Table 3 Atypical symptoms in PFAPA with age of onset < 5 vs ≥ 5 years
All PFAPA (n = 336) | Onset < 5 years (n = 291) | Onset ≥ 5 years (n = 45) | |
|---|---|---|---|
Any atypical symptom | 49/336 (14.6%) | 39/291 (13.4%) | 10/45 (22.2%) |
Skin rash | 16/336 (4.8%) | 14/291 (4.8%) | 2/45 (4.4%) |
Cold- or exercise-induced symptoms | 12/336 (3.6%) | 8/291 (2.7%) | 4/45 (8.9%) |
Episodes lasting ≥7 days | 12/336 (3.6%) | 10/291 3.4%) | 2/45 (4.4%) |
Diarrhea | 6/336 (1.8%) | 4/291 (1.4%) | 2/45 (4.4%) |
Chest pain | 4/336 (1.2%) | 2/291 (0.7%) | 2/45 (4.4%) |
Conjunctivitis | 3/336 (0.9%) | 3/291 (1.0%) | 0 |
Arthritis | 2/336 (0.6%) | 2/291 (0.7%) | 0 |
Periorbital edema | 2/336 (0.6%) | 2/291 (0.7%) | 0 |
Severe abdominal pain | 1/336 (0.3%) | 1/291 (0.3%) | 0 |
Sensorineural hearing loss | 1/336 (0.3%) | 1/291 (0.3%) | 0 |
More than one atypical symptom | 8/336 (2.4%) | 6/291 (2.1%) | 2/49 (4.4%) |