From: Proceedings of the 28th European Paediatric Rheumatology Congress (PReS 2022)
S. no. | Gene | Full forms | Function |
---|---|---|---|
1. | CXCL8 | C-X-C motif chemokine ligand 8 | Inflammatory cytokine |
2. | Pecam-1 | Platelet endothelial cell adhesion molecule | Migration of leukocytes, formation of vessels, and integrin activation |
3. | Pentraxin -3 | Â | Inflammatory mediator |
4. | ENDOGLIN | Â | Pro-angiogenic, protects endothelial cells and regulates NO-dependent vasodilatation |
5. | VEGF-A | Vascular endothelial growth factor | Induces proliferation and migration of vascular endothelial cells |
6 | Leptin | Â | Pro-inflammatory and promotes angiogenesis |
7 | Resistin | Â | Increases expression of endothelin-1, MCP-I, cytokines and upregulates adhesion molecules |
8 | Osteopontin | Â | Pro inflammatory cytokine, controls monocyte adhesion ,migration, survival, differentiation |