Table 4 Previous literature on changes of RANKL and OPG in SLE and other immune-related diseases
From: Bone remodeling serum markers in children with systemic lupus erythematosus
Authors | Publication year | Region | Disease | Patients /Controls NO | Age years | RANKL/OPG |
|---|---|---|---|---|---|---|
Ali et al. [10] | 2019 | Egypt | pSLE | 50/50 | 11.8 ± 2.99 | RANKL/OPG ratio was elevated in pSLE |
Sandal et al. [11] | 2017 | India | pSLE | 31/0 | 13.4 ± 3.2 | No different between active and inative disease |
Gupta et al. [12] | 2016 | India | LN | 127/24 | 12–50 | Urinary OPG/Cr was elevated in patients with LN |
Lien et al. [13] | 2010 | Norway | JIA | 90/90 | 10.1 ± 3.2 | RANKL/OPG ratio was elevated in JIA |
Wasilewska et al. [14] | 2010 | Poland | INS | 90/70 | 10.6 ± 5.5 | RANKL/OPG ratio was elevated in INS |
Ozkaya et al. [15] | 2007 | Turkey | CKD | 33/22 | 5–18 | OPG was elevated and RANKL was decreased in CKD |
Rouster-Stevens et al. [16] | 2007 | US | JDM | 37/44 | 6.3 ± 2.4 | RANKL/OPG ratio was elevated in JDM |