 0.001 [D/L, D/N, L/N]

JIA-U ever, n (%)

41 (25)

15 (30)

18 (9)

< 0.001 [D/N, L/N]

  1. D Directly transferred, L Later referred, N Not transferred
  2. * Hommel’s multiple comparison procedure was used to correct significance levels for post hoc testing (p < 0.05)
  3. aAccording to the Wallace preliminary criteria [16]
  4. SD Standard deviation, IQR Interquartile Range, HAQ Health Assessment Questionnaire, DAS28 Disease activity score, VAS Visual Analogue Scale, JADI-A The Juvenile Arthritis Damage Index assessment of articular damage, JIA-U Juvenile idiopathic arthritis-related uveitis, CAM Complementary and alternative medicine, DMARDs Disease-modifying anti-rheumatic drugs, SF-36 36-item Short Form Health Survey, JIA Juvenile idiopathic arthritis