Feasibility of the wingate anaerobic exercise test as a clinical measure in patients with juvenile dermatomyositis

Table 2 Association of Wingate outcomes to clinical parameters

Variable	Absolute Peak Power (Watts)		Relative Peak Power (Watts/kg)		Fatigue Index
Variable	r	p-value	r	p-value	r	p-value
CHAQ	-0.38	0.074	-0.65	0.0009	-0.15	0.51
Patient Global Assessment	-0.38	0.071	-0.53	0.01	0.00	0.99
Physician Global Assessment	-0.58	0.004	-0.60	0.002	-0.10	0.65
Nail fold capillaroscopy	0.32^a	0.14	0.32^a	0.14	-0.17^a	0.44
MYOACT-VAS^b
Constitutional Disease Activity	-0.17	0.45	-0.44	0.036	-0.03	0.90
Cutaneous Disease Activity	-0.59	0.003	-0.54	0.008	-0.08	0.73
Skeletal Disease Activity	-0.49	0.017	-0.42	0.049	-0.06	0.77
Extra-muscular Global Assessment	-0.64	0.001	-0.57	0.004	-0.10	0.66
Muscle Disease Activity	-0.46	0.028	-0.63	0.001	0.00	0.99
Global Disease Activity	-0.62	0.002	-0.60	0.003	-0.05	0.81
ALT	-0.33	0.12	-0.41	0.051	-0.28	0.19
AST	-0.36	0.096	-0.44	0.034	-0.01	0.95
CK	-0.091	0.68	0.028	0.90	-0.26	0.24
LDH	-0.24	0.26	-0.33	0.12	-0.31	0.15
CMAS	0.59	0.003	0.78	< 0.0001	-0.07	0.76
MMT-8	0.71	< 0.0001	0.69	0.0002	0.22	0.32
Timed Squats	0.69	0.001	0.79	< 0.0001	-0.06	0.82

^aPearson’s product moment correlation coefficient
^bGastrointestinal disease activity, pulmonary disease activity, cardiovascular disease activity, and other disease activity are not reported as all scores were 0
Correlations between absolute peak power, relative peak power, and fatigue index, and clinical assessments. All r-values are Spearman’s rank correlation coefficients unless otherwise indicated. Abbreviations used: MYOACT-VAS Myositis Disease Activity Assessment Visual Analogue Scales, ALT Alanine Aminotransferase, AST Aspartate aminotransferase, CK creatine kinase, LDH lactate dehydrogenase, CMAS Childhood Myositis Assessment Scale, MMT-8 Manual Muscle Test

ISSN: 1546-0096