Uveitis associated with juvenile arthritis: a continued cohort study 40 years after uveitis onset

Table 3 Summary of results from all three follow-up of the same cohort

Mean follow-up time (years) from onset of uveitis	7.2	24.0	40.7
Mean age at follow-up (years)	13.2	31.0	46.9
Female sex (%)	34 (61.8)	29 (59.1)	16 (53.3)
Patients participating (% of original cohort)	55 (100)	49 (89.0)	30 (54.5)
EULAR ^a
O	46	41	26
P	6	5	2
S	3	3	2
ANA at diagnosis^b (% +)	40+ (72.2)	35+ (71.4)	23 + (76.6)
	13-	12-	6-
	2 u	2 u	1 u
Female sex with ANA+,	24	20	11
HLA-B27^c (%+)	13+ (23.6)	13+ (26.5)	8+ (26.6)
	29-	26-	18-
	13 u	10 u	4 u
Female sex with HLA-B27 +,	5	5	2
Patients with active uveitis^d (%)	28 (50.9)	27 (55.1)	13 (43.3)
Female sex with active uveitis	19	15	5
Number of patients with cataracts^e (%)	23 (41.8)	28 (57.1)	20 (66.6)
Female sex with cataracts	14	19	11
Number of patients with G/OH^f (%)	3 (5.4)	12 (24.4)	12 (40.0)
Female sex with G/OH	2	5	5
Number of patients with severe visual impairment in both eyes^g (%) of these, female sex	2 (3.6)	5 (10.2)	3 (10.0)
	2	3	1
Number of single eyes with severe visual impairment ^g (%) of these, female sex	12 (10.9)	17 (17.3)	14 (23.3)
	8	11	7
Number of patients with mild or no visual impairment in best eye (%) of these, female sex	49 (89.0)	29 (59.1)	20 (66.6)
	30	19	11
Number of single eyes with mild or no visual impairment (%) of these, female sex	84 (76.3)	49 (50.0)	36 (60.0)
	51	30	20

Severe visual impairment is defined as a vision score of poorer than 0.1 (Snellen 20/200)
Moderate visual impairment is defined as vision equal to or better than 0.1 and poorer than 0.3 (Snellen equal to or better than 20/200 and poorer than 20/70)
Mild or no visual impairment is defined as vision equal to or better than 0.3 (Snellen 20/70)
^a EULAR diagnostic classification at onset of Juvenile Chronic Arthritis: O=oligoarthritis, P=polyarthritis, S=systemic disease
^b Number of patients who were ANA positive (+), negative (-) or unknown (u) at diagnosis of joint disease
^c HLA-B27 positive (+), negative (-) or unknown (u)
^d The difference in the incidences of active uveitis at 7, 24, and 40 years was not significant
^e The increase in the number of patients with cataracts between 7 years and 24 years was significant (p=0.001), while the difference between 24 years and 40 years was not (p=1.000)
^f The increase in the number of patients with G/OH was statistically significant between the 7-year follow-up and the 24-year follow-up (p=0.004), while the difference between 24 and 40 years was not (p=0.250)
^g According to the World Health Organization classification of visual impairment

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