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Table 6 Factors associated with lung involvement in rheumatic diseases

From: Lung involvement in children with newly diagnosed rheumatic diseases: characteristics and associations

Variables

Univariate model 1

Multivariate model 1

Multivariate model 2

OR

95% CI

P-value

OR

95% CI

P-value

OR

95% CI

P-value

Age

0.951

0.751–1.205

0.679

0.812

0.598–1.104

0.183

0.831

0.581–1.188

0.309

Sex

(female)

3.492

1.012–12.051

0.048*

5.702

0.993–32.745

0.051

6.914

0.967–49.420

0.054

Type of disease

 SLE

11.667

1.940–70.178

0.007*

   

24.192

2.305–253.960

0.008*

 JIA

2.917

0.594–14.327

0.187

   

7.079

0.400–125.228

0.182

 JDM

6.667

0.597–74.506

0.123

   

6.106

0.338-110.314

0.220

 Others

Ref

     

Ref

  

 ESR

1.026

1.001–1.052

0.039*

1.037

1.003–1.072

0.032*

   

 CD4/CD8

5.625

1.145–27.638

0.033*

9.875

1.296–75.243

0.027*

6.778

0.770–59.641

0.085

  1. *P < 0.05 was considered statistically significant
  2. Abbreviations: OR Odds ratio, CI Confidence interval, SLE Systemic lupus erythematosus, JIA Juvenile idiopathic arthritis, JDM Juvenile dermatomyositis, CRP C-reactive protein, ESR Erythrocyte sedimentation rate, WBC White blood cell, HB Hemoglobin, PLT Platelet, ANA Antinuclear antibodies, RF Rheumatoid factor, IL Interleukin, TNF-a a-tumor necrosis factor, VitD3 Vitamin D3, NK Natural killer cells
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Pediatric Rheumatology

ISSN: 1546-0096