From: Colchicine versus cimetidine: the better choice for Periodic fever, aphthous stomatitis, pharyngitis, adenitis (PFAPA) syndrome prophylaxis, and the role of MEFV gene mutations
variable
Drug regimens
Mean ± SD
P valuea
P valueb
Three months before treatment
Three months after treatment
febrile attacks (number)
Colchicine
5.11 ± 2.03
2.17 ± 1.79
≤ 0.0001
0.88
Cimetidine
4.65 ± 2.15
2.52 ± 1.76